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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:44.3 nTPM
HPA Brain:30.0 nTPM
GTEx:44.3 nTPM
FANTOM5:43.7 Scaled Tags Per Million
Pig:24.9 nTPM
Mouse:11.8 nTPM
Allen mouse:0.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

30.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 19.0
2828 Female, age 72, unknown 24.6
1870 Female, age 42, unknown 23.3
2666 Male, age 74, left hemisphere 22.4
2586 Male, age 75, left hemisphere 20.8
1827 Male, age 72, unknown 20.6
2019 Male, age 18, unknown 17.2
2411 Female, age 72, unknown 16.2
1830 Male, age 51, unknown 15.7
2219 Male, age 76, both hemispheres 14.5
1833 Male, age 53, unknown 14.4
Dorsal raphe nucleus
nTPM: 26.0
2016 Female, age 72, unknown 30.9
1828 Male, age 53, unknown 29.5
2298 Female, age 72, unknown 28.2
2047 Male, age 72, unknown 26.4
2750 Male, age 76, both hemispheres 15.1
Inferior colliculus
nTPM: 16.2
2097 Female, age 72, unknown 21.7
1848 Female, age 42, unknown 16.3
1890 Male, age 53, unknown 15.7
2849 Male, age 72, unknown 11.0
Median raphe nucleus
nTPM: 23.4
2220 Male, age 76, midline 23.4
Periaquaductal grey, anterior
nTPM: 26.3
1795 Male, age 51, unknown 29.8
2502 Female, age 75, unknown 27.8
1947 Male, age 18, unknown 21.5
Periaquaductal grey, dorsal
nTPM: 25.4
1840 Male, age 53, unknown 28.2
2850 Male, age 76, both hemispheres 28.0
1831 Male, age 72, unknown 24.3
2464 Female, age 72, unknown 21.0
Periaquaductal grey, lateral
nTPM: 30.0
2140 Male, age 76, both hemispheres 34.4
2053 Male, age 18, unknown 33.0
2272 Male, age 74, both hemispheres 22.5
Pretectal area
nTPM: 18.0
2273 Male, age 74, both hemispheres 27.3
2825 Male, age 18, unknown 26.4
2224 Female, age 72, unknown 25.6
2316 Male, age 76, right hemisphere 21.9
2407 Male, age 75, both hemispheres 18.3
1817 Female, age 42, unknown 15.0
1816 Male, age 51, unknown 14.7
1944 Female, age 72, unknown 12.5
2007 Male, age 72, unknown 12.1
1815 Male, age 53, unknown 12.0
2667 Female, age 75, unknown 12.0
Red nucleus
nTPM: 19.1
2503 Female, age 72, unknown 24.7
2725 Female, age 75, unknown 23.4
2227 Male, age 72, unknown 22.9
2823 Male, age 76, right hemisphere 20.6
1954 Female, age 42, unknown 19.9
2584 Male, age 75, left hemisphere 18.9
2769 Male, age 72, unknown 18.3
1865 Male, age 51, unknown 18.2
1821 Female, age 72, unknown 17.2
1904 Male, age 53, unknown 16.3
2588 Male, age 74, left hemisphere 15.8
2785 Male, age 18, unknown 13.3
Substantia nigra
nTPM: 18.4
2699 Male, age 18, unknown 29.5
2409 Female, age 72, unknown 22.0
2241 Male, age 72, unknown 20.6
1851 Male, age 51, unknown 19.1
2590 Female, age 75, unknown 17.7
2665 Male, age 74, both hemispheres 17.4
1916 Female, age 42, unknown 17.3
2583 Male, age 75, right hemisphere 14.8
1889 Female, age 72, unknown 12.8
1941 Male, age 53, unknown 12.5
Superior colliculus
nTPM: 19.3
1796 Male, age 53, unknown 26.0
1995 Male, age 72, unknown 24.7
2664 Male, age 75, both hemispheres 23.3
1913 Female, age 42, unknown 21.3
2668 Female, age 75, unknown 20.1
1839 Male, age 51, unknown 20.0
2587 Male, age 74, left hemisphere 17.8
2087 Female, age 72, unknown 16.4
2261 Male, age 18, unknown 12.0
1895 Male, age 76, right hemisphere 11.3
Ventral tegmental area
nTPM: 26.9
2021 Male, age 53, unknown 42.3
1942 Male, age 51, unknown 28.2
2223 Female, age 72, unknown 26.9
1915 Female, age 42, unknown 26.5
2410 Female, age 72, unknown 20.1
2218 Male, age 76, both hemispheres 17.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

44.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 44.3
Samples: 139

Max nTPM: 114.3
Min nTPM: 11.0
Std nTPM: 17.7
Median nTPM: 40.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 114.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 103.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 92.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 90.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 87.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 86.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 81.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 77.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 76.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 76.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 72.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 72.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 71.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 69.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 65.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 65.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 63.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 62.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 61.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 60.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 60.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 60.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 59.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 58.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 58.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 57.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 57.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 56.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 55.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 54.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 54.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 54.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 53.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 53.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 53.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 52.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 51.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 51.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 51.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 51.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 49.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 48.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 48.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 48.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 48.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 48.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 48.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 47.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 47.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 46.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 45.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 44.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 44.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 44.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 44.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 44.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 43.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 43.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 43.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 43.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 42.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 42.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 42.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 42.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 42.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 42.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 41.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 41.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 41.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 40.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 39.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 39.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 39.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 39.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 39.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 39.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 39.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 39.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 38.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 38.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 38.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 38.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 38.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 37.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 37.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 37.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 37.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 37.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 37.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 36.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 36.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 36.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 35.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 34.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 34.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 34.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 34.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 33.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 33.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 33.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 33.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 32.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 32.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 32.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 32.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 31.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 31.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 31.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 31.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 30.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 30.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 29.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 29.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 29.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 29.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 29.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 29.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 29.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 28.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 28.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 28.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 27.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 26.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 25.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 25.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 25.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 24.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 24.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 24.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 23.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 23.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 22.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 20.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 20.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 20.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 18.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 16.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 15.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 11.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

43.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 43.7
FF:10158-103A5 76 years, female 43.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

24.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 24.9
Samples: 4

Max nTPM: 32.7
Min nTPM: 14.5
Sample A Female 32.7
Sample B Female 28.7
Sample C Male 23.7
Sample D Male 14.5
Midbrain
nTPM: 18.0
Samples: 4

Max nTPM: 33.7
Min nTPM: 8.9
Sample A Female 33.7
Sample B Female 17.5
Sample C Male 11.7
Sample D Male 8.9
Periaqueductal gray
nTPM: 17.7
Samples: 3

Max nTPM: 22.4
Min nTPM: 14.7
Sample B Female 15.9
Sample C Male 22.4
Sample D Male 14.7
Superior colliculi
nTPM: 19.3
Samples: 4

Max nTPM: 30.3
Min nTPM: 11.1
Sample A Female 22.9
Sample B Female 30.3
Sample C Male 12.9
Sample D Male 11.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

11.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 11.9
Samples: 4

Max nTPM: 14.7
Min nTPM: 8.9
Sample A Male 14.7
Sample B Male 11.1
Sample C Female 8.9
Sample D Female 12.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.2
67978684 Antisense, RP_040923_01_E09, Mouse strain C57BL/6J (56 days, male) 0.2

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