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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:254.1 nTPM
HPA Brain:144.6 nTPM
GTEx:254.1 nTPM
FANTOM5:110.1 Scaled Tags Per Million
Pig:4.9 nTPM
Mouse:540.8 nTPM
Allen mouse:14.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

144.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 110.5
2019 Male, age 18, unknown 140.8
2411 Female, age 72, unknown 134.5
1827 Male, age 72, unknown 124.4
1870 Female, age 42, unknown 109.3
1833 Male, age 53, unknown 107.5
2219 Male, age 76, both hemispheres 106.4
1830 Male, age 51, unknown 101.1
2666 Male, age 74, left hemisphere 98.3
2828 Female, age 72, unknown 96.4
2586 Male, age 75, left hemisphere 86.5
Dorsal raphe nucleus
nTPM: 128.2
2298 Female, age 72, unknown 157.4
1828 Male, age 53, unknown 142.5
2047 Male, age 72, unknown 132.1
2016 Female, age 72, unknown 105.5
2750 Male, age 76, both hemispheres 103.9
Inferior colliculus
nTPM: 120.2
2097 Female, age 72, unknown 139.2
1890 Male, age 53, unknown 126.5
1848 Female, age 42, unknown 117.0
2849 Male, age 72, unknown 98.3
Median raphe nucleus
nTPM: 96.9
2220 Male, age 76, midline 96.9
Periaquaductal grey, anterior
nTPM: 113.1
1947 Male, age 18, unknown 120.5
2502 Female, age 75, unknown 113.2
1795 Male, age 51, unknown 105.5
Periaquaductal grey, dorsal
nTPM: 96.5
1840 Male, age 53, unknown 101.3
2464 Female, age 72, unknown 97.8
1831 Male, age 72, unknown 94.7
2850 Male, age 76, both hemispheres 92.2
Periaquaductal grey, lateral
nTPM: 97.2
2272 Male, age 74, both hemispheres 111.1
2053 Male, age 18, unknown 98.3
2140 Male, age 76, both hemispheres 82.0
Pretectal area
nTPM: 123.0
1817 Female, age 42, unknown 154.0
2007 Male, age 72, unknown 149.7
1816 Male, age 51, unknown 145.1
1944 Female, age 72, unknown 140.7
1815 Male, age 53, unknown 125.5
2667 Female, age 75, unknown 121.5
2273 Male, age 74, both hemispheres 120.1
2224 Female, age 72, unknown 110.5
2316 Male, age 76, right hemisphere 99.0
2825 Male, age 18, unknown 98.3
2407 Male, age 75, both hemispheres 88.9
Red nucleus
nTPM: 117.7
1821 Female, age 72, unknown 178.5
2503 Female, age 72, unknown 126.0
2725 Female, age 75, unknown 120.0
2823 Male, age 76, right hemisphere 119.5
2785 Male, age 18, unknown 117.6
1865 Male, age 51, unknown 116.5
1954 Female, age 42, unknown 109.5
2588 Male, age 74, left hemisphere 108.9
2769 Male, age 72, unknown 108.6
2227 Male, age 72, unknown 107.7
1904 Male, age 53, unknown 103.7
2584 Male, age 75, left hemisphere 95.7
Substantia nigra
nTPM: 144.6
1916 Female, age 42, unknown 184.4
2241 Male, age 72, unknown 174.1
1851 Male, age 51, unknown 160.5
1941 Male, age 53, unknown 154.2
1889 Female, age 72, unknown 153.1
2409 Female, age 72, unknown 152.1
2665 Male, age 74, both hemispheres 137.1
2590 Female, age 75, unknown 121.0
2699 Male, age 18, unknown 118.2
2583 Male, age 75, right hemisphere 90.9
Superior colliculus
nTPM: 110.5
1895 Male, age 76, right hemisphere 135.4
2587 Male, age 74, left hemisphere 132.2
2668 Female, age 75, unknown 123.3
2087 Female, age 72, unknown 120.9
2261 Male, age 18, unknown 113.9
1796 Male, age 53, unknown 110.8
1839 Male, age 51, unknown 104.8
1913 Female, age 42, unknown 93.0
1995 Male, age 72, unknown 86.5
2664 Male, age 75, both hemispheres 84.1
Ventral tegmental area
nTPM: 120.0
2410 Female, age 72, unknown 148.6
1915 Female, age 42, unknown 143.2
2218 Male, age 76, both hemispheres 121.1
2223 Female, age 72, unknown 108.0
1942 Male, age 51, unknown 105.0
2021 Male, age 53, unknown 94.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

254.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 254.1
Samples: 139

Max nTPM: 518.2
Min nTPM: 106.1
Std nTPM: 67.2
Median nTPM: 245.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 518.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 467.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 439.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 421.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 397.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 389.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 387.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 384.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 376.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 374.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 373.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 352.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 352.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 349.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 344.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 341.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 337.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 335.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 329.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 324.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 323.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 321.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 319.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 318.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 301.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 300.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 299.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 298.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 294.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 293.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 291.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 288.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 280.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 279.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 278.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 278.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 278.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 277.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 277.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 275.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 274.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 273.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 273.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 273.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 272.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 272.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 271.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 270.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 270.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 269.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 269.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 267.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 265.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 264.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 262.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 260.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 255.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 254.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 252.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 251.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 251.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 250.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 249.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 249.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 249.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 248.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 247.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 246.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 246.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 245.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 245.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 243.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 242.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 241.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 241.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 238.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 237.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 237.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 234.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 233.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 232.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 230.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 230.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 229.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 224.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 223.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 219.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 219.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 217.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 216.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 216.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 215.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 215.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 214.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 214.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 213.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 213.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 212.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 209.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 207.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 207.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 206.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 206.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 205.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 204.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 204.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 202.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 200.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 200.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 199.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 199.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 198.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 196.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 194.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 194.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 194.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 193.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 192.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 190.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 189.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 187.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 186.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 186.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 185.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 184.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 184.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 184.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 184.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 183.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 178.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 178.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 175.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 173.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 172.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 169.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 165.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 156.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 137.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 106.1
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

110.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 110.1
FF:10158-103A5 76 years, female 110.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

4.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 3.2
Samples: 4

Max nTPM: 7.0
Min nTPM: 0.9
Sample A Female 0.9
Sample B Female 3.0
Sample C Male 2.0
Sample D Male 7.0
Midbrain
nTPM: 2.8
Samples: 4

Max nTPM: 4.2
Min nTPM: 1.8
Sample A Female 1.8
Sample B Female 4.2
Sample C Male 1.9
Sample D Male 3.3
Periaqueductal gray
nTPM: 4.9
Samples: 3

Max nTPM: 6.1
Min nTPM: 3.7
Sample B Female 4.8
Sample C Male 3.7
Sample D Male 6.1
Superior colliculi
nTPM: 3.2
Samples: 4

Max nTPM: 6.0
Min nTPM: 1.1
Sample A Female 1.1
Sample B Female 6.0
Sample C Male 1.8
Sample D Male 3.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

540.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 540.8
Samples: 4

Max nTPM: 573.1
Min nTPM: 523.6
Sample A Male 573.1
Sample B Male 528.0
Sample C Female 523.6
Sample D Female 538.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

14.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 14.9
576416 Antisense, RP_040826_01_G02, Mouse strain C57BL/6J (56 days, male) 16.5
1159 Antisense, RP_Baylor_253881, Mouse strain C57BL/6J (56 days, male) 13.3
1158 Antisense, RP_Baylor_253881, Mouse strain C57BL/6J (56 days, male) 10.4

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


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