We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
165.4
nTPM
HPA:
165.4
nTPM
GTEx:
75.7
nTPM
FANTOM5:
424.9
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA007162
Antibody CAB035986
Antibody CAB062546
Cholangiocytes
Not detected
Not detected
Not detected
Hepatocytes
Medium
High
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
165.4
Female, age 60
Liver sample 21 nTPM: 116.8
Male, age 54
Liver sample 23 nTPM: 111.9
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 129.6
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 299.6
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 145
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 114.8
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 172
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 149
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 99.4
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 316.5
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
75.7
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 75.7
Samples: 226
Max nTPM: 205.2
Min nTPM: 17.5
Std nTPM: 35.1
Median nTPM: 68.1
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
205.2
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
187.2
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
175.1
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
161.0
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
160.5
GTEX-17HHE-0126-SM-79398
50-59 years, male
160.2
GTEX-18A66-2026-SM-7189C
60-69 years, male
158.7
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
158.5
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
157.2
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
155.3
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
152.3
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
152.0
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
144.7
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
142.8
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
140.8
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
138.5
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
135.9
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
134.9
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
130.6
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
127.7
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
126.4
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
125.5
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
122.6
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
122.1
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
121.8
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
120.4
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
120.3
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
115.4
GTEX-14PJO-1726-SM-68719
60-69 years, male
114.5
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
113.7
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
113.7
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
113.3
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
113.3
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
113.0
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
111.8
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
110.6
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
109.6
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
107.2
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
106.4
GTEX-S32W-1926-SM-4AD63
50-59 years, female
106.1
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
106.1
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
105.7
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
105.3
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
104.2
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
103.6
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
102.7
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
102.4
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
100.8
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
100.8
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
99.9
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
99.8
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
99.3
GTEX-YECK-1926-SM-4W21H
60-69 years, male
98.6
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
98.3
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
97.5
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
97.1
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
97.0
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
96.9
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
95.7
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
94.5
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
94.3
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
94.2
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
93.6
GTEX-18465-1626-SM-7LG6N
50-59 years, male
92.4
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
92.4
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
92.0
GTEX-14JG1-1626-SM-664NH
40-49 years, male
91.2
GTEX-RU72-1426-SM-46MUF
50-59 years, female
90.6
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
89.6
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
87.9
GTEX-R53T-0326-SM-48FEC
50-59 years, female
87.1
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
86.0
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
85.5
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
85.5
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
85.3
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
85.3
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
85.2
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
85.1
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
84.4
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
83.7
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
83.6
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
82.4
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
82.1
GTEX-RN64-1826-SM-48FDV
50-59 years, male
81.4
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
80.9
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
80.6
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
80.5
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
79.7
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
78.0
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
78.0
GTEX-1B933-1226-SM-731DW
50-59 years, female
77.9
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
77.7
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
76.4
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
76.1
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
75.9
GTEX-13113-1326-SM-5GCOI
60-69 years, female
75.3
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
75.1
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
74.7
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
74.6
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
74.5
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
74.0
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
72.8
GTEX-18A7A-1526-SM-72D69
50-59 years, female
71.6
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
71.5
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
71.3
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
71.2
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
71.0
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
70.7
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
69.5
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
69.1
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
68.8
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
68.6
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
68.3
GTEX-P78B-1326-SM-3P611
40-49 years, female
67.8
GTEX-11ZUS-2526-SM-59872
30-39 years, male
67.7
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
67.0
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
66.5
GTEX-14E7W-1526-SM-6871X
70-79 years, male
66.3
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
65.8
GTEX-14PHX-0526-SM-664NW
50-59 years, male
65.4
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
65.1
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
64.7
GTEX-QESD-2026-SM-447BI
20-29 years, male
63.5
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
62.1
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
62.1
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
62.1
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
61.8
GTEX-14XAO-0226-SM-68728
60-69 years, female
61.6
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
61.2
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
61.0
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
60.9
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
60.7
GTEX-QEL4-1226-SM-447A4
50-59 years, male
60.3
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
60.2
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
59.9
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
59.8
GTEX-12696-0826-SM-5EGGE
60-69 years, male
59.3
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
59.3
GTEX-144GL-1426-SM-79OMA
50-59 years, male
59.2
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
59.1
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
58.8
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
58.7
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
58.2
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
58.2
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
57.8
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
57.5
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
56.5
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
56.3
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
56.2
GTEX-13112-1426-SM-5EGH8
50-59 years, male
55.8
GTEX-1399T-0826-SM-5IFES
60-69 years, male
55.6
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
55.5
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
55.5
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
55.4
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
54.7
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
54.7
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
54.0
GTEX-REY6-1226-SM-48FDR
60-69 years, male
53.8
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
53.8
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
53.3
GTEX-1B932-1426-SM-793AN
40-49 years, female
53.1
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
52.6
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
52.5
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
52.4
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
51.1
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
51.0
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
50.6
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
50.5
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
50.3
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
49.9
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
49.9
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
49.8
GTEX-S33H-1626-SM-4AD68
30-39 years, male
49.6
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
49.4
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
49.2
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
49.1
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
48.8
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
48.7
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
47.0
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
46.8
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
46.3
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
45.8
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
45.2
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
45.0
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
44.6
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
44.4
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
44.3
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
44.2
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
43.6
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
43.0
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
42.3
GTEX-X261-1726-SM-4PQYT
50-59 years, male
41.4
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
41.3
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
40.9
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
40.5
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
40.2
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
38.8
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
38.6
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
38.3
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
37.6
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
37.4
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
36.7
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
36.3
GTEX-Q734-0326-SM-48U15
40-49 years, female
36.3
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
35.6
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
35.5
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
34.5
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
34.5
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
34.4
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
33.6
GTEX-O5YV-0726-SM-EV798
60-69 years, female
33.5
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
32.7
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
32.2
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
32.1
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
32.0
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
31.6
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
31.6
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
31.3
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
30.9
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
29.4
GTEX-11GSP-0626-SM-5986T
60-69 years, female
27.0
GTEX-17F96-1226-SM-79OK2
70-79 years, male
27.0
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
26.8
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
20.4
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
19.8
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
17.5
Show allShow less
LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
