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ENSG00000188897
HPA
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  • ENSG00000188897
PROTEIN SUMMARY GENE INFORMATION RNA DATA ANTIBODY DATA
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

ENSG00000188897
Synonyms
Gene descriptioni

Full gene name according to HGNC.

Novel lipoprotein amino terminal region containing protein
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Intracellular
Protein evidence Evidence at transcript level (all genes)
GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Chromosome 16
Cytoband p13.13
Chromosome location (bp) 11359845 - 11527247
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

4
Ensembl ENSG00000188897 (version 109)
Entrez gene 400499
HGNC
UniProt
neXtProt
GeneCards ENSG00000188897
Antibodypedia ENSG00000188897 antibodies


PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
(predicted)
Transmembrane regions
(predicted)
ENST00000595168
ENSP00000472593
ENST00000595168
M0R2I5
[Direct mapping] Uncharacterized protein
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Show all
46 aa
4.9 kDa
No 0
ENST00000598234
ENSP00000470478
ENST00000598234
M0QZD8
[Direct mapping] Uncharacterized protein
Show all
   SCAMPI predicted membrane proteins
   THUMBUP predicted membrane proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
   DeepTMHMM predicted secreted proteins
   DeepSig predicted secreted proteins
Predicted intracellular proteins
Show all
GO:0005319 [lipid transporter activity]
GO:0006869 [lipid transport]
GO:0032355 [response to estradiol]
GO:0071391 [cellular response to estrogen stimulus]
Show all
3266 aa
357.8 kDa
Yes 0
ENST00000599216
ENSP00000472859
ENST00000599216
M0R2X1
[Direct mapping] VWFD domain-containing protein
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Show all
455 aa
49 kDa
No 0
ENST00000696174
ENSP00000512464
ENST00000696174
   SCAMPI predicted membrane proteins
   THUMBUP predicted membrane proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
   DeepTMHMM predicted secreted proteins
   DeepSig predicted secreted proteins
Predicted intracellular proteins
Show all
GO:0005319 [lipid transporter activity]
GO:0006869 [lipid transport]
Show all
3320 aa
363.3 kDa
Yes 0

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