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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:92.5 nTPM
HPA Brain:119.4 nTPM
GTEx:92.5 nTPM
FANTOM5:111.4 Scaled Tags Per Million
Pig:24.9 nTPM
Mouse:71.5 nTPM
Allen mouse:1.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

119.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 27.4
1870 Female, age 42, unknown 50.2
2666 Male, age 74, left hemisphere 39.4
2411 Female, age 72, unknown 33.5
1830 Male, age 51, unknown 31.7
2828 Female, age 72, unknown 30.4
1827 Male, age 72, unknown 22.9
1833 Male, age 53, unknown 20.5
2019 Male, age 18, unknown 16.1
2586 Male, age 75, left hemisphere 16.1
2219 Male, age 76, both hemispheres 13.5
Dorsal raphe nucleus
nTPM: 105.1
2047 Male, age 72, unknown 157.9
1828 Male, age 53, unknown 147.2
2298 Female, age 72, unknown 93.0
2016 Female, age 72, unknown 89.3
2750 Male, age 76, both hemispheres 38.3
Inferior colliculus
nTPM: 24.3
2097 Female, age 72, unknown 34.3
1890 Male, age 53, unknown 24.2
1848 Female, age 42, unknown 20.6
2849 Male, age 72, unknown 18.3
Median raphe nucleus
nTPM: 76.9
2220 Male, age 76, midline 76.9
Periaquaductal grey, anterior
nTPM: 119.4
1947 Male, age 18, unknown 180.1
1795 Male, age 51, unknown 109.9
2502 Female, age 75, unknown 68.3
Periaquaductal grey, dorsal
nTPM: 58.7
2850 Male, age 76, both hemispheres 127.7
1831 Male, age 72, unknown 48.9
2464 Female, age 72, unknown 31.9
1840 Male, age 53, unknown 26.3
Periaquaductal grey, lateral
nTPM: 76.0
2272 Male, age 74, both hemispheres 92.9
2140 Male, age 76, both hemispheres 79.3
2053 Male, age 18, unknown 55.8
Pretectal area
nTPM: 43.3
2273 Male, age 74, both hemispheres 101.3
2825 Male, age 18, unknown 81.0
2224 Female, age 72, unknown 71.2
2667 Female, age 75, unknown 50.0
2407 Male, age 75, both hemispheres 49.8
2316 Male, age 76, right hemisphere 39.6
1817 Female, age 42, unknown 22.0
1944 Female, age 72, unknown 19.2
1816 Male, age 51, unknown 16.1
1815 Male, age 53, unknown 15.6
2007 Male, age 72, unknown 11.0
Red nucleus
nTPM: 60.5
1954 Female, age 42, unknown 121.3
1865 Male, age 51, unknown 101.0
1821 Female, age 72, unknown 100.5
2227 Male, age 72, unknown 69.5
2769 Male, age 72, unknown 67.1
1904 Male, age 53, unknown 66.2
2725 Female, age 75, unknown 50.5
2823 Male, age 76, right hemisphere 47.8
2503 Female, age 72, unknown 39.4
2588 Male, age 74, left hemisphere 23.0
2584 Male, age 75, left hemisphere 21.8
2785 Male, age 18, unknown 17.3
Substantia nigra
nTPM: 36.8
1941 Male, age 53, unknown 101.8
2590 Female, age 75, unknown 39.0
1851 Male, age 51, unknown 36.2
2699 Male, age 18, unknown 35.7
2665 Male, age 74, both hemispheres 35.1
2409 Female, age 72, unknown 27.3
1916 Female, age 42, unknown 25.6
2241 Male, age 72, unknown 24.3
1889 Female, age 72, unknown 22.6
2583 Male, age 75, right hemisphere 20.6
Superior colliculus
nTPM: 40.4
1995 Male, age 72, unknown 67.4
2587 Male, age 74, left hemisphere 63.0
1913 Female, age 42, unknown 59.2
2261 Male, age 18, unknown 51.5
2664 Male, age 75, both hemispheres 40.6
2668 Female, age 75, unknown 34.3
1796 Male, age 53, unknown 25.9
2087 Female, age 72, unknown 25.2
1839 Male, age 51, unknown 24.8
1895 Male, age 76, right hemisphere 12.0
Ventral tegmental area
nTPM: 57.8
2223 Female, age 72, unknown 76.5
1915 Female, age 42, unknown 66.7
1942 Male, age 51, unknown 62.7
2021 Male, age 53, unknown 58.3
2410 Female, age 72, unknown 42.1
2218 Male, age 76, both hemispheres 40.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

92.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 92.5
Samples: 139

Max nTPM: 288.0
Min nTPM: 24.4
Std nTPM: 49.1
Median nTPM: 82.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 288.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 242.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 241.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 236.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 216.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 200.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 200.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 200.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 187.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 185.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 179.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 171.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 166.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 165.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 158.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 157.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 146.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 146.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 145.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 138.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 136.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 134.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 132.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 130.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 127.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 124.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 122.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 122.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 119.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 118.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 115.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 115.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 113.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 112.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 111.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 111.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 111.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 108.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 107.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 105.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 105.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 104.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 103.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 102.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 102.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 101.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 101.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 100.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 100.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 98.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 97.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 97.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 96.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 96.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 93.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 93.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 92.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 90.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 90.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 89.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 87.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 87.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 87.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 86.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 85.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 85.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 84.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 84.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 84.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 82.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 79.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 79.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 79.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 78.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 78.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 76.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 76.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 76.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 75.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 74.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 73.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 73.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 73.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 71.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 71.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 71.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 71.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 69.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 67.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 63.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 62.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 62.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 61.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 61.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 61.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 61.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 60.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 60.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 59.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 58.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 58.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 57.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 57.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 56.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 55.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 54.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 53.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 52.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 52.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 51.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 50.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 50.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 49.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 49.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 49.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 49.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 48.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 48.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 47.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 46.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 46.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 46.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 44.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 43.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 43.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 43.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 42.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 42.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 41.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 41.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 40.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 38.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 38.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 37.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 35.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 35.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 34.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 34.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 24.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

111.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 111.4
FF:10158-103A5 76 years, female 111.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

24.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 23.4
Samples: 4

Max nTPM: 28.5
Min nTPM: 18.5
Sample A Female 27.2
Sample B Female 28.5
Sample C Male 19.2
Sample D Male 18.5
Midbrain
nTPM: 18.7
Samples: 4

Max nTPM: 32.2
Min nTPM: 12.9
Sample A Female 32.2
Sample B Female 16.6
Sample C Male 13.1
Sample D Male 12.9
Periaqueductal gray
nTPM: 19.2
Samples: 3

Max nTPM: 24.8
Min nTPM: 14.7
Sample B Female 14.7
Sample C Male 24.8
Sample D Male 18.2
Superior colliculi
nTPM: 24.9
Samples: 4

Max nTPM: 44.8
Min nTPM: 15.0
Sample A Female 22.6
Sample B Female 44.8
Sample C Male 17.2
Sample D Male 15.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

71.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 71.5
Samples: 4

Max nTPM: 78.7
Min nTPM: 68.4
Sample A Male 68.5
Sample B Male 68.4
Sample C Female 70.3
Sample D Female 78.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.1
70560277 Antisense, RP_050330_01_A11, Mouse strain C57BL/6J (56 days, male) 1.8
79760442 Antisense, RP_071204_02_E10, Mouse strain C57BL/6J (56 days, male) 0.5

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