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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
95.6
nTPM
HPA:
15.5
nTPM
GTEx:
95.6
nTPM
FANTOM5:
18.1
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA043032
Antibody HPA048123
Cholangiocytes
Not detected
Not detected
Hepatocytes
Not detected
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
15.5
Female, age 60
Liver sample 21 nTPM: 19.3
Male, age 54
Liver sample 23 nTPM: 19.9
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 16.8
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 12.3
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 12.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 13.2
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 12.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 18.3
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 17.4
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 13.4
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
95.6
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 95.6
Samples: 226
Max nTPM: 219.7
Min nTPM: 21.3
Std nTPM: 25.5
Median nTPM: 93.1
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
219.7
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
191.4
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
167.3
GTEX-S32W-1926-SM-4AD63
50-59 years, female
159.5
GTEX-12696-0826-SM-5EGGE
60-69 years, male
157.3
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
153.5
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
148.7
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
145.4
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
142.4
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
140.3
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
139.0
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
139.0
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
137.1
GTEX-O5YV-0726-SM-EV798
60-69 years, female
136.9
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
135.2
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
135.1
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
134.7
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
133.1
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
130.6
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
130.3
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
129.9
GTEX-RU72-1426-SM-46MUF
50-59 years, female
129.3
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
127.1
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
126.7
GTEX-REY6-1226-SM-48FDR
60-69 years, male
126.3
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
124.9
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
124.5
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
123.7
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
123.4
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
122.3
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
122.2
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
121.0
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
120.8
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
120.7
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
120.5
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
120.4
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
119.8
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
118.2
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
116.5
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
115.9
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
115.9
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
114.8
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
114.5
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
114.4
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
114.1
GTEX-YECK-1926-SM-4W21H
60-69 years, male
112.9
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
112.7
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
112.6
GTEX-18465-1626-SM-7LG6N
50-59 years, male
112.4
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
111.8
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
111.7
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
110.7
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
110.7
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
109.9
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
109.7
GTEX-P78B-1326-SM-3P611
40-49 years, female
109.4
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
109.2
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
109.0
GTEX-13113-1326-SM-5GCOI
60-69 years, female
108.8
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
108.8
GTEX-14E7W-1526-SM-6871X
70-79 years, male
107.9
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
107.8
GTEX-QEL4-1226-SM-447A4
50-59 years, male
107.4
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
107.1
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
107.0
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
107.0
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
106.9
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
106.8
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
106.6
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
106.6
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
106.4
GTEX-14PJO-1726-SM-68719
60-69 years, male
105.9
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
105.5
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
105.2
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
104.8
GTEX-11ZUS-2526-SM-59872
30-39 years, male
103.2
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
103.0
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
102.7
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
102.5
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
102.4
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
102.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
101.8
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
101.1
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
101.0
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
100.9
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
100.2
GTEX-S33H-1626-SM-4AD68
30-39 years, male
99.4
GTEX-14JG1-1626-SM-664NH
40-49 years, male
99.3
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
98.6
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
98.3
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
98.2
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
98.2
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
98.1
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
98.1
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
97.1
GTEX-14XAO-0226-SM-68728
60-69 years, female
96.3
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
96.2
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
96.1
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
95.8
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
95.8
GTEX-QESD-2026-SM-447BI
20-29 years, male
95.4
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
95.2
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
95.2
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
95.1
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
94.9
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
94.7
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
94.5
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
94.2
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
94.0
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
93.9
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
93.7
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
93.3
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
93.2
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
93.0
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
92.9
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
92.8
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
92.7
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
92.4
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
92.4
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
92.1
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
92.1
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
91.4
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
91.0
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
91.0
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
91.0
GTEX-13112-1426-SM-5EGH8
50-59 years, male
90.9
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
90.7
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
90.6
GTEX-144GL-1426-SM-79OMA
50-59 years, male
90.3
GTEX-18A66-2026-SM-7189C
60-69 years, male
90.3
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
90.3
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
89.8
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
89.5
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
89.0
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
88.9
GTEX-17F96-1226-SM-79OK2
70-79 years, male
88.6
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
88.3
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
88.0
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
87.8
GTEX-RN64-1826-SM-48FDV
50-59 years, male
87.4
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
87.2
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
85.9
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
84.9
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
84.8
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
84.8
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
84.3
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
84.3
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
84.2
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
83.8
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
83.6
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
83.2
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
82.6
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
82.6
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
82.3
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
82.2
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
81.9
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
81.7
GTEX-R53T-0326-SM-48FEC
50-59 years, female
81.6
GTEX-X261-1726-SM-4PQYT
50-59 years, male
81.3
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
81.0
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
80.8
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
80.4
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
79.8
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
79.7
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
78.8
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
78.6
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
78.6
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
78.6
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
78.0
GTEX-1399T-0826-SM-5IFES
60-69 years, male
77.9
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
77.4
GTEX-18A7A-1526-SM-72D69
50-59 years, female
77.2
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
77.0
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
76.7
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
76.4
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
75.8
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
75.5
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
75.3
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
75.1
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
74.6
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
74.4
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
74.0
GTEX-Q734-0326-SM-48U15
40-49 years, female
73.6
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
73.5
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
73.4
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
73.4
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
73.2
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
72.9
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
72.7
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
72.4
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
71.7
GTEX-1B932-1426-SM-793AN
40-49 years, female
71.7
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
71.4
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
71.3
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
71.0
GTEX-14PHX-0526-SM-664NW
50-59 years, male
69.9
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
69.5
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
68.8
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
68.1
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
68.0
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
67.9
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
67.6
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
67.5
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
67.5
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
67.3
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
67.3
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
67.0
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
66.3
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
64.0
GTEX-11GSP-0626-SM-5986T
60-69 years, female
63.9
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
63.7
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
63.4
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
62.3
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
62.1
GTEX-1B933-1226-SM-731DW
50-59 years, female
61.5
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
58.2
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
58.2
GTEX-17HHE-0126-SM-79398
50-59 years, male
58.1
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
57.9
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
55.3
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
54.8
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
54.4
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
54.0
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
49.8
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
37.1
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
21.3
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
