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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:13.8 nTPM
HPA Brain:100.7 nTPM
GTEx:13.8 nTPM
FANTOM5:4.0 Scaled Tags Per Million
Pig:51.7 nTPM
Mouse:47.8 nTPM
Allen mouse:2.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

100.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 57.1
2219 Male, age 76, both hemispheres 98.6
2666 Male, age 74, left hemisphere 75.6
1827 Male, age 72, unknown 66.5
2411 Female, age 72, unknown 63.4
2586 Male, age 75, left hemisphere 63.2
2828 Female, age 72, unknown 50.1
1870 Female, age 42, unknown 47.0
1833 Male, age 53, unknown 42.6
1830 Male, age 51, unknown 40.3
2019 Male, age 18, unknown 24.2
Dorsal raphe nucleus
nTPM: 63.0
2298 Female, age 72, unknown 85.6
2047 Male, age 72, unknown 80.3
2750 Male, age 76, both hemispheres 60.4
1828 Male, age 53, unknown 48.8
2016 Female, age 72, unknown 39.7
Inferior colliculus
nTPM: 54.7
2097 Female, age 72, unknown 68.0
2849 Male, age 72, unknown 57.1
1848 Female, age 42, unknown 47.5
1890 Male, age 53, unknown 46.1
Median raphe nucleus
nTPM: 100.7
2220 Male, age 76, midline 100.7
Periaquaductal grey, anterior
nTPM: 79.2
2502 Female, age 75, unknown 99.3
1795 Male, age 51, unknown 79.2
1947 Male, age 18, unknown 58.9
Periaquaductal grey, dorsal
nTPM: 55.8
1840 Male, age 53, unknown 65.9
2464 Female, age 72, unknown 55.9
2850 Male, age 76, both hemispheres 55.1
1831 Male, age 72, unknown 46.2
Periaquaductal grey, lateral
nTPM: 46.5
2053 Male, age 18, unknown 55.9
2140 Male, age 76, both hemispheres 54.7
2272 Male, age 74, both hemispheres 29.1
Pretectal area
nTPM: 55.0
2224 Female, age 72, unknown 82.9
1816 Male, age 51, unknown 72.6
1944 Female, age 72, unknown 68.7
2825 Male, age 18, unknown 65.2
2007 Male, age 72, unknown 55.4
2667 Female, age 75, unknown 54.2
2316 Male, age 76, right hemisphere 50.8
1815 Male, age 53, unknown 48.9
1817 Female, age 42, unknown 46.1
2407 Male, age 75, both hemispheres 37.7
2273 Male, age 74, both hemispheres 22.9
Red nucleus
nTPM: 20.7
2584 Male, age 75, left hemisphere 56.5
2785 Male, age 18, unknown 33.4
1954 Female, age 42, unknown 23.2
1821 Female, age 72, unknown 22.6
2769 Male, age 72, unknown 19.8
2227 Male, age 72, unknown 19.1
2503 Female, age 72, unknown 17.1
1865 Male, age 51, unknown 13.7
1904 Male, age 53, unknown 13.5
2588 Male, age 74, left hemisphere 11.8
2725 Female, age 75, unknown 9.3
2823 Male, age 76, right hemisphere 8.7
Substantia nigra
nTPM: 59.2
1941 Male, age 53, unknown 93.6
1916 Female, age 42, unknown 84.7
2665 Male, age 74, both hemispheres 82.3
1851 Male, age 51, unknown 67.7
2241 Male, age 72, unknown 60.0
2699 Male, age 18, unknown 50.1
1889 Female, age 72, unknown 49.7
2409 Female, age 72, unknown 42.9
2583 Male, age 75, right hemisphere 37.9
2590 Female, age 75, unknown 23.2
Superior colliculus
nTPM: 65.3
2668 Female, age 75, unknown 186.6
1796 Male, age 53, unknown 69.1
2664 Male, age 75, both hemispheres 65.4
2261 Male, age 18, unknown 63.6
1895 Male, age 76, right hemisphere 60.3
1839 Male, age 51, unknown 54.6
2087 Female, age 72, unknown 48.3
2587 Male, age 74, left hemisphere 44.4
1913 Female, age 42, unknown 31.8
1995 Male, age 72, unknown 29.2
Ventral tegmental area
nTPM: 64.7
2218 Male, age 76, both hemispheres 79.1
1915 Female, age 42, unknown 70.0
2021 Male, age 53, unknown 67.2
1942 Male, age 51, unknown 66.2
2410 Female, age 72, unknown 55.9
2223 Female, age 72, unknown 49.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

13.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 13.8
Samples: 139

Max nTPM: 89.9
Min nTPM: 0.0
Std nTPM: 14.4
Median nTPM: 8.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 89.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 74.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 46.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 45.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 43.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 42.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 42.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 39.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 36.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 35.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 34.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 33.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 33.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 33.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 33.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 32.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 32.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 32.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 29.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 29.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 27.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 26.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 26.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 25.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 23.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 23.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 21.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 21.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 21.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 21.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 21.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 20.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 20.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 20.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 19.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 19.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 19.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 19.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 19.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 19.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 19.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 19.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 18.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 18.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 18.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 18.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 18.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 18.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 17.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 16.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 15.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 15.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 15.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 14.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 14.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 13.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 13.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 13.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 12.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 12.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 12.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 10.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 10.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 10.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 10.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 10.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 9.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 9.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 8.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 8.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 8.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 8.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 7.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 7.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 7.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 7.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 6.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 6.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 6.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 6.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 6.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 5.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 5.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 5.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 5.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 5.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 5.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 5.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 5.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 4.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 4.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 4.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 4.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 4.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 4.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 3.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 3.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 3.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 3.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 3.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 3.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 3.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 2.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 2.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 2.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 2.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 2.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 2.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 2.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 2.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 2.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 2.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 2.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 2.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 2.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 2.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 2.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 2.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 0.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 0.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 0.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 0.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 0.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 0.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 0.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 0.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 0.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 0.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

4.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 4.0
FF:10158-103A5 76 years, female 4.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

51.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 45.7
Samples: 4

Max nTPM: 75.5
Min nTPM: 8.2
Sample A Female 64.0
Sample B Female 35.2
Sample C Male 75.5
Sample D Male 8.2
Midbrain
nTPM: 51.7
Samples: 4

Max nTPM: 113.3
Min nTPM: 10.3
Sample A Female 10.3
Sample B Female 28.4
Sample C Male 113.3
Sample D Male 54.9
Periaqueductal gray
nTPM: 33.6
Samples: 3

Max nTPM: 50.8
Min nTPM: 24.3
Sample B Female 24.3
Sample C Male 50.8
Sample D Male 25.8
Superior colliculi
nTPM: 47.0
Samples: 4

Max nTPM: 75.5
Min nTPM: 23.9
Sample A Female 39.1
Sample B Female 23.9
Sample C Male 75.5
Sample D Male 49.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

47.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 47.8
Samples: 4

Max nTPM: 51.3
Min nTPM: 39.4
Sample A Male 39.4
Sample B Male 50.5
Sample C Female 51.3
Sample D Female 50.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.0
79591595 Antisense, RP_071204_04_D07, Mouse strain C57BL/6J (56 days, male) 4.9
80342072 Antisense, RP_071204_04_D07, Mouse strain C57BL/6J (56 days, male) 3.4
620 Antisense, RP_Baylor_102880, Mouse strain C57BL/6J (56 days, male) 1.1
621 Antisense, RP_Baylor_102880, Mouse strain C57BL/6J (56 days, male) 0.9
622 Sense, RPS_Baylor_37010, Mouse strain C57BL/6J (56 days, male) 0.0

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