Expression of MT-ATP6 in urothelial cancer

BLADDER UROTHELIAL CARCINOMA (TCGA) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

MT-ATP6 is not prognostic in Bladder Urothelial Carcinoma (TCGA)

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 5834.81

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

5-year survival highⁱ N/A

5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average pTPM

12272.2

Number of samples

169

Samples

Sample	Description	pTPM
TCGA-XF-A8HG-01A	69 years, male, white, stage:Stage III, dead, 467 days	57810.8
TCGA-ZF-A9R0-01A	82 years, male, white, stage:Stage III, dead, 680 days	48001.3
TCGA-DK-A3IK-01A	87 years, male, white, stage:Stage IV, dead, 146 days	42834.0
TCGA-XF-A9SH-01A	65 years, female, asian, stage:Stage II, dead, 1971 days	38087.9
TCGA-XF-A8HF-01A	80 years, male, white, stage:Stage III, dead, 2954 days	33276.4
TCGA-E7-A4XJ-01A	66 years, male, asian, stage:Stage II, dead, 68 days	33011.4
TCGA-CF-A9FL-01A	85 years, male, asian, stage:Stage III, dead, 565 days	31406.8
TCGA-FD-A5BV-01A	47 years, female, white, stage:Stage III, dead, 163 days	31327.6
TCGA-GV-A3QF-01A	79 years, male, white, stage:Stage IV, dead, 617 days	30994.1
TCGA-FJ-A3ZE-01A	65 years, male, white, stage:Stage IV, dead, 324 days	29487.8
TCGA-CU-A0YO-01A	84 years, male, white, stage:Stage IV, dead, 149 days	27630.9
TCGA-FJ-A3Z9-01A	72 years, male, white, stage:'--, dead, 385 days	26463.6
TCGA-GV-A3QH-01A	67 years, male, white, stage:Stage II, dead, 258 days	26364.1
TCGA-XF-A8HH-01A	61 years, female, white, stage:Stage IV, dead, 57 days	24934.1
TCGA-ZF-A9R9-01A	58 years, male, white, stage:Stage IV, dead, 864 days	22786.0
TCGA-4Z-AA7R-01A	73 years, male, black or african american, stage:Stage IV, dead, 522 days	22476.9
TCGA-BT-A3PK-01A	80 years, male, white, stage:Stage II, dead, 303 days	22205.6
TCGA-FD-A3SS-01A	66 years, male, white, stage:Stage IV, dead, 391 days	21959.7
TCGA-G2-A2EC-01A	58 years, female, black or african american, stage:Stage II, dead, 696 days	21694.6
TCGA-CF-A47T-01A	58 years, female, asian, stage:Stage II, dead, 385 days	21540.6
TCGA-FD-A62O-01A	74 years, male, white, stage:Stage IV, dead, 216 days	21387.9
TCGA-4Z-AA7N-01A	65 years, male, white, stage:Stage III, dead, 1367 days	21351.5
TCGA-G2-A2EL-01A	77 years, male, white, stage:Stage II, dead, 819 days	20830.5
TCGA-GU-A42R-01A	68 years, male, white, stage:Stage IV, dead, 577 days	20760.6
TCGA-DK-AA75-01A	82 years, male, white, stage:Stage III, dead, 340 days	20422.0
TCGA-DK-A3IL-01A	79 years, female, white, stage:Stage IV, dead, 413 days	20116.5
TCGA-FD-A6TI-01A	73 years, male, white, stage:Stage IV, dead, 294 days	19484.0
TCGA-GV-A3JV-01A	66 years, male, white, stage:Stage IV, dead, 434 days	18704.1
TCGA-FD-A3SJ-01A	59 years, male, white, stage:Stage IV, dead, 739 days	18702.3
TCGA-XF-A8HI-01A	57 years, female, white, stage:Stage IV, dead, 544 days	18193.1
TCGA-BT-A20W-01A	71 years, male, white, stage:Stage II, dead, 254 days	18103.1
TCGA-2F-A9KO-01A	63 years, male, white, stage:Stage IV, dead, 734 days	17845.8
TCGA-ZF-A9R3-01A	53 years, female, white, stage:Stage II, dead, 949 days	17743.9
TCGA-BT-A3PH-01A	76 years, male, white, stage:Stage IV, dead, 142 days	17596.0
TCGA-CU-A0YR-01A	83 years, male, white, stage:Stage IV, dead, 460 days	17561.4
TCGA-BT-A20Q-01A	73 years, male, white, stage:Stage IV, dead, 593 days	17195.9
TCGA-BT-A20J-01A	75 years, male, white, stage:Stage II, dead, 579 days	17049.7
TCGA-K4-A4AC-01A	83 years, male, white, stage:Stage II, dead, 278 days	16898.9
TCGA-XF-A9SP-01A	59 years, male, white, stage:Stage III, dead, 454 days	16876.9
TCGA-XF-AAN0-01A	68 years, male, white, stage:Stage IV, dead, 1718 days	16861.7
TCGA-GU-A42P-01A	72 years, male, white, stage:Stage IV, dead, 332 days	16539.6
TCGA-BT-A2LB-01A	73 years, female, white, stage:Stage III, dead, 492 days	16469.9
TCGA-C4-A0F7-01A	77 years, male, stage:Stage IV, dead, 62 days	16439.8
TCGA-XF-A8HC-01A	79 years, male, asian, stage:Stage IV, dead, 200 days	16182.3
TCGA-2F-A9KW-01A	67 years, female, white, stage:Stage III, dead, 254 days	16177.4
TCGA-FD-A62P-01A	76 years, male, white, stage:Stage II, dead, 191 days	16105.2
TCGA-GU-AATQ-01A	68 years, male, white, stage:Stage III, dead, 213 days	15708.4
TCGA-BT-A20N-01A	72 years, male, stage:Stage III, dead, 795 days	15473.5
TCGA-BL-A3JM-01A	62 years, male, white, stage:Stage III, dead, 205 days	15435.1
TCGA-FD-A6TG-01A	73 years, male, white, stage:Stage IV, dead, 93 days	14936.4
TCGA-XF-A9SV-01A	82 years, male, white, stage:Stage IV, dead, 388 days	14900.5
TCGA-CU-A72E-01A	76 years, male, white, stage:Stage IV, dead, 413 days	14672.0
TCGA-CU-A5W6-01A	70 years, male, white, stage:Stage III, dead, 56 days	14540.4
TCGA-BT-A0YX-01A	70 years, female, white, stage:Stage III, dead, 400 days	14483.6
TCGA-DK-A3IQ-01A	74 years, male, white, stage:Stage III, dead, 539 days	14443.2
TCGA-FD-A3SM-01A	70 years, male, white, stage:Stage IV, dead, 547 days	14293.1
TCGA-UY-A78M-01A	81 years, female, asian, stage:Stage IV, dead, 690 days	14199.7
TCGA-4Z-AA7Q-01A	79 years, male, white, stage:Stage III, dead, 510 days	14196.5
TCGA-G2-A3IE-01A	51 years, male, white, stage:Stage II, dead, 612 days	13779.2
TCGA-2F-A9KP-01A	66 years, male, white, stage:Stage IV, dead, 364 days	13518.9
TCGA-XF-AAMT-01A	75 years, female, white, stage:Stage IV, dead, 90 days	12469.6
TCGA-DK-A1A3-01A	60 years, male, white, stage:Stage IV, dead, 665 days	12464.0
TCGA-DK-AA6W-01A	78 years, male, white, stage:Stage II, dead, 415 days	12426.5
TCGA-BT-A20X-01A	56 years, male, white, stage:Stage IV, dead, 251 days	12342.2
TCGA-GC-A3BM-01A	70 years, male, white, stage:Stage II, dead, 651 days	12269.6
TCGA-5N-A9KM-01A	73 years, female, white, stage:Stage III, dead, 530 days	12263.1
TCGA-FD-A6TF-01A	80 years, female, white, stage:Stage IV, dead, 69 days	12076.5
TCGA-GU-A42Q-01A	67 years, male, white, stage:Stage III, dead, 344 days	11995.4
TCGA-UY-A78K-01A	60 years, male, white, stage:Stage IV, dead, 536 days	11982.6
TCGA-UY-A78N-01A	80 years, male, white, stage:Stage IV, dead, 2641 days	11894.1
TCGA-HQ-A5NE-01A	57 years, male, stage:Stage III, dead, 370 days	11763.3
TCGA-XF-A9SK-01A	65 years, male, white, stage:Stage IV, dead, 486 days	11696.7
TCGA-ZF-AA4U-01A	70 years, male, white, stage:Stage III, dead, 262 days	11520.7
TCGA-4Z-AA82-01A	59 years, male, black or african american, stage:Stage IV, dead, 1556 days	11185.3
TCGA-DK-AA6Q-01A	61 years, female, white, stage:Stage IV, dead, 413 days	11050.0
TCGA-FD-A3SQ-01A	62 years, male, white, stage:Stage IV, dead, 1423 days	10878.0
TCGA-XF-AAN1-01A	75 years, female, stage:Stage III, dead, 941 days	10876.9
TCGA-DK-A1AB-01A	74 years, female, white, stage:Stage IV, dead, 508 days	10777.2
TCGA-CU-A0YN-01A	60 years, male, white, stage:Stage III, dead, 393 days	10710.4
TCGA-FD-A5C0-01A	61 years, male, white, stage:Stage IV, dead, 550 days	10682.5
TCGA-XF-AAMJ-01A	70 years, male, asian, stage:Stage III, dead, 1670 days	10133.7
TCGA-BT-A2LD-01A	78 years, female, white, stage:Stage IV, dead, 623 days	10054.3
TCGA-FD-A6TD-01A	77 years, male, white, stage:Stage III, dead, 386 days	9942.1
TCGA-SY-A9G0-01A	82 years, male, white, stage:Stage IV, dead, 1008 days	9802.7
TCGA-4Z-AA7S-01A	66 years, male, black or african american, stage:Stage III, dead, 1064 days	9725.9
TCGA-E7-A3X6-01A	70 years, male, white, stage:Stage II, dead, 904 days	9710.9
TCGA-XF-AAMW-01A	79 years, female, white, stage:Stage IV, dead, 253 days	9591.3
TCGA-DK-A1A5-01A	79 years, male, white, stage:Stage II, dead, 65 days	9392.6
TCGA-HQ-A5ND-01A	78 years, male, stage:Stage IV, dead, 274 days	9286.1
TCGA-G2-A2ES-01A	85 years, male, white, stage:Stage II, dead, 1004 days	9141.3
TCGA-ZF-AA4N-01A	74 years, male, white, stage:Stage II, dead, 88 days	9066.6
TCGA-FD-A3B6-01A	75 years, male, white, stage:Stage II, dead, 1005 days	9039.4
TCGA-FD-A3SL-01A	60 years, male, white, stage:Stage IV, dead, 712 days	8911.9
TCGA-E5-A4TZ-01A	64 years, male, white, stage:Stage IV, dead, 467 days	8833.5
TCGA-XF-A9SZ-01A	79 years, male, white, stage:Stage IV, dead, 859 days	8726.3
TCGA-E7-A541-01A	66 years, male, white, stage:Stage II, dead, 778 days	8694.2
TCGA-2F-A9KR-01A	59 years, female, stage:Stage III, dead, 3183 days	8617.9
TCGA-XF-AAMX-01A	87 years, female, black or african american, stage:Stage III, dead, 206 days	8572.2
TCGA-XF-AAN8-01A	74 years, female, white, stage:Stage III, dead, 118 days	8560.0
TCGA-ZF-A9RE-01A	78 years, female, white, stage:Stage II, dead, 106 days	8469.7
TCGA-FD-A3B3-01A	74 years, female, white, stage:Stage III, dead, 974 days	8420.3
TCGA-ZF-AA52-01A	70 years, male, white, stage:Stage III, dead, 1077 days	8243.0
TCGA-E7-A97P-01A	73 years, male, asian, stage:Stage II, dead, 437 days	8212.4
TCGA-5N-A9KI-01A	76 years, female, white, stage:Stage III, dead, 76 days	8038.3
TCGA-DK-A3IU-01A	58 years, male, white, stage:Stage II, dead, 706 days	7850.7
TCGA-BT-A20V-01A	59 years, female, black or african american, stage:Stage IV, dead, 154 days	7783.0
TCGA-K4-A5RI-01A	67 years, female, white, stage:Stage III, dead, 356 days	7752.5
TCGA-ZF-AA4T-01A	65 years, male, white, stage:Stage IV, dead, 599 days	7520.8
TCGA-XF-A9SL-01A	69 years, male, white, stage:Stage IV, dead, 2020 days	7434.8
TCGA-XF-A9SU-01A	74 years, female, white, stage:Stage IV, dead, 182 days	7333.1
TCGA-GU-A767-01A	81 years, male, white, stage:Stage IV, dead, 144 days	7315.3
TCGA-XF-A9ST-01A	68 years, male, white, stage:Stage III, dead, 128 days	7285.6
TCGA-XF-AAN2-01A	73 years, male, white, stage:Stage II, dead, 1869 days	7274.1
TCGA-YC-A9TC-01A	71 years, male, white, stage:Stage IV, dead, 20 days	7174.7
TCGA-GC-A3I6-01A	45 years, male, white, stage:Stage III, dead, 630 days	7050.3
TCGA-FD-A43Y-01A	65 years, male, white, stage:Stage III, dead, 474 days	6860.7
TCGA-BT-A0S7-01A	75 years, male, white, stage:Stage III, dead, 200 days	6828.6
TCGA-DK-A3IN-01A	72 years, male, white, stage:Stage III, dead, 250 days	6769.6
TCGA-ZF-AA4R-01A	67 years, male, white, stage:Stage IV, dead, 1036 days	6757.3
TCGA-ZF-AA56-01A	79 years, female, white, stage:Stage III, dead, 259 days	6756.2
TCGA-FD-A3SO-01A	68 years, male, white, stage:Stage IV, dead, 168 days	6695.8
TCGA-XF-AAMZ-01A	81 years, female, white, stage:Stage IV, dead, 1348 days	6633.0
TCGA-FD-A3B5-01A	86 years, male, black or african american, stage:Stage IV, dead, 272 days	6579.1
TCGA-FD-A3B7-01A	66 years, male, black or african american, stage:Stage III, dead, 122 days	6577.1
TCGA-XF-AAN7-01A	60 years, male, white, stage:Stage IV, dead, 565 days	6509.6
TCGA-G2-A3IB-01A	66 years, male, black or african american, stage:Stage II, dead, 220 days	6344.2
TCGA-C4-A0EZ-01A	69 years, female, stage:Stage IV, dead, 273 days	6286.1
TCGA-XF-AAN4-01A	77 years, female, white, stage:Stage III, dead, 823 days	6086.5
TCGA-GV-A40E-01A	75 years, male, white, stage:Stage II, dead, 261 days	6013.8
TCGA-FD-A5BX-01A	82 years, male, white, stage:Stage IV, dead, 173 days	5907.8
TCGA-XF-AAME-01A	64 years, female, white, stage:Stage II, dead, 2828 days	5873.5
TCGA-4Z-AA81-01A	80 years, male, white, stage:Stage II, dead, 1270 days	5851.0
TCGA-ZF-A9RD-01A	75 years, female, white, stage:Stage IV, dead, 408 days	5818.6
TCGA-XF-AAML-01A	75 years, male, white, stage:Stage II, dead, 232 days	5549.6
TCGA-DK-A2I2-01A	63 years, female, white, stage:Stage IV, dead, 237 days	5486.7
TCGA-G2-A2EO-01A	69 years, male, white, stage:Stage III, dead, 1804 days	5427.7
TCGA-ZF-A9RN-01A	67 years, female, white, stage:Stage III, dead, 615 days	5315.6
TCGA-XF-A9SW-01A	85 years, male, white, stage:Stage IV, dead, 362 days	5283.0
TCGA-XF-A9SJ-01A	83 years, male, white, stage:Stage IV, dead, 98 days	5281.2
TCGA-BT-A20P-01A	81 years, female, white, stage:Stage III, dead, 544 days	5259.2
TCGA-XF-A9T8-01A	64 years, male, white, stage:Stage III, dead, 418 days	5098.7
TCGA-GU-A762-01A	87 years, male, white, stage:Stage IV, dead, 232 days	5060.7
TCGA-XF-AAMH-01A	80 years, male, white, stage:Stage IV, dead, 344 days	5057.6
TCGA-FD-A5BZ-01A	77 years, female, white, stage:Stage IV, dead, 835 days	5018.0
TCGA-BT-A20T-01A	63 years, male, white, stage:Stage IV, dead, 453 days	4917.2
TCGA-DK-A3IM-01A	76 years, male, white, stage:Stage III, dead, 248 days	4697.8
TCGA-BT-A20U-01A	70 years, female, white, stage:Stage III, dead, 455 days	4675.7
TCGA-GU-AATO-01A	75 years, male, white, stage:Stage IV, dead, 324 days	4656.1
TCGA-4Z-AA80-01A	73 years, male, white, stage:Stage II, dead, 19 days	4503.6
TCGA-FJ-A871-01A	49 years, male, white, stage:Stage III, dead, 272 days	4447.0
TCGA-FD-A6TH-01A	63 years, male, white, stage:Stage IV, dead, 131 days	4151.9
TCGA-DK-A3X2-01A	85 years, male, white, stage:Stage IV, dead, 547 days	4063.2
TCGA-ZF-AA5N-01A	62 years, female, white, stage:Stage IV, dead, 168 days	3999.4
TCGA-BT-A20O-01A	75 years, male, white, stage:Stage III, dead, 370 days	3831.9
TCGA-4Z-AA86-01A	66 years, male, black or african american, stage:Stage IV, dead, 311 days	3658.5
TCGA-XF-A9T2-01A	54 years, male, white, stage:Stage III, dead, 575 days	3621.0
TCGA-FD-A3N5-01A	69 years, male, black or african american, stage:Stage II, dead, 685 days	3567.0
TCGA-FD-A3B4-01A	55 years, female, black or african american, stage:Stage III, dead, 510 days	3507.5
TCGA-FD-A62S-01A	60 years, female, black or african american, stage:Stage III, dead, 406 days	3330.2
TCGA-DK-A2HX-01A	80 years, female, white, stage:Stage IV, dead, 1420 days	2875.0
TCGA-S5-A6DX-01A	83 years, male, white, stage:Stage IV, dead, 56 days	2448.3
TCGA-G2-AA3C-01A	66 years, male, white, stage:Stage IV, dead, 211 days	2059.3
TCGA-XF-A9SX-01A	63 years, female, white, stage:Stage IV, dead, 719 days	2028.2
TCGA-FD-A3SR-01A	68 years, male, white, stage:Stage IV, dead, 602 days	1885.2
TCGA-DK-AA6L-01A	48 years, male, white, stage:Stage IV, dead, 1163 days	1841.7
TCGA-ZF-AA54-01A	71 years, male, white, stage:Stage III, dead, 590 days	1647.7
TCGA-FD-A5BT-01A	84 years, male, white, stage:Stage III, dead, 328 days	1116.9
TCGA-BL-A13I-01A	57 years, female, white, stage:Stage III, dead, 223 days	590.9
TCGA-BL-A13J-01A	65 years, male, white, stage:Stage IV, dead, 81 days	149.8
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UROTHELIAL CANCER - Protein expressionⁱ

Pending cancer tissue analysis