Expression of MT-ND2 in urothelial cancer

BLADDER UROTHELIAL CARCINOMA (TCGA) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

MT-ND2 is not prognostic in Bladder Urothelial Carcinoma (TCGA)

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 5294.99

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

5-year survival highⁱ N/A

5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average pTPM

8304.5

Number of samples

169

Samples

Sample	Description	pTPM
TCGA-ZF-A9R0-01A	82 years, male, white, stage:Stage III, dead, 680 days	44817.4
TCGA-XF-A8HG-01A	69 years, male, white, stage:Stage III, dead, 467 days	37901.7
TCGA-G2-A2EC-01A	58 years, female, black or african american, stage:Stage II, dead, 696 days	30747.5
TCGA-XF-A8HH-01A	61 years, female, white, stage:Stage IV, dead, 57 days	27472.3
TCGA-XF-A9SH-01A	65 years, female, asian, stage:Stage II, dead, 1971 days	26221.4
TCGA-E7-A4XJ-01A	66 years, male, asian, stage:Stage II, dead, 68 days	25883.3
TCGA-FD-A5BV-01A	47 years, female, white, stage:Stage III, dead, 163 days	24062.8
TCGA-ZF-A9R9-01A	58 years, male, white, stage:Stage IV, dead, 864 days	23520.4
TCGA-DK-A3IK-01A	87 years, male, white, stage:Stage IV, dead, 146 days	22781.0
TCGA-CU-A0YO-01A	84 years, male, white, stage:Stage IV, dead, 149 days	22583.6
TCGA-XF-A8HF-01A	80 years, male, white, stage:Stage III, dead, 2954 days	21441.0
TCGA-XF-A9SP-01A	59 years, male, white, stage:Stage III, dead, 454 days	20148.6
TCGA-GV-A3QH-01A	67 years, male, white, stage:Stage II, dead, 258 days	20023.0
TCGA-FD-A62O-01A	74 years, male, white, stage:Stage IV, dead, 216 days	19039.3
TCGA-GU-A42R-01A	68 years, male, white, stage:Stage IV, dead, 577 days	18535.3
TCGA-CF-A9FL-01A	85 years, male, asian, stage:Stage III, dead, 565 days	17808.7
TCGA-FD-A3SS-01A	66 years, male, white, stage:Stage IV, dead, 391 days	17015.5
TCGA-K4-A4AC-01A	83 years, male, white, stage:Stage II, dead, 278 days	16560.9
TCGA-BT-A3PK-01A	80 years, male, white, stage:Stage II, dead, 303 days	16293.8
TCGA-BL-A3JM-01A	62 years, male, white, stage:Stage III, dead, 205 days	16274.6
TCGA-4Z-AA7N-01A	65 years, male, white, stage:Stage III, dead, 1367 days	16092.9
TCGA-4Z-AA7R-01A	73 years, male, black or african american, stage:Stage IV, dead, 522 days	15897.0
TCGA-CU-A0YR-01A	83 years, male, white, stage:Stage IV, dead, 460 days	15319.9
TCGA-XF-AAMX-01A	87 years, female, black or african american, stage:Stage III, dead, 206 days	14833.8
TCGA-FJ-A3ZE-01A	65 years, male, white, stage:Stage IV, dead, 324 days	14686.4
TCGA-FJ-A3Z9-01A	72 years, male, white, stage:'--, dead, 385 days	14555.4
TCGA-DK-AA6W-01A	78 years, male, white, stage:Stage II, dead, 415 days	14328.2
TCGA-CU-A5W6-01A	70 years, male, white, stage:Stage III, dead, 56 days	13830.8
TCGA-FD-A6TI-01A	73 years, male, white, stage:Stage IV, dead, 294 days	13681.8
TCGA-GV-A3QF-01A	79 years, male, white, stage:Stage IV, dead, 617 days	13300.3
TCGA-DK-AA75-01A	82 years, male, white, stage:Stage III, dead, 340 days	13124.4
TCGA-ZF-A9R3-01A	53 years, female, white, stage:Stage II, dead, 949 days	13095.6
TCGA-2F-A9KO-01A	63 years, male, white, stage:Stage IV, dead, 734 days	13089.0
TCGA-BT-A2LB-01A	73 years, female, white, stage:Stage III, dead, 492 days	12738.4
TCGA-FD-A6TG-01A	73 years, male, white, stage:Stage IV, dead, 93 days	12473.5
TCGA-XF-AAN0-01A	68 years, male, white, stage:Stage IV, dead, 1718 days	11529.1
TCGA-XF-A8HC-01A	79 years, male, asian, stage:Stage IV, dead, 200 days	11465.1
TCGA-XF-AAN1-01A	75 years, female, stage:Stage III, dead, 941 days	11461.1
TCGA-XF-A8HI-01A	57 years, female, white, stage:Stage IV, dead, 544 days	11456.9
TCGA-G2-A2EL-01A	77 years, male, white, stage:Stage II, dead, 819 days	11426.3
TCGA-C4-A0F7-01A	77 years, male, stage:Stage IV, dead, 62 days	11386.9
TCGA-FD-A3SL-01A	60 years, male, white, stage:Stage IV, dead, 712 days	11192.6
TCGA-FD-A3SM-01A	70 years, male, white, stage:Stage IV, dead, 547 days	10636.5
TCGA-FD-A3SJ-01A	59 years, male, white, stage:Stage IV, dead, 739 days	10483.1
TCGA-BT-A20W-01A	71 years, male, white, stage:Stage II, dead, 254 days	10337.2
TCGA-DK-A2I2-01A	63 years, female, white, stage:Stage IV, dead, 237 days	9981.0
TCGA-2F-A9KW-01A	67 years, female, white, stage:Stage III, dead, 254 days	9849.1
TCGA-XF-A9SV-01A	82 years, male, white, stage:Stage IV, dead, 388 days	9730.0
TCGA-BT-A0YX-01A	70 years, female, white, stage:Stage III, dead, 400 days	9629.3
TCGA-XF-A9SK-01A	65 years, male, white, stage:Stage IV, dead, 486 days	9450.5
TCGA-4Z-AA82-01A	59 years, male, black or african american, stage:Stage IV, dead, 1556 days	9356.8
TCGA-CF-A47T-01A	58 years, female, asian, stage:Stage II, dead, 385 days	9279.6
TCGA-BT-A20J-01A	75 years, male, white, stage:Stage II, dead, 579 days	9004.5
TCGA-5N-A9KM-01A	73 years, female, white, stage:Stage III, dead, 530 days	8972.1
TCGA-DK-A3IL-01A	79 years, female, white, stage:Stage IV, dead, 413 days	8918.7
TCGA-GV-A3JV-01A	66 years, male, white, stage:Stage IV, dead, 434 days	8880.9
TCGA-BT-A20N-01A	72 years, male, stage:Stage III, dead, 795 days	8862.8
TCGA-XF-AAMJ-01A	70 years, male, asian, stage:Stage III, dead, 1670 days	8838.3
TCGA-ZF-AA4T-01A	65 years, male, white, stage:Stage IV, dead, 599 days	8514.2
TCGA-BT-A3PH-01A	76 years, male, white, stage:Stage IV, dead, 142 days	8317.9
TCGA-HQ-A5NE-01A	57 years, male, stage:Stage III, dead, 370 days	8300.8
TCGA-BT-A20Q-01A	73 years, male, white, stage:Stage IV, dead, 593 days	8209.1
TCGA-GU-A42P-01A	72 years, male, white, stage:Stage IV, dead, 332 days	7946.6
TCGA-BT-A2LD-01A	78 years, female, white, stage:Stage IV, dead, 623 days	7678.3
TCGA-G2-A3IE-01A	51 years, male, white, stage:Stage II, dead, 612 days	7653.5
TCGA-4Z-AA7Q-01A	79 years, male, white, stage:Stage III, dead, 510 days	7583.2
TCGA-GC-A3BM-01A	70 years, male, white, stage:Stage II, dead, 651 days	7248.0
TCGA-GU-AATQ-01A	68 years, male, white, stage:Stage III, dead, 213 days	7104.0
TCGA-XF-AAMW-01A	79 years, female, white, stage:Stage IV, dead, 253 days	7048.0
TCGA-DK-A3IQ-01A	74 years, male, white, stage:Stage III, dead, 539 days	6890.9
TCGA-FD-A3SQ-01A	62 years, male, white, stage:Stage IV, dead, 1423 days	6679.2
TCGA-DK-A1A3-01A	60 years, male, white, stage:Stage IV, dead, 665 days	6547.9
TCGA-CU-A0YN-01A	60 years, male, white, stage:Stage III, dead, 393 days	6525.5
TCGA-XF-A9SL-01A	69 years, male, white, stage:Stage IV, dead, 2020 days	6476.5
TCGA-E5-A4TZ-01A	64 years, male, white, stage:Stage IV, dead, 467 days	6403.4
TCGA-E7-A541-01A	66 years, male, white, stage:Stage II, dead, 778 days	6312.7
TCGA-BT-A20T-01A	63 years, male, white, stage:Stage IV, dead, 453 days	6304.7
TCGA-DK-AA6Q-01A	61 years, female, white, stage:Stage IV, dead, 413 days	6228.9
TCGA-UY-A78K-01A	60 years, male, white, stage:Stage IV, dead, 536 days	6213.0
TCGA-SY-A9G0-01A	82 years, male, white, stage:Stage IV, dead, 1008 days	5961.7
TCGA-ZF-AA4N-01A	74 years, male, white, stage:Stage II, dead, 88 days	5948.1
TCGA-UY-A78N-01A	80 years, male, white, stage:Stage IV, dead, 2641 days	5830.7
TCGA-2F-A9KP-01A	66 years, male, white, stage:Stage IV, dead, 364 days	5816.0
TCGA-DK-A3IU-01A	58 years, male, white, stage:Stage II, dead, 706 days	5790.4
TCGA-ZF-AA4U-01A	70 years, male, white, stage:Stage III, dead, 262 days	5783.0
TCGA-ZF-AA52-01A	70 years, male, white, stage:Stage III, dead, 1077 days	5708.6
TCGA-FD-A62P-01A	76 years, male, white, stage:Stage II, dead, 191 days	5553.3
TCGA-BT-A20X-01A	56 years, male, white, stage:Stage IV, dead, 251 days	5542.6
TCGA-XF-AAMT-01A	75 years, female, white, stage:Stage IV, dead, 90 days	5533.2
TCGA-XF-A9SU-01A	74 years, female, white, stage:Stage IV, dead, 182 days	5510.4
TCGA-G2-A2ES-01A	85 years, male, white, stage:Stage II, dead, 1004 days	5503.9
TCGA-FD-A6TF-01A	80 years, female, white, stage:Stage IV, dead, 69 days	5422.1
TCGA-BT-A20P-01A	81 years, female, white, stage:Stage III, dead, 544 days	5415.8
TCGA-XF-AAMZ-01A	81 years, female, white, stage:Stage IV, dead, 1348 days	5399.6
TCGA-UY-A78M-01A	81 years, female, asian, stage:Stage IV, dead, 690 days	5366.9
TCGA-ZF-A9RE-01A	78 years, female, white, stage:Stage II, dead, 106 days	5337.4
TCGA-2F-A9KR-01A	59 years, female, stage:Stage III, dead, 3183 days	5333.0
TCGA-BT-A0S7-01A	75 years, male, white, stage:Stage III, dead, 200 days	5256.9
TCGA-FD-A6TD-01A	77 years, male, white, stage:Stage III, dead, 386 days	5234.4
TCGA-XF-AAN8-01A	74 years, female, white, stage:Stage III, dead, 118 days	5220.1
TCGA-FD-A3B7-01A	66 years, male, black or african american, stage:Stage III, dead, 122 days	5207.6
TCGA-YC-A9TC-01A	71 years, male, white, stage:Stage IV, dead, 20 days	5179.1
TCGA-E7-A3X6-01A	70 years, male, white, stage:Stage II, dead, 904 days	5164.8
TCGA-5N-A9KI-01A	76 years, female, white, stage:Stage III, dead, 76 days	5073.5
TCGA-GV-A40E-01A	75 years, male, white, stage:Stage II, dead, 261 days	5062.1
TCGA-FD-A3B5-01A	86 years, male, black or african american, stage:Stage IV, dead, 272 days	4936.5
TCGA-4Z-AA81-01A	80 years, male, white, stage:Stage II, dead, 1270 days	4905.5
TCGA-XF-A9ST-01A	68 years, male, white, stage:Stage III, dead, 128 days	4884.2
TCGA-FD-A3SO-01A	68 years, male, white, stage:Stage IV, dead, 168 days	4812.6
TCGA-FD-A5C0-01A	61 years, male, white, stage:Stage IV, dead, 550 days	4784.2
TCGA-CU-A72E-01A	76 years, male, white, stage:Stage IV, dead, 413 days	4759.9
TCGA-BT-A20V-01A	59 years, female, black or african american, stage:Stage IV, dead, 154 days	4640.8
TCGA-DK-A1AB-01A	74 years, female, white, stage:Stage IV, dead, 508 days	4583.4
TCGA-XF-A9SW-01A	85 years, male, white, stage:Stage IV, dead, 362 days	4480.7
TCGA-FD-A43Y-01A	65 years, male, white, stage:Stage III, dead, 474 days	4475.7
TCGA-GU-A767-01A	81 years, male, white, stage:Stage IV, dead, 144 days	4425.3
TCGA-C4-A0EZ-01A	69 years, female, stage:Stage IV, dead, 273 days	4342.6
TCGA-DK-A3X2-01A	85 years, male, white, stage:Stage IV, dead, 547 days	4291.4
TCGA-GC-A3I6-01A	45 years, male, white, stage:Stage III, dead, 630 days	4257.2
TCGA-HQ-A5ND-01A	78 years, male, stage:Stage IV, dead, 274 days	4129.9
TCGA-K4-A5RI-01A	67 years, female, white, stage:Stage III, dead, 356 days	4054.3
TCGA-GU-A42Q-01A	67 years, male, white, stage:Stage III, dead, 344 days	4029.8
TCGA-ZF-A9RN-01A	67 years, female, white, stage:Stage III, dead, 615 days	4004.0
TCGA-FD-A5BZ-01A	77 years, female, white, stage:Stage IV, dead, 835 days	4003.3
TCGA-E7-A97P-01A	73 years, male, asian, stage:Stage II, dead, 437 days	3906.2
TCGA-XF-A9SZ-01A	79 years, male, white, stage:Stage IV, dead, 859 days	3842.1
TCGA-XF-AAME-01A	64 years, female, white, stage:Stage II, dead, 2828 days	3821.6
TCGA-FD-A3B3-01A	74 years, female, white, stage:Stage III, dead, 974 days	3747.4
TCGA-DK-A1A5-01A	79 years, male, white, stage:Stage II, dead, 65 days	3713.0
TCGA-XF-AAML-01A	75 years, male, white, stage:Stage II, dead, 232 days	3658.5
TCGA-FD-A3B6-01A	75 years, male, white, stage:Stage II, dead, 1005 days	3636.5
TCGA-DK-A3IN-01A	72 years, male, white, stage:Stage III, dead, 250 days	3601.9
TCGA-XF-AAN4-01A	77 years, female, white, stage:Stage III, dead, 823 days	3561.6
TCGA-XF-AAN2-01A	73 years, male, white, stage:Stage II, dead, 1869 days	3530.3
TCGA-XF-A9SJ-01A	83 years, male, white, stage:Stage IV, dead, 98 days	3510.2
TCGA-XF-AAN7-01A	60 years, male, white, stage:Stage IV, dead, 565 days	3498.5
TCGA-ZF-AA4R-01A	67 years, male, white, stage:Stage IV, dead, 1036 days	3430.7
TCGA-FD-A5BX-01A	82 years, male, white, stage:Stage IV, dead, 173 days	3360.8
TCGA-4Z-AA7S-01A	66 years, male, black or african american, stage:Stage III, dead, 1064 days	3204.9
TCGA-GU-A762-01A	87 years, male, white, stage:Stage IV, dead, 232 days	3169.6
TCGA-4Z-AA80-01A	73 years, male, white, stage:Stage II, dead, 19 days	3117.0
TCGA-FD-A3B4-01A	55 years, female, black or african american, stage:Stage III, dead, 510 days	3065.6
TCGA-4Z-AA86-01A	66 years, male, black or african american, stage:Stage IV, dead, 311 days	3056.9
TCGA-FD-A6TH-01A	63 years, male, white, stage:Stage IV, dead, 131 days	2995.8
TCGA-G2-A3IB-01A	66 years, male, black or african american, stage:Stage II, dead, 220 days	2846.8
TCGA-FD-A3N5-01A	69 years, male, black or african american, stage:Stage II, dead, 685 days	2691.1
TCGA-GU-AATO-01A	75 years, male, white, stage:Stage IV, dead, 324 days	2681.9
TCGA-ZF-AA56-01A	79 years, female, white, stage:Stage III, dead, 259 days	2666.5
TCGA-DK-A3IM-01A	76 years, male, white, stage:Stage III, dead, 248 days	2537.9
TCGA-XF-A9T8-01A	64 years, male, white, stage:Stage III, dead, 418 days	2509.4
TCGA-G2-A2EO-01A	69 years, male, white, stage:Stage III, dead, 1804 days	2337.1
TCGA-FD-A62S-01A	60 years, female, black or african american, stage:Stage III, dead, 406 days	2208.2
TCGA-BT-A20U-01A	70 years, female, white, stage:Stage III, dead, 455 days	2167.3
TCGA-XF-AAMH-01A	80 years, male, white, stage:Stage IV, dead, 344 days	2049.6
TCGA-ZF-AA5N-01A	62 years, female, white, stage:Stage IV, dead, 168 days	1947.9
TCGA-DK-A2HX-01A	80 years, female, white, stage:Stage IV, dead, 1420 days	1928.2
TCGA-XF-A9T2-01A	54 years, male, white, stage:Stage III, dead, 575 days	1795.9
TCGA-ZF-A9RD-01A	75 years, female, white, stage:Stage IV, dead, 408 days	1760.8
TCGA-FD-A3SR-01A	68 years, male, white, stage:Stage IV, dead, 602 days	1727.6
TCGA-S5-A6DX-01A	83 years, male, white, stage:Stage IV, dead, 56 days	1642.9
TCGA-BT-A20O-01A	75 years, male, white, stage:Stage III, dead, 370 days	1453.1
TCGA-FJ-A871-01A	49 years, male, white, stage:Stage III, dead, 272 days	1380.9
TCGA-DK-AA6L-01A	48 years, male, white, stage:Stage IV, dead, 1163 days	1360.1
TCGA-XF-A9SX-01A	63 years, female, white, stage:Stage IV, dead, 719 days	1352.7
TCGA-G2-AA3C-01A	66 years, male, white, stage:Stage IV, dead, 211 days	1211.9
TCGA-FD-A5BT-01A	84 years, male, white, stage:Stage III, dead, 328 days	1055.6
TCGA-ZF-AA54-01A	71 years, male, white, stage:Stage III, dead, 590 days	948.7
TCGA-BL-A13I-01A	57 years, female, white, stage:Stage III, dead, 223 days	260.4
TCGA-BL-A13J-01A	65 years, male, white, stage:Stage IV, dead, 81 days	69.0
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UROTHELIAL CANCER - Protein expressionⁱ

Pending cancer tissue analysis