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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:41.8 nTPM
HPA Brain:187.5 nTPM
GTEx:41.8 nTPM
FANTOM5:166.8 Scaled Tags Per Million
Pig:98.6 nTPM
Mouse:115.0 nTPM
Allen mouse:9.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

187.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 139.5
1830 Male, age 51, unknown 190.1
2411 Female, age 72, unknown 175.8
1833 Male, age 53, unknown 168.8
2019 Male, age 18, unknown 158.7
1870 Female, age 42, unknown 144.3
2586 Male, age 75, left hemisphere 127.1
2828 Female, age 72, unknown 125.8
2219 Male, age 76, both hemispheres 114.8
2666 Male, age 74, left hemisphere 99.7
1827 Male, age 72, unknown 90.1
Dorsal raphe nucleus
nTPM: 95.2
2750 Male, age 76, both hemispheres 200.7
2016 Female, age 72, unknown 99.0
1828 Male, age 53, unknown 82.5
2047 Male, age 72, unknown 47.4
2298 Female, age 72, unknown 46.6
Inferior colliculus
nTPM: 80.9
2849 Male, age 72, unknown 92.2
1848 Female, age 42, unknown 86.0
1890 Male, age 53, unknown 82.5
2097 Female, age 72, unknown 63.0
Median raphe nucleus
nTPM: 78.0
2220 Male, age 76, midline 78.0
Periaquaductal grey, anterior
nTPM: 68.2
2502 Female, age 75, unknown 72.9
1947 Male, age 18, unknown 71.9
1795 Male, age 51, unknown 59.9
Periaquaductal grey, dorsal
nTPM: 56.2
2464 Female, age 72, unknown 96.0
1831 Male, age 72, unknown 61.7
2850 Male, age 76, both hemispheres 35.2
1840 Male, age 53, unknown 31.8
Periaquaductal grey, lateral
nTPM: 69.5
2272 Male, age 74, both hemispheres 99.1
2053 Male, age 18, unknown 73.3
2140 Male, age 76, both hemispheres 36.0
Pretectal area
nTPM: 78.4
1815 Male, age 53, unknown 120.4
2316 Male, age 76, right hemisphere 116.8
2407 Male, age 75, both hemispheres 104.8
1817 Female, age 42, unknown 84.5
2825 Male, age 18, unknown 83.5
2007 Male, age 72, unknown 83.3
2273 Male, age 74, both hemispheres 77.0
2224 Female, age 72, unknown 62.8
2667 Female, age 75, unknown 45.0
1944 Female, age 72, unknown 43.3
1816 Male, age 51, unknown 41.0
Red nucleus
nTPM: 187.5
1904 Male, age 53, unknown 221.0
2823 Male, age 76, right hemisphere 217.6
2769 Male, age 72, unknown 208.9
2227 Male, age 72, unknown 208.8
1865 Male, age 51, unknown 207.7
1821 Female, age 72, unknown 200.3
2785 Male, age 18, unknown 191.9
2503 Female, age 72, unknown 181.1
2588 Male, age 74, left hemisphere 169.6
1954 Female, age 42, unknown 165.5
2725 Female, age 75, unknown 151.0
2584 Male, age 75, left hemisphere 127.0
Substantia nigra
nTPM: 92.2
2590 Female, age 75, unknown 142.0
2583 Male, age 75, right hemisphere 122.8
1851 Male, age 51, unknown 115.0
1889 Female, age 72, unknown 96.1
2409 Female, age 72, unknown 93.2
2699 Male, age 18, unknown 91.4
1941 Male, age 53, unknown 73.2
2241 Male, age 72, unknown 65.6
1916 Female, age 42, unknown 63.4
2665 Male, age 74, both hemispheres 59.2
Superior colliculus
nTPM: 109.8
1995 Male, age 72, unknown 178.5
1913 Female, age 42, unknown 169.0
1839 Male, age 51, unknown 120.5
1895 Male, age 76, right hemisphere 119.7
2668 Female, age 75, unknown 119.2
2587 Male, age 74, left hemisphere 114.0
1796 Male, age 53, unknown 85.2
2664 Male, age 75, both hemispheres 74.2
2261 Male, age 18, unknown 59.7
2087 Female, age 72, unknown 57.9
Ventral tegmental area
nTPM: 108.7
2223 Female, age 72, unknown 162.8
2410 Female, age 72, unknown 130.3
2021 Male, age 53, unknown 96.7
2218 Male, age 76, both hemispheres 89.1
1942 Male, age 51, unknown 89.0
1915 Female, age 42, unknown 84.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

41.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 41.8
Samples: 139

Max nTPM: 191.0
Min nTPM: 3.4
Std nTPM: 30.0
Median nTPM: 33.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 191.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 161.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 111.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 104.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 98.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 92.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 91.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 90.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 90.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 88.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 87.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 86.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 85.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 83.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 82.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 80.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 77.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 77.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 76.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 75.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 75.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 71.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 70.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 70.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 70.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 70.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 69.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 69.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 68.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 64.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 64.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 62.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 61.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 58.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 58.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 56.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 56.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 55.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 52.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 51.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 51.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 51.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 50.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 49.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 48.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 47.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 47.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 46.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 45.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 44.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 42.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 42.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 41.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 41.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 41.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 40.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 40.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 38.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 38.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 38.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 37.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 37.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 37.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 36.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 35.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 35.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 34.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 34.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 34.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 33.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 32.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 32.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 32.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 32.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 32.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 31.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 31.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 31.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 30.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 30.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 29.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 29.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 29.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 28.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 27.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 27.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 27.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 26.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 26.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 25.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 24.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 24.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 24.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 24.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 23.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 23.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 23.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 21.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 21.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 21.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 20.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 20.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 20.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 20.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 20.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 19.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 19.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 19.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 18.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 17.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 17.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 17.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 16.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 16.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 15.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 15.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 15.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 15.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 14.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 13.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 13.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 13.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 12.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 12.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 11.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 11.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 10.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 10.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 10.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 9.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 8.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 8.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 7.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 7.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 7.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 7.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 5.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 5.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 3.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

166.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 166.8
FF:10158-103A5 76 years, female 166.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

98.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 91.1
Samples: 4

Max nTPM: 146.7
Min nTPM: 55.2
Sample A Female 99.4
Sample B Female 55.2
Sample C Male 63.1
Sample D Male 146.7
Midbrain
nTPM: 98.6
Samples: 4

Max nTPM: 215.4
Min nTPM: 42.4
Sample A Female 215.4
Sample B Female 84.6
Sample C Male 42.4
Sample D Male 51.9
Periaqueductal gray
nTPM: 63.8
Samples: 3

Max nTPM: 75.7
Min nTPM: 48.2
Sample B Female 75.7
Sample C Male 48.2
Sample D Male 67.5
Superior colliculi
nTPM: 75.1
Samples: 4

Max nTPM: 95.6
Min nTPM: 37.2
Sample A Female 90.9
Sample B Female 37.2
Sample C Male 76.8
Sample D Male 95.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

115.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 115.0
Samples: 4

Max nTPM: 120.8
Min nTPM: 110.8
Sample A Male 112.3
Sample B Male 110.8
Sample C Female 120.8
Sample D Female 116.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.8
69447978 Antisense, RP_050419_02_D12, Mouse strain C57BL/6J (56 days, male) 9.8

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