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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:21.1 nTPM
HPA Brain:143.3 nTPM
GTEx:21.1 nTPM
FANTOM5:196.4 Scaled Tags Per Million
Pig:135.6 nTPM
Mouse:86.3 nTPM
Allen mouse:6.8 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

143.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 120.1
2219 Male, age 76, both hemispheres 152.9
2411 Female, age 72, unknown 146.1
1833 Male, age 53, unknown 121.1
2019 Male, age 18, unknown 121.0
1870 Female, age 42, unknown 120.3
1827 Male, age 72, unknown 119.5
1830 Male, age 51, unknown 117.0
2666 Male, age 74, left hemisphere 111.4
2828 Female, age 72, unknown 98.0
2586 Male, age 75, left hemisphere 93.6
Dorsal raphe nucleus
nTPM: 113.3
2750 Male, age 76, both hemispheres 155.1
1828 Male, age 53, unknown 109.5
2047 Male, age 72, unknown 108.1
2298 Female, age 72, unknown 103.8
2016 Female, age 72, unknown 89.9
Inferior colliculus
nTPM: 114.3
2097 Female, age 72, unknown 122.3
1890 Male, age 53, unknown 116.8
1848 Female, age 42, unknown 109.5
2849 Male, age 72, unknown 108.5
Median raphe nucleus
nTPM: 143.3
2220 Male, age 76, midline 143.3
Periaquaductal grey, anterior
nTPM: 111.8
1947 Male, age 18, unknown 121.6
2502 Female, age 75, unknown 116.2
1795 Male, age 51, unknown 97.6
Periaquaductal grey, dorsal
nTPM: 95.7
1831 Male, age 72, unknown 108.0
2464 Female, age 72, unknown 104.0
1840 Male, age 53, unknown 94.1
2850 Male, age 76, both hemispheres 76.9
Periaquaductal grey, lateral
nTPM: 83.7
2053 Male, age 18, unknown 96.0
2272 Male, age 74, both hemispheres 83.2
2140 Male, age 76, both hemispheres 71.8
Pretectal area
nTPM: 120.4
1816 Male, age 51, unknown 162.8
2007 Male, age 72, unknown 148.7
1944 Female, age 72, unknown 147.8
1815 Male, age 53, unknown 143.4
1817 Female, age 42, unknown 141.5
2407 Male, age 75, both hemispheres 112.3
2825 Male, age 18, unknown 107.3
2316 Male, age 76, right hemisphere 99.8
2224 Female, age 72, unknown 96.4
2667 Female, age 75, unknown 92.7
2273 Male, age 74, both hemispheres 71.9
Red nucleus
nTPM: 130.4
1821 Female, age 72, unknown 149.7
2588 Male, age 74, left hemisphere 149.7
2503 Female, age 72, unknown 147.7
2823 Male, age 76, right hemisphere 146.4
2725 Female, age 75, unknown 134.1
1865 Male, age 51, unknown 128.3
2584 Male, age 75, left hemisphere 126.2
1904 Male, age 53, unknown 124.5
1954 Female, age 42, unknown 121.2
2785 Male, age 18, unknown 117.3
2227 Male, age 72, unknown 109.9
2769 Male, age 72, unknown 109.2
Substantia nigra
nTPM: 132.2
2241 Male, age 72, unknown 159.7
1941 Male, age 53, unknown 154.9
1889 Female, age 72, unknown 151.5
2409 Female, age 72, unknown 147.1
1916 Female, age 42, unknown 144.3
1851 Male, age 51, unknown 133.3
2590 Female, age 75, unknown 118.8
2583 Male, age 75, right hemisphere 115.2
2699 Male, age 18, unknown 108.5
2665 Male, age 74, both hemispheres 88.3
Superior colliculus
nTPM: 119.3
2668 Female, age 75, unknown 149.6
1895 Male, age 76, right hemisphere 144.8
2087 Female, age 72, unknown 142.3
2261 Male, age 18, unknown 131.7
1913 Female, age 42, unknown 120.0
2587 Male, age 74, left hemisphere 115.5
1796 Male, age 53, unknown 108.2
1839 Male, age 51, unknown 107.1
1995 Male, age 72, unknown 99.4
2664 Male, age 75, both hemispheres 74.2
Ventral tegmental area
nTPM: 122.5
2410 Female, age 72, unknown 150.8
2218 Male, age 76, both hemispheres 150.7
1915 Female, age 42, unknown 121.0
2223 Female, age 72, unknown 112.9
1942 Male, age 51, unknown 108.2
2021 Male, age 53, unknown 91.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

21.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 21.1
Samples: 139

Max nTPM: 65.2
Min nTPM: 4.6
Std nTPM: 10.1
Median nTPM: 19.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 65.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 52.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 51.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 47.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 44.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 41.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 36.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 36.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 36.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 36.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 35.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 34.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 33.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 32.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 32.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 32.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 31.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 31.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 31.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 31.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 30.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 30.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 30.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 30.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 30.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 29.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 29.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 29.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 29.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 29.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 29.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 28.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 28.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 28.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 27.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 27.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 27.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 26.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 26.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 26.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 26.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 25.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 25.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 24.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 24.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 23.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 23.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 23.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 23.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 22.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 22.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 22.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 22.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 22.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 22.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 22.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 21.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 21.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 21.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 21.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 21.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 20.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 20.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 20.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 20.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 20.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 20.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 20.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 19.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 19.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 19.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 19.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 19.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 18.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 18.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 18.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 18.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 18.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 18.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 17.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 17.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 17.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 17.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 16.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 16.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 16.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 16.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 16.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 16.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 16.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 16.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 15.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 15.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 15.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 15.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 15.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 14.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 14.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 13.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 13.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 13.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 13.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 13.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 13.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 13.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 13.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 13.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 13.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 13.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 13.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 12.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 12.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 12.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 11.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 11.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 11.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 11.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 11.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 11.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 10.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 10.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 10.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 10.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 10.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 10.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 9.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 9.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 9.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 8.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 8.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 8.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 8.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 8.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 7.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 7.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 5.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 5.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 4.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 4.6
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

196.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 196.4
FF:10158-103A5 76 years, female 196.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

135.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 128.1
Samples: 4

Max nTPM: 166.8
Min nTPM: 88.6
Sample A Female 157.2
Sample B Female 88.6
Sample C Male 166.8
Sample D Male 99.6
Midbrain
nTPM: 135.6
Samples: 4

Max nTPM: 185.6
Min nTPM: 97.2
Sample A Female 97.2
Sample B Female 125.8
Sample C Male 185.6
Sample D Male 133.9
Periaqueductal gray
nTPM: 105.9
Samples: 3

Max nTPM: 114.9
Min nTPM: 88.9
Sample B Female 114.9
Sample C Male 113.8
Sample D Male 88.9
Superior colliculi
nTPM: 133.7
Samples: 4

Max nTPM: 195.3
Min nTPM: 63.0
Sample A Female 133.9
Sample B Female 63.0
Sample C Male 195.3
Sample D Male 142.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

86.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 86.3
Samples: 4

Max nTPM: 93.8
Min nTPM: 73.4
Sample A Male 73.4
Sample B Male 90.9
Sample C Female 93.8
Sample D Female 87.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

6.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.8
74641219 Antisense, RP_060220_05_G09, Mouse strain C57BL/6J (56 days, male) 11.9
69134426 Antisense, RP_050321_02_H06, Mouse strain C57BL/6J (56 days, male) 5.5
71209892 Antisense, RP_050810_03_A05, Mouse strain C57BL/6J (56 days, male) 3.0

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by the Knut & Alice Wallenberg Foundation.


contact@proteinatlas.org