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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:77.1 nTPM
HPA Brain:187.2 nTPM
GTEx:77.1 nTPM
FANTOM5:38.5 Scaled Tags Per Million
Pig:117.9 nTPM
Mouse:232.5 nTPM
Allen mouse:17.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

187.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 170.2
2666 Male, age 74, left hemisphere 238.1
2586 Male, age 75, left hemisphere 207.0
1827 Male, age 72, unknown 200.6
2019 Male, age 18, unknown 171.2
2219 Male, age 76, both hemispheres 168.8
2828 Female, age 72, unknown 165.0
2411 Female, age 72, unknown 155.7
1870 Female, age 42, unknown 137.1
1833 Male, age 53, unknown 133.7
1830 Male, age 51, unknown 124.2
Dorsal raphe nucleus
nTPM: 144.3
1828 Male, age 53, unknown 159.1
2047 Male, age 72, unknown 154.7
2298 Female, age 72, unknown 154.7
2750 Male, age 76, both hemispheres 142.5
2016 Female, age 72, unknown 110.4
Inferior colliculus
nTPM: 164.2
2097 Female, age 72, unknown 190.7
1848 Female, age 42, unknown 161.7
1890 Male, age 53, unknown 158.4
2849 Male, age 72, unknown 145.8
Median raphe nucleus
nTPM: 166.3
2220 Male, age 76, midline 166.3
Periaquaductal grey, anterior
nTPM: 187.2
1947 Male, age 18, unknown 196.7
1795 Male, age 51, unknown 190.5
2502 Female, age 75, unknown 174.2
Periaquaductal grey, dorsal
nTPM: 135.5
1840 Male, age 53, unknown 143.6
1831 Male, age 72, unknown 141.7
2464 Female, age 72, unknown 137.2
2850 Male, age 76, both hemispheres 119.5
Periaquaductal grey, lateral
nTPM: 116.6
2053 Male, age 18, unknown 139.3
2140 Male, age 76, both hemispheres 118.1
2272 Male, age 74, both hemispheres 92.3
Pretectal area
nTPM: 178.8
1816 Male, age 51, unknown 270.5
2007 Male, age 72, unknown 240.5
1817 Female, age 42, unknown 226.7
1944 Female, age 72, unknown 224.5
1815 Male, age 53, unknown 194.8
2667 Female, age 75, unknown 169.2
2825 Male, age 18, unknown 142.7
2407 Male, age 75, both hemispheres 137.5
2224 Female, age 72, unknown 136.3
2316 Male, age 76, right hemisphere 132.3
2273 Male, age 74, both hemispheres 92.2
Red nucleus
nTPM: 143.4
2584 Male, age 75, left hemisphere 169.9
1821 Female, age 72, unknown 165.9
2785 Male, age 18, unknown 160.9
2823 Male, age 76, right hemisphere 149.7
1954 Female, age 42, unknown 147.2
2588 Male, age 74, left hemisphere 144.6
2769 Male, age 72, unknown 138.8
2227 Male, age 72, unknown 135.2
1865 Male, age 51, unknown 131.1
2503 Female, age 72, unknown 129.3
1904 Male, age 53, unknown 126.1
2725 Female, age 75, unknown 121.7
Substantia nigra
nTPM: 178.0
1941 Male, age 53, unknown 229.3
2665 Male, age 74, both hemispheres 224.5
1916 Female, age 42, unknown 223.1
1889 Female, age 72, unknown 207.6
1851 Male, age 51, unknown 180.0
2241 Male, age 72, unknown 164.9
2583 Male, age 75, right hemisphere 161.2
2409 Female, age 72, unknown 143.6
2699 Male, age 18, unknown 123.2
2590 Female, age 75, unknown 122.2
Superior colliculus
nTPM: 177.0
2668 Female, age 75, unknown 304.8
2087 Female, age 72, unknown 207.8
2664 Male, age 75, both hemispheres 195.3
2261 Male, age 18, unknown 193.3
1796 Male, age 53, unknown 183.7
1895 Male, age 76, right hemisphere 177.7
1839 Male, age 51, unknown 151.5
1913 Female, age 42, unknown 123.1
2587 Male, age 74, left hemisphere 120.1
1995 Male, age 72, unknown 112.7
Ventral tegmental area
nTPM: 158.4
2410 Female, age 72, unknown 197.8
2218 Male, age 76, both hemispheres 186.2
1915 Female, age 42, unknown 169.8
1942 Male, age 51, unknown 151.6
2223 Female, age 72, unknown 127.8
2021 Male, age 53, unknown 117.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

77.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 77.1
Samples: 139

Max nTPM: 327.2
Min nTPM: 21.6
Std nTPM: 46.4
Median nTPM: 63.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 327.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 242.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 194.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 178.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 176.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 175.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 170.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 154.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 145.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 144.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 144.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 136.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 133.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 131.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 131.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 127.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 126.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 124.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 123.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 121.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 120.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 119.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 116.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 116.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 115.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 115.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 114.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 113.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 110.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 108.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 108.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 107.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 105.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 102.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 100.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 98.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 98.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 98.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 96.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 96.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 95.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 95.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 95.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 94.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 94.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 94.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 93.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 93.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 92.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 91.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 88.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 87.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 80.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 80.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 79.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 76.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 76.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 75.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 73.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 73.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 72.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 71.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 68.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 68.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 67.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 65.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 65.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 65.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 64.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 63.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 63.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 63.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 61.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 60.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 59.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 58.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 58.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 56.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 56.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 55.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 55.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 54.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 53.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 52.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 52.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 51.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 51.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 50.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 50.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 50.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 50.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 49.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 48.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 47.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 46.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 45.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 45.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 44.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 44.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 44.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 44.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 44.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 43.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 43.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 42.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 41.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 40.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 40.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 39.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 39.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 39.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 38.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 38.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 38.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 37.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 37.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 37.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 35.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 35.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 35.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 35.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 34.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 33.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 33.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 33.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 33.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 32.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 32.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 32.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 30.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 29.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 29.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 28.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 28.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 27.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 26.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 24.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 21.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 21.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

38.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 38.5
FF:10158-103A5 76 years, female 38.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

117.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 118.0
Samples: 4

Max nTPM: 167.1
Min nTPM: 62.4
Sample A Female 167.1
Sample B Female 81.4
Sample C Male 160.9
Sample D Male 62.4
Midbrain
nTPM: 117.3
Samples: 4

Max nTPM: 174.9
Min nTPM: 87.0
Sample A Female 87.0
Sample B Female 87.7
Sample C Male 174.9
Sample D Male 119.7
Periaqueductal gray
nTPM: 80.5
Samples: 3

Max nTPM: 96.0
Min nTPM: 66.6
Sample B Female 79.0
Sample C Male 96.0
Sample D Male 66.6
Superior colliculi
nTPM: 117.4
Samples: 4

Max nTPM: 150.0
Min nTPM: 65.8
Sample A Female 132.8
Sample B Female 65.8
Sample C Male 150.0
Sample D Male 120.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

232.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 232.5
Samples: 4

Max nTPM: 242.2
Min nTPM: 220.5
Sample A Male 220.5
Sample B Male 225.4
Sample C Female 242.2
Sample D Female 241.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

17.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 17.3
583561 Antisense, RP_040831_02_H11, Mouse strain C57BL/6J (56 days, male) 19.7
81599672 Antisense, RP_071219_04_G12, Mouse strain C57BL/6J (56 days, male) 15.0

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