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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:20.6 nTPM
HPA Brain:12.3 nTPM
GTEx:20.6 nTPM
FANTOM5:77.2 Scaled Tags Per Million
Mouse:0.0 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

12.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 7.3
1870 Female, age 42, unknown 10.2
2666 Male, age 74, left hemisphere 9.9
1830 Male, age 51, unknown 9.7
2019 Male, age 18, unknown 8.2
2828 Female, age 72, unknown 7.7
1833 Male, age 53, unknown 6.7
2586 Male, age 75, left hemisphere 5.9
1827 Male, age 72, unknown 5.6
2411 Female, age 72, unknown 5.2
2219 Male, age 76, both hemispheres 3.7
Dorsal raphe nucleus
nTPM: 11.4
2298 Female, age 72, unknown 14.3
2016 Female, age 72, unknown 14.2
1828 Male, age 53, unknown 11.6
2750 Male, age 76, both hemispheres 9.8
2047 Male, age 72, unknown 7.0
Inferior colliculus
nTPM: 7.3
2097 Female, age 72, unknown 8.2
1890 Male, age 53, unknown 7.8
2849 Male, age 72, unknown 6.6
1848 Female, age 42, unknown 6.5
Median raphe nucleus
nTPM: 12.3
2220 Male, age 76, midline 12.3
Periaquaductal grey, anterior
nTPM: 6.8
1795 Male, age 51, unknown 9.1
1947 Male, age 18, unknown 6.4
2502 Female, age 75, unknown 4.9
Periaquaductal grey, dorsal
nTPM: 10.2
1831 Male, age 72, unknown 14.4
2850 Male, age 76, both hemispheres 13.3
1840 Male, age 53, unknown 6.6
2464 Female, age 72, unknown 6.5
Periaquaductal grey, lateral
nTPM: 11.9
2272 Male, age 74, both hemispheres 12.9
2140 Male, age 76, both hemispheres 12.2
2053 Male, age 18, unknown 10.6
Pretectal area
nTPM: 8.9
2407 Male, age 75, both hemispheres 14.2
2316 Male, age 76, right hemisphere 13.0
2273 Male, age 74, both hemispheres 11.6
2224 Female, age 72, unknown 10.8
1944 Female, age 72, unknown 8.4
1817 Female, age 42, unknown 8.2
2007 Male, age 72, unknown 8.1
2825 Male, age 18, unknown 7.6
1815 Male, age 53, unknown 7.3
2667 Female, age 75, unknown 4.9
1816 Male, age 51, unknown 3.8
Red nucleus
nTPM: 8.4
2725 Female, age 75, unknown 12.7
1865 Male, age 51, unknown 11.9
2503 Female, age 72, unknown 9.8
2785 Male, age 18, unknown 8.3
2769 Male, age 72, unknown 8.1
2227 Male, age 72, unknown 8.0
2823 Male, age 76, right hemisphere 7.8
2584 Male, age 75, left hemisphere 7.4
1904 Male, age 53, unknown 7.1
1821 Female, age 72, unknown 6.9
1954 Female, age 42, unknown 6.3
2588 Male, age 74, left hemisphere 6.1
Substantia nigra
nTPM: 10.2
2699 Male, age 18, unknown 14.3
1941 Male, age 53, unknown 13.8
2590 Female, age 75, unknown 13.5
2665 Male, age 74, both hemispheres 12.4
2409 Female, age 72, unknown 10.7
2241 Male, age 72, unknown 9.2
1851 Male, age 51, unknown 8.8
2583 Male, age 75, right hemisphere 7.8
1916 Female, age 42, unknown 7.1
1889 Female, age 72, unknown 4.8
Superior colliculus
nTPM: 9.0
1913 Female, age 42, unknown 15.4
1995 Male, age 72, unknown 13.7
2587 Male, age 74, left hemisphere 12.1
2668 Female, age 75, unknown 8.6
2087 Female, age 72, unknown 8.3
1839 Male, age 51, unknown 7.7
1796 Male, age 53, unknown 6.9
2664 Male, age 75, both hemispheres 6.7
2261 Male, age 18, unknown 6.2
1895 Male, age 76, right hemisphere 4.6
Ventral tegmental area
nTPM: 11.7
2021 Male, age 53, unknown 16.7
2218 Male, age 76, both hemispheres 14.4
1915 Female, age 42, unknown 11.2
1942 Male, age 51, unknown 10.6
2223 Female, age 72, unknown 9.1
2410 Female, age 72, unknown 8.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

20.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 20.6
Samples: 139

Max nTPM: 146.5
Min nTPM: 1.1
Std nTPM: 25.6
Median nTPM: 10.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 146.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 116.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 116.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 111.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 100.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 86.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 85.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 67.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 67.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 66.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 60.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 60.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 57.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 53.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 49.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 46.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 44.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 41.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 40.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 40.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 37.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 34.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 34.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 33.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 33.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 32.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 30.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 27.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 27.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 27.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 26.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 26.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 26.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 25.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 24.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 23.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 23.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 21.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 21.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 20.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 20.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 19.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 19.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 18.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 18.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 18.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 18.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 17.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 17.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 17.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 16.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 16.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 16.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 15.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 15.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 15.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 15.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 15.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 14.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 14.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 13.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 13.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 13.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 13.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 13.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 12.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 12.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 12.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 11.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 10.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 9.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 9.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 9.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 9.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 9.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 9.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 9.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 8.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 8.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 8.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 8.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 8.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 8.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 8.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 7.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 7.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 7.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 7.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 7.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 7.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 7.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 7.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 7.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 6.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 6.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 6.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 6.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 6.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 5.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 5.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 5.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 5.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 5.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 5.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 5.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 4.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 4.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 4.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 4.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 4.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 4.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 4.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 4.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 4.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 4.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 3.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 3.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 3.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 3.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 3.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 3.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 3.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 3.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 3.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 3.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 3.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 3.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 2.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 2.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 2.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 2.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 2.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 2.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 2.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

77.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 77.2
FF:10158-103A5 76 years, female 77.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 0.1
Samples: 4

Max nTPM: 0.1
Min nTPM: 0.0
Sample A Male 0.1
Sample B Male 0.0
Sample C Female 0.0
Sample D Female 0.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
68410399 Antisense, RP_041214_01_G10, Mouse strain C57BL/6J (56 days, male) 0.2
75084134 Antisense, RP_060412_04_D09, Mouse strain C57BL/6J (56 days, male) 0.2
71570746 Antisense, RP_050512_01_E07, Mouse strain C57BL/6J (56 days, male) 0.1
68301228 Antisense, RP_041129_02_H03, Mouse strain C57BL/6J (56 days, male) 0.0
Midbrain
Expression energy: 0.1
68410399 Antisense, RP_041214_01_G10, Mouse strain C57BL/6J (56 days, male) 0.2
75084134 Antisense, RP_060412_04_D09, Mouse strain C57BL/6J (56 days, male) 0.2
71570746 Antisense, RP_050512_01_E07, Mouse strain C57BL/6J (56 days, male) 0.1
68301228 Antisense, RP_041129_02_H03, Mouse strain C57BL/6J (56 days, male) 0.0
Midbrain
Expression energy: 0.1
68410399 Antisense, RP_041214_01_G10, Mouse strain C57BL/6J (56 days, male) 0.2
75084134 Antisense, RP_060412_04_D09, Mouse strain C57BL/6J (56 days, male) 0.2
71570746 Antisense, RP_050512_01_E07, Mouse strain C57BL/6J (56 days, male) 0.1
68301228 Antisense, RP_041129_02_H03, Mouse strain C57BL/6J (56 days, male) 0.0
Midbrain
Expression energy: 0.1
68410399 Antisense, RP_041214_01_G10, Mouse strain C57BL/6J (56 days, male) 0.2
75084134 Antisense, RP_060412_04_D09, Mouse strain C57BL/6J (56 days, male) 0.2
71570746 Antisense, RP_050512_01_E07, Mouse strain C57BL/6J (56 days, male) 0.1
68301228 Antisense, RP_041129_02_H03, Mouse strain C57BL/6J (56 days, male) 0.0
Midbrain
Expression energy: 0.1
68410399 Antisense, RP_041214_01_G10, Mouse strain C57BL/6J (56 days, male) 0.2
75084134 Antisense, RP_060412_04_D09, Mouse strain C57BL/6J (56 days, male) 0.2
71570746 Antisense, RP_050512_01_E07, Mouse strain C57BL/6J (56 days, male) 0.1
68301228 Antisense, RP_041129_02_H03, Mouse strain C57BL/6J (56 days, male) 0.0

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