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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:16.1 nTPM
HPA Brain:41.3 nTPM
GTEx:16.1 nTPM
FANTOM5:51.2 Scaled Tags Per Million
Pig:73.8 nTPM
Mouse:109.0 nTPM
Allen mouse:3.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

41.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 29.4
2219 Male, age 76, both hemispheres 37.0
2019 Male, age 18, unknown 36.9
2411 Female, age 72, unknown 32.9
1827 Male, age 72, unknown 30.4
2666 Male, age 74, left hemisphere 30.4
1833 Male, age 53, unknown 28.6
1870 Female, age 42, unknown 26.7
1830 Male, age 51, unknown 25.6
2586 Male, age 75, left hemisphere 24.7
2828 Female, age 72, unknown 21.1
Dorsal raphe nucleus
nTPM: 31.6
2298 Female, age 72, unknown 34.9
1828 Male, age 53, unknown 34.6
2750 Male, age 76, both hemispheres 32.3
2047 Male, age 72, unknown 31.3
2016 Female, age 72, unknown 24.9
Inferior colliculus
nTPM: 27.1
2097 Female, age 72, unknown 32.9
1890 Male, age 53, unknown 27.3
1848 Female, age 42, unknown 26.4
2849 Male, age 72, unknown 21.8
Median raphe nucleus
nTPM: 37.0
2220 Male, age 76, midline 37.0
Periaquaductal grey, anterior
nTPM: 31.3
1947 Male, age 18, unknown 34.8
2502 Female, age 75, unknown 33.0
1795 Male, age 51, unknown 26.1
Periaquaductal grey, dorsal
nTPM: 24.6
2464 Female, age 72, unknown 26.2
1831 Male, age 72, unknown 25.3
1840 Male, age 53, unknown 24.8
2850 Male, age 76, both hemispheres 22.1
Periaquaductal grey, lateral
nTPM: 21.5
2272 Male, age 74, both hemispheres 25.5
2053 Male, age 18, unknown 20.1
2140 Male, age 76, both hemispheres 18.9
Pretectal area
nTPM: 31.0
1944 Female, age 72, unknown 42.7
1816 Male, age 51, unknown 39.9
2007 Male, age 72, unknown 39.8
1817 Female, age 42, unknown 38.5
1815 Male, age 53, unknown 33.5
2273 Male, age 74, both hemispheres 29.0
2224 Female, age 72, unknown 28.7
2667 Female, age 75, unknown 26.7
2407 Male, age 75, both hemispheres 23.1
2825 Male, age 18, unknown 20.7
2316 Male, age 76, right hemisphere 18.6
Red nucleus
nTPM: 27.1
1821 Female, age 72, unknown 37.3
2725 Female, age 75, unknown 29.8
2785 Male, age 18, unknown 29.4
1954 Female, age 42, unknown 29.1
1865 Male, age 51, unknown 26.0
2584 Male, age 75, left hemisphere 26.0
2227 Male, age 72, unknown 25.7
2503 Female, age 72, unknown 25.3
1904 Male, age 53, unknown 25.1
2588 Male, age 74, left hemisphere 24.1
2769 Male, age 72, unknown 23.9
2823 Male, age 76, right hemisphere 23.8
Substantia nigra
nTPM: 41.3
1916 Female, age 42, unknown 64.8
2241 Male, age 72, unknown 54.0
1941 Male, age 53, unknown 49.6
1851 Male, age 51, unknown 46.8
1889 Female, age 72, unknown 41.7
2409 Female, age 72, unknown 37.7
2699 Male, age 18, unknown 36.1
2665 Male, age 74, both hemispheres 30.0
2590 Female, age 75, unknown 26.6
2583 Male, age 75, right hemisphere 25.3
Superior colliculus
nTPM: 27.2
2668 Female, age 75, unknown 37.9
2087 Female, age 72, unknown 33.8
2261 Male, age 18, unknown 28.8
1895 Male, age 76, right hemisphere 28.6
2587 Male, age 74, left hemisphere 26.4
1839 Male, age 51, unknown 26.2
1796 Male, age 53, unknown 24.8
2664 Male, age 75, both hemispheres 23.2
1913 Female, age 42, unknown 22.2
1995 Male, age 72, unknown 19.6
Ventral tegmental area
nTPM: 33.4
2218 Male, age 76, both hemispheres 41.0
1915 Female, age 42, unknown 40.4
2410 Female, age 72, unknown 39.6
1942 Male, age 51, unknown 29.4
2223 Female, age 72, unknown 26.1
2021 Male, age 53, unknown 24.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

16.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 16.1
Samples: 139

Max nTPM: 44.0
Min nTPM: 7.0
Std nTPM: 6.7
Median nTPM: 14.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 44.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 37.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 34.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 31.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 30.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 29.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 28.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 28.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 27.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 27.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 27.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 26.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 26.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 26.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 25.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 23.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 23.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 23.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 23.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 23.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 22.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 22.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 22.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 22.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 22.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 21.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 21.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 21.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 21.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 21.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 20.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 20.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 20.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 20.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 20.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 20.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 19.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 19.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 19.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 19.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 19.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 19.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 19.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 19.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 18.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 18.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 18.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 18.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 18.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 17.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 17.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 17.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 16.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 16.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 16.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 16.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 16.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 15.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 15.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 15.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 15.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 15.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 15.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 15.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 15.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 14.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 14.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 14.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 14.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 14.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 14.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 14.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 14.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 14.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 14.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 13.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 13.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 13.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 13.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 13.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 13.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 13.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 12.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 12.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 12.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 12.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 12.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 12.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 11.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 11.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 11.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 11.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 11.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 11.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 11.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 11.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 11.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 11.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 11.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 11.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 11.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 10.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 10.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 10.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 10.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 10.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 10.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 10.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 10.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 10.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 10.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 10.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 10.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 10.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 10.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 10.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 10.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 10.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 9.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 9.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 9.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 9.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 9.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 9.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 9.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 9.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 9.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 8.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 8.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 8.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 8.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 8.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 8.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 8.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 8.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 8.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 8.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 7.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 7.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

51.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 51.2
FF:10158-103A5 76 years, female 51.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

73.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 68.9
Samples: 4

Max nTPM: 88.3
Min nTPM: 48.1
Sample A Female 88.3
Sample B Female 55.5
Sample C Male 83.6
Sample D Male 48.1
Midbrain
nTPM: 67.5
Samples: 4

Max nTPM: 78.6
Min nTPM: 46.9
Sample A Female 46.9
Sample B Female 68.2
Sample C Male 76.4
Sample D Male 78.6
Periaqueductal gray
nTPM: 62.7
Samples: 3

Max nTPM: 71.9
Min nTPM: 56.3
Sample B Female 59.8
Sample C Male 71.9
Sample D Male 56.3
Superior colliculi
nTPM: 73.8
Samples: 4

Max nTPM: 90.2
Min nTPM: 45.0
Sample A Female 90.2
Sample B Female 45.0
Sample C Male 85.7
Sample D Male 74.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

109.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 109.1
Samples: 4

Max nTPM: 112.1
Min nTPM: 107.0
Sample A Male 107.0
Sample B Male 112.1
Sample C Female 110.1
Sample D Female 107.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.9
532629 Antisense, RP_040810_02_G04, Mouse strain C57BL/6J (56 days, male) 3.9

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