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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:64.5 nTPM
HPA Brain:99.4 nTPM
GTEx:64.5 nTPM
FANTOM5:75.8 Scaled Tags Per Million
Pig:57.9 nTPM
Mouse:63.4 nTPM
Allen mouse:7.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

99.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 98.4
2586 Male, age 75, left hemisphere 149.0
2666 Male, age 74, left hemisphere 113.9
2828 Female, age 72, unknown 104.1
2019 Male, age 18, unknown 96.7
1827 Male, age 72, unknown 95.8
2219 Male, age 76, both hemispheres 94.0
1870 Female, age 42, unknown 86.5
1833 Male, age 53, unknown 83.9
1830 Male, age 51, unknown 83.2
2411 Female, age 72, unknown 76.8
Dorsal raphe nucleus
nTPM: 77.8
2750 Male, age 76, both hemispheres 87.5
2047 Male, age 72, unknown 81.8
1828 Male, age 53, unknown 80.6
2016 Female, age 72, unknown 71.7
2298 Female, age 72, unknown 67.6
Inferior colliculus
nTPM: 90.0
1890 Male, age 53, unknown 93.3
2849 Male, age 72, unknown 93.3
1848 Female, age 42, unknown 89.0
2097 Female, age 72, unknown 84.3
Median raphe nucleus
nTPM: 72.8
2220 Male, age 76, midline 72.8
Periaquaductal grey, anterior
nTPM: 97.1
1795 Male, age 51, unknown 102.1
2502 Female, age 75, unknown 97.7
1947 Male, age 18, unknown 91.5
Periaquaductal grey, dorsal
nTPM: 80.0
2464 Female, age 72, unknown 87.1
1831 Male, age 72, unknown 85.3
1840 Male, age 53, unknown 84.0
2850 Male, age 76, both hemispheres 63.4
Periaquaductal grey, lateral
nTPM: 81.9
2053 Male, age 18, unknown 87.0
2140 Male, age 76, both hemispheres 80.9
2272 Male, age 74, both hemispheres 77.9
Pretectal area
nTPM: 93.6
1944 Female, age 72, unknown 118.2
1816 Male, age 51, unknown 111.3
2007 Male, age 72, unknown 108.7
2407 Male, age 75, both hemispheres 99.7
1817 Female, age 42, unknown 96.9
1815 Male, age 53, unknown 96.6
2316 Male, age 76, right hemisphere 91.4
2825 Male, age 18, unknown 87.0
2667 Female, age 75, unknown 79.9
2224 Female, age 72, unknown 73.9
2273 Male, age 74, both hemispheres 65.9
Red nucleus
nTPM: 88.4
2584 Male, age 75, left hemisphere 111.3
2588 Male, age 74, left hemisphere 107.8
2785 Male, age 18, unknown 100.5
2769 Male, age 72, unknown 93.5
2227 Male, age 72, unknown 93.2
1865 Male, age 51, unknown 84.1
2503 Female, age 72, unknown 83.3
2725 Female, age 75, unknown 81.8
1904 Male, age 53, unknown 80.0
1954 Female, age 42, unknown 78.0
2823 Male, age 76, right hemisphere 76.5
1821 Female, age 72, unknown 70.8
Substantia nigra
nTPM: 84.2
2665 Male, age 74, both hemispheres 104.4
2583 Male, age 75, right hemisphere 102.4
2590 Female, age 75, unknown 92.1
1941 Male, age 53, unknown 91.6
1916 Female, age 42, unknown 88.3
1851 Male, age 51, unknown 84.5
1889 Female, age 72, unknown 84.3
2699 Male, age 18, unknown 70.4
2241 Male, age 72, unknown 63.8
2409 Female, age 72, unknown 59.9
Superior colliculus
nTPM: 99.4
2664 Male, age 75, both hemispheres 127.9
2668 Female, age 75, unknown 109.0
2087 Female, age 72, unknown 107.0
2261 Male, age 18, unknown 107.0
1796 Male, age 53, unknown 97.8
1913 Female, age 42, unknown 95.1
1839 Male, age 51, unknown 90.4
2587 Male, age 74, left hemisphere 89.3
1895 Male, age 76, right hemisphere 88.3
1995 Male, age 72, unknown 82.0
Ventral tegmental area
nTPM: 77.8
2223 Female, age 72, unknown 87.0
1915 Female, age 42, unknown 80.5
1942 Male, age 51, unknown 79.2
2021 Male, age 53, unknown 74.6
2218 Male, age 76, both hemispheres 72.9
2410 Female, age 72, unknown 72.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

64.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 64.5
Samples: 139

Max nTPM: 113.1
Min nTPM: 34.1
Std nTPM: 12.0
Median nTPM: 63.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 113.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 98.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 97.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 93.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 88.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 87.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 85.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 84.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 83.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 82.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 81.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 81.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 80.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 80.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 80.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 79.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 79.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 79.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 79.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 78.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 77.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 75.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 75.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 74.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 74.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 74.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 73.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 73.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 72.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 72.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 72.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 72.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 72.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 71.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 70.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 70.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 70.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 69.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 69.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 69.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 69.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 68.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 68.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 67.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 67.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 67.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 67.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 67.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 67.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 66.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 66.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 66.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 66.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 66.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 66.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 65.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 65.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 65.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 65.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 65.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 64.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 64.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 64.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 63.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 63.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 63.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 63.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 63.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 63.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 63.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 63.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 63.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 62.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 62.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 61.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 61.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 61.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 61.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 61.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 60.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 60.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 60.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 60.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 60.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 60.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 59.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 59.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 59.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 59.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 59.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 59.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 59.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 59.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 59.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 59.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 58.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 58.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 58.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 58.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 58.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 57.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 57.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 57.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 57.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 56.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 56.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 56.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 56.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 56.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 56.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 56.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 56.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 55.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 55.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 55.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 54.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 54.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 53.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 53.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 52.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 52.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 52.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 51.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 50.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 50.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 50.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 50.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 49.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 49.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 48.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 47.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 47.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 47.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 47.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 45.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 44.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 43.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 35.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 34.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

75.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 75.8
FF:10158-103A5 76 years, female 75.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

57.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 37.3
Samples: 4

Max nTPM: 45.7
Min nTPM: 31.1
Sample A Female 45.7
Sample B Female 31.1
Sample C Male 39.8
Sample D Male 32.5
Midbrain
nTPM: 49.6
Samples: 4

Max nTPM: 68.6
Min nTPM: 36.4
Sample A Female 36.4
Sample B Female 37.7
Sample C Male 68.6
Sample D Male 55.5
Periaqueductal gray
nTPM: 35.6
Samples: 3

Max nTPM: 41.0
Min nTPM: 30.9
Sample B Female 35.0
Sample C Male 41.0
Sample D Male 30.9
Superior colliculi
nTPM: 57.9
Samples: 4

Max nTPM: 70.3
Min nTPM: 41.7
Sample A Female 63.9
Sample B Female 41.7
Sample C Male 70.3
Sample D Male 55.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

63.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 63.4
Samples: 4

Max nTPM: 65.3
Min nTPM: 60.6
Sample A Male 64.5
Sample B Male 60.6
Sample C Female 63.1
Sample D Female 65.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

7.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.1
71211353 Antisense, RP_050816_01_C11, Mouse strain C57BL/6J (56 days, male) 7.1

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