Expression of RPS29 in urothelial cancer

BLADDER UROTHELIAL CARCINOMA (TCGA) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

RPS29 is not prognostic in Bladder Urothelial Carcinoma (TCGA)

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 456.98

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

5-year survival highⁱ N/A

5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average pTPM

2943.1

Number of samples

169

Samples

Sample	Description	pTPM
TCGA-BT-A0S7-01A	75 years, male, white, stage:Stage III, dead, 200 days	12143.0
TCGA-XF-AAMH-01A	80 years, male, white, stage:Stage IV, dead, 344 days	7717.6
TCGA-FJ-A3ZE-01A	65 years, male, white, stage:Stage IV, dead, 324 days	7522.4
TCGA-ZF-AA5N-01A	62 years, female, white, stage:Stage IV, dead, 168 days	7097.2
TCGA-G2-A2EL-01A	77 years, male, white, stage:Stage II, dead, 819 days	6902.0
TCGA-XF-AAML-01A	75 years, male, white, stage:Stage II, dead, 232 days	6858.5
TCGA-ZF-A9RD-01A	75 years, female, white, stage:Stage IV, dead, 408 days	6318.5
TCGA-XF-AAN8-01A	74 years, female, white, stage:Stage III, dead, 118 days	6283.2
TCGA-FJ-A871-01A	49 years, male, white, stage:Stage III, dead, 272 days	6263.0
TCGA-GU-AATO-01A	75 years, male, white, stage:Stage IV, dead, 324 days	6027.6
TCGA-K4-A5RI-01A	67 years, female, white, stage:Stage III, dead, 356 days	6026.0
TCGA-FD-A62O-01A	74 years, male, white, stage:Stage IV, dead, 216 days	5950.4
TCGA-G2-A2EO-01A	69 years, male, white, stage:Stage III, dead, 1804 days	5841.6
TCGA-GU-A762-01A	87 years, male, white, stage:Stage IV, dead, 232 days	5839.3
TCGA-FD-A43Y-01A	65 years, male, white, stage:Stage III, dead, 474 days	5674.9
TCGA-GC-A3BM-01A	70 years, male, white, stage:Stage II, dead, 651 days	5655.3
TCGA-C4-A0F7-01A	77 years, male, stage:Stage IV, dead, 62 days	5645.6
TCGA-FD-A6TD-01A	77 years, male, white, stage:Stage III, dead, 386 days	5594.7
TCGA-UY-A78M-01A	81 years, female, asian, stage:Stage IV, dead, 690 days	5448.9
TCGA-BT-A20N-01A	72 years, male, stage:Stage III, dead, 795 days	5421.2
TCGA-G2-A2ES-01A	85 years, male, white, stage:Stage II, dead, 1004 days	5172.7
TCGA-FD-A3B3-01A	74 years, female, white, stage:Stage III, dead, 974 days	5108.3
TCGA-G2-A2EC-01A	58 years, female, black or african american, stage:Stage II, dead, 696 days	5084.6
TCGA-DK-AA75-01A	82 years, male, white, stage:Stage III, dead, 340 days	5082.5
TCGA-GU-AATQ-01A	68 years, male, white, stage:Stage III, dead, 213 days	5074.8
TCGA-C4-A0EZ-01A	69 years, female, stage:Stage IV, dead, 273 days	5034.9
TCGA-XF-AAN1-01A	75 years, female, stage:Stage III, dead, 941 days	5001.4
TCGA-DK-AA6W-01A	78 years, male, white, stage:Stage II, dead, 415 days	4986.1
TCGA-GU-A42Q-01A	67 years, male, white, stage:Stage III, dead, 344 days	4813.3
TCGA-E7-A3X6-01A	70 years, male, white, stage:Stage II, dead, 904 days	4736.5
TCGA-BT-A20X-01A	56 years, male, white, stage:Stage IV, dead, 251 days	4643.7
TCGA-4Z-AA7R-01A	73 years, male, black or african american, stage:Stage IV, dead, 522 days	4608.8
TCGA-XF-A8HF-01A	80 years, male, white, stage:Stage III, dead, 2954 days	4480.2
TCGA-4Z-AA7N-01A	65 years, male, white, stage:Stage III, dead, 1367 days	4476.9
TCGA-XF-AAMT-01A	75 years, female, white, stage:Stage IV, dead, 90 days	4469.6
TCGA-ZF-AA54-01A	71 years, male, white, stage:Stage III, dead, 590 days	4443.2
TCGA-K4-A4AC-01A	83 years, male, white, stage:Stage II, dead, 278 days	4409.1
TCGA-XF-A8HG-01A	69 years, male, white, stage:Stage III, dead, 467 days	4385.2
TCGA-XF-AAN7-01A	60 years, male, white, stage:Stage IV, dead, 565 days	4326.8
TCGA-ZF-AA4U-01A	70 years, male, white, stage:Stage III, dead, 262 days	4318.4
TCGA-UY-A78N-01A	80 years, male, white, stage:Stage IV, dead, 2641 days	4316.8
TCGA-FD-A5BX-01A	82 years, male, white, stage:Stage IV, dead, 173 days	4290.7
TCGA-ZF-A9RN-01A	67 years, female, white, stage:Stage III, dead, 615 days	4250.4
TCGA-XF-AAN2-01A	73 years, male, white, stage:Stage II, dead, 1869 days	4190.4
TCGA-FD-A3B5-01A	86 years, male, black or african american, stage:Stage IV, dead, 272 days	4180.7
TCGA-HQ-A5ND-01A	78 years, male, stage:Stage IV, dead, 274 days	4163.0
TCGA-ZF-AA4N-01A	74 years, male, white, stage:Stage II, dead, 88 days	4093.5
TCGA-E7-A97P-01A	73 years, male, asian, stage:Stage II, dead, 437 days	3956.3
TCGA-CU-A72E-01A	76 years, male, white, stage:Stage IV, dead, 413 days	3861.2
TCGA-DK-AA6Q-01A	61 years, female, white, stage:Stage IV, dead, 413 days	3854.1
TCGA-UY-A78K-01A	60 years, male, white, stage:Stage IV, dead, 536 days	3840.5
TCGA-GV-A3QH-01A	67 years, male, white, stage:Stage II, dead, 258 days	3807.2
TCGA-CF-A47T-01A	58 years, female, asian, stage:Stage II, dead, 385 days	3784.4
TCGA-XF-A9SH-01A	65 years, female, asian, stage:Stage II, dead, 1971 days	3780.1
TCGA-DK-A2I2-01A	63 years, female, white, stage:Stage IV, dead, 237 days	3756.8
TCGA-4Z-AA86-01A	66 years, male, black or african american, stage:Stage IV, dead, 311 days	3753.5
TCGA-2F-A9KP-01A	66 years, male, white, stage:Stage IV, dead, 364 days	3739.7
TCGA-BT-A20W-01A	71 years, male, white, stage:Stage II, dead, 254 days	3733.7
TCGA-FJ-A3Z9-01A	72 years, male, white, stage:'--, dead, 385 days	3728.8
TCGA-DK-A1AB-01A	74 years, female, white, stage:Stage IV, dead, 508 days	3653.3
TCGA-XF-A9SP-01A	59 years, male, white, stage:Stage III, dead, 454 days	3647.9
TCGA-XF-A8HI-01A	57 years, female, white, stage:Stage IV, dead, 544 days	3630.8
TCGA-DK-A3IU-01A	58 years, male, white, stage:Stage II, dead, 706 days	3607.4
TCGA-CU-A0YO-01A	84 years, male, white, stage:Stage IV, dead, 149 days	3589.8
TCGA-FD-A3B4-01A	55 years, female, black or african american, stage:Stage III, dead, 510 days	3544.4
TCGA-XF-AAMW-01A	79 years, female, white, stage:Stage IV, dead, 253 days	3544.0
TCGA-FD-A6TG-01A	73 years, male, white, stage:Stage IV, dead, 93 days	3530.0
TCGA-ZF-A9R3-01A	53 years, female, white, stage:Stage II, dead, 949 days	3504.5
TCGA-ZF-A9R0-01A	82 years, male, white, stage:Stage III, dead, 680 days	3476.8
TCGA-GV-A3JV-01A	66 years, male, white, stage:Stage IV, dead, 434 days	3476.8
TCGA-5N-A9KM-01A	73 years, female, white, stage:Stage III, dead, 530 days	3467.6
TCGA-FD-A3B7-01A	66 years, male, black or african american, stage:Stage III, dead, 122 days	3462.9
TCGA-ZF-AA56-01A	79 years, female, white, stage:Stage III, dead, 259 days	3426.3
TCGA-FD-A62P-01A	76 years, male, white, stage:Stage II, dead, 191 days	3417.6
TCGA-BT-A20V-01A	59 years, female, black or african american, stage:Stage IV, dead, 154 days	3410.7
TCGA-BL-A13J-01A	65 years, male, white, stage:Stage IV, dead, 81 days	3404.0
TCGA-CU-A0YN-01A	60 years, male, white, stage:Stage III, dead, 393 days	3398.4
TCGA-BT-A3PH-01A	76 years, male, white, stage:Stage IV, dead, 142 days	3345.4
TCGA-FD-A6TF-01A	80 years, female, white, stage:Stage IV, dead, 69 days	3342.2
TCGA-BT-A2LB-01A	73 years, female, white, stage:Stage III, dead, 492 days	3316.8
TCGA-G2-A3IB-01A	66 years, male, black or african american, stage:Stage II, dead, 220 days	3301.7
TCGA-BL-A3JM-01A	62 years, male, white, stage:Stage III, dead, 205 days	3277.3
TCGA-4Z-AA7Q-01A	79 years, male, white, stage:Stage III, dead, 510 days	3206.5
TCGA-XF-A8HC-01A	79 years, male, asian, stage:Stage IV, dead, 200 days	3206.0
TCGA-BT-A20Q-01A	73 years, male, white, stage:Stage IV, dead, 593 days	3199.6
TCGA-2F-A9KO-01A	63 years, male, white, stage:Stage IV, dead, 734 days	3183.9
TCGA-FD-A3N5-01A	69 years, male, black or african american, stage:Stage II, dead, 685 days	3130.0
TCGA-GU-A42R-01A	68 years, male, white, stage:Stage IV, dead, 577 days	3130.0
TCGA-BT-A20J-01A	75 years, male, white, stage:Stage II, dead, 579 days	3093.8
TCGA-FD-A3B6-01A	75 years, male, white, stage:Stage II, dead, 1005 days	3074.0
TCGA-E5-A4TZ-01A	64 years, male, white, stage:Stage IV, dead, 467 days	2970.6
TCGA-FD-A5C0-01A	61 years, male, white, stage:Stage IV, dead, 550 days	2948.9
TCGA-HQ-A5NE-01A	57 years, male, stage:Stage III, dead, 370 days	2938.4
TCGA-CU-A0YR-01A	83 years, male, white, stage:Stage IV, dead, 460 days	2864.0
TCGA-BT-A0YX-01A	70 years, female, white, stage:Stage III, dead, 400 days	2861.9
TCGA-5N-A9KI-01A	76 years, female, white, stage:Stage III, dead, 76 days	2825.1
TCGA-BT-A3PK-01A	80 years, male, white, stage:Stage II, dead, 303 days	2793.6
TCGA-DK-A3IQ-01A	74 years, male, white, stage:Stage III, dead, 539 days	2774.5
TCGA-DK-A1A5-01A	79 years, male, white, stage:Stage II, dead, 65 days	2757.9
TCGA-E7-A4XJ-01A	66 years, male, asian, stage:Stage II, dead, 68 days	2739.6
TCGA-XF-A9SK-01A	65 years, male, white, stage:Stage IV, dead, 486 days	2735.7
TCGA-FD-A3SJ-01A	59 years, male, white, stage:Stage IV, dead, 739 days	2727.6
TCGA-DK-A1A3-01A	60 years, male, white, stage:Stage IV, dead, 665 days	2637.2
TCGA-CU-A5W6-01A	70 years, male, white, stage:Stage III, dead, 56 days	2613.9
TCGA-XF-A9SZ-01A	79 years, male, white, stage:Stage IV, dead, 859 days	2612.1
TCGA-FD-A6TH-01A	63 years, male, white, stage:Stage IV, dead, 131 days	2550.4
TCGA-FD-A3SS-01A	66 years, male, white, stage:Stage IV, dead, 391 days	2541.2
TCGA-FD-A3SQ-01A	62 years, male, white, stage:Stage IV, dead, 1423 days	2491.6
TCGA-XF-AAN0-01A	68 years, male, white, stage:Stage IV, dead, 1718 days	2434.6
TCGA-2F-A9KW-01A	67 years, female, white, stage:Stage III, dead, 254 days	2365.1
TCGA-FD-A6TI-01A	73 years, male, white, stage:Stage IV, dead, 294 days	2358.2
TCGA-BT-A2LD-01A	78 years, female, white, stage:Stage IV, dead, 623 days	2354.7
TCGA-4Z-AA82-01A	59 years, male, black or african american, stage:Stage IV, dead, 1556 days	2281.3
TCGA-FD-A3SM-01A	70 years, male, white, stage:Stage IV, dead, 547 days	2258.6
TCGA-FD-A5BV-01A	47 years, female, white, stage:Stage III, dead, 163 days	2210.2
TCGA-DK-A3IK-01A	87 years, male, white, stage:Stage IV, dead, 146 days	2198.5
TCGA-XF-A8HH-01A	61 years, female, white, stage:Stage IV, dead, 57 days	2158.8
TCGA-CF-A9FL-01A	85 years, male, asian, stage:Stage III, dead, 565 days	2143.8
TCGA-GV-A3QF-01A	79 years, male, white, stage:Stage IV, dead, 617 days	1701.5
TCGA-XF-A9ST-01A	68 years, male, white, stage:Stage III, dead, 128 days	1166.2
TCGA-BL-A13I-01A	57 years, female, white, stage:Stage III, dead, 223 days	937.4
TCGA-FD-A5BT-01A	84 years, male, white, stage:Stage III, dead, 328 days	853.4
TCGA-DK-A3X2-01A	85 years, male, white, stage:Stage IV, dead, 547 days	790.3
TCGA-GU-A767-01A	81 years, male, white, stage:Stage IV, dead, 144 days	717.6
TCGA-FD-A3SO-01A	68 years, male, white, stage:Stage IV, dead, 168 days	640.6
TCGA-XF-AAN4-01A	77 years, female, white, stage:Stage III, dead, 823 days	626.5
TCGA-DK-A3IL-01A	79 years, female, white, stage:Stage IV, dead, 413 days	576.5
TCGA-DK-A3IN-01A	72 years, male, white, stage:Stage III, dead, 250 days	530.1
TCGA-GU-A42P-01A	72 years, male, white, stage:Stage IV, dead, 332 days	509.2
TCGA-S5-A6DX-01A	83 years, male, white, stage:Stage IV, dead, 56 days	485.3
TCGA-G2-AA3C-01A	66 years, male, white, stage:Stage IV, dead, 211 days	457.0
TCGA-GC-A3I6-01A	45 years, male, white, stage:Stage III, dead, 630 days	441.6
TCGA-G2-A3IE-01A	51 years, male, white, stage:Stage II, dead, 612 days	404.9
TCGA-XF-AAME-01A	64 years, female, white, stage:Stage II, dead, 2828 days	392.2
TCGA-XF-A9T8-01A	64 years, male, white, stage:Stage III, dead, 418 days	389.2
TCGA-YC-A9TC-01A	71 years, male, white, stage:Stage IV, dead, 20 days	387.1
TCGA-GV-A40E-01A	75 years, male, white, stage:Stage II, dead, 261 days	386.3
TCGA-XF-A9T2-01A	54 years, male, white, stage:Stage III, dead, 575 days	383.2
TCGA-FD-A3SL-01A	60 years, male, white, stage:Stage IV, dead, 712 days	381.7
TCGA-XF-A9SX-01A	63 years, female, white, stage:Stage IV, dead, 719 days	357.0
TCGA-ZF-A9RE-01A	78 years, female, white, stage:Stage II, dead, 106 days	352.5
TCGA-XF-A9SL-01A	69 years, male, white, stage:Stage IV, dead, 2020 days	329.8
TCGA-FD-A3SR-01A	68 years, male, white, stage:Stage IV, dead, 602 days	318.8
TCGA-XF-A9SV-01A	82 years, male, white, stage:Stage IV, dead, 388 days	312.0
TCGA-E7-A541-01A	66 years, male, white, stage:Stage II, dead, 778 days	310.4
TCGA-4Z-AA80-01A	73 years, male, white, stage:Stage II, dead, 19 days	304.3
TCGA-BT-A20U-01A	70 years, female, white, stage:Stage III, dead, 455 days	299.2
TCGA-FD-A5BZ-01A	77 years, female, white, stage:Stage IV, dead, 835 days	291.4
TCGA-FD-A62S-01A	60 years, female, black or african american, stage:Stage III, dead, 406 days	280.3
TCGA-DK-AA6L-01A	48 years, male, white, stage:Stage IV, dead, 1163 days	269.7
TCGA-4Z-AA81-01A	80 years, male, white, stage:Stage II, dead, 1270 days	268.7
TCGA-XF-AAMZ-01A	81 years, female, white, stage:Stage IV, dead, 1348 days	251.5
TCGA-XF-A9SJ-01A	83 years, male, white, stage:Stage IV, dead, 98 days	249.7
TCGA-BT-A20O-01A	75 years, male, white, stage:Stage III, dead, 370 days	246.7
TCGA-4Z-AA7S-01A	66 years, male, black or african american, stage:Stage III, dead, 1064 days	241.2
TCGA-DK-A3IM-01A	76 years, male, white, stage:Stage III, dead, 248 days	235.1
TCGA-XF-A9SU-01A	74 years, female, white, stage:Stage IV, dead, 182 days	222.2
TCGA-DK-A2HX-01A	80 years, female, white, stage:Stage IV, dead, 1420 days	219.1
TCGA-XF-A9SW-01A	85 years, male, white, stage:Stage IV, dead, 362 days	212.1
TCGA-ZF-AA4T-01A	65 years, male, white, stage:Stage IV, dead, 599 days	205.1
TCGA-BT-A20T-01A	63 years, male, white, stage:Stage IV, dead, 453 days	202.0
TCGA-ZF-AA52-01A	70 years, male, white, stage:Stage III, dead, 1077 days	197.2
TCGA-SY-A9G0-01A	82 years, male, white, stage:Stage IV, dead, 1008 days	170.3
TCGA-ZF-A9R9-01A	58 years, male, white, stage:Stage IV, dead, 864 days	166.4
TCGA-XF-AAMJ-01A	70 years, male, asian, stage:Stage III, dead, 1670 days	142.9
TCGA-ZF-AA4R-01A	67 years, male, white, stage:Stage IV, dead, 1036 days	140.9
TCGA-XF-AAMX-01A	87 years, female, black or african american, stage:Stage III, dead, 206 days	138.6
TCGA-2F-A9KR-01A	59 years, female, stage:Stage III, dead, 3183 days	93.0
TCGA-BT-A20P-01A	81 years, female, white, stage:Stage III, dead, 544 days	84.2
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UROTHELIAL CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.	Antibody HPA004107
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Urothelial carcinoma, High grade
Urothelial carcinoma, Low grade