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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:13.6 nTPM
HPA Brain:135.3 nTPM
GTEx:13.6 nTPM
FANTOM5:83.8 Scaled Tags Per Million
Pig:37.2 nTPM
Mouse:21.0 nTPM
Allen mouse:6.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

135.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 135.3
2219 Male, age 76, both hemispheres 214.4
1833 Male, age 53, unknown 149.4
1830 Male, age 51, unknown 148.9
2586 Male, age 75, left hemisphere 136.0
2666 Male, age 74, left hemisphere 128.9
2019 Male, age 18, unknown 127.0
1827 Male, age 72, unknown 115.5
2828 Female, age 72, unknown 114.9
1870 Female, age 42, unknown 109.7
2411 Female, age 72, unknown 107.9
Dorsal raphe nucleus
nTPM: 109.8
2750 Male, age 76, both hemispheres 135.0
1828 Male, age 53, unknown 111.6
2047 Male, age 72, unknown 107.3
2016 Female, age 72, unknown 106.7
2298 Female, age 72, unknown 88.2
Inferior colliculus
nTPM: 107.4
2849 Male, age 72, unknown 136.1
1890 Male, age 53, unknown 108.0
1848 Female, age 42, unknown 103.4
2097 Female, age 72, unknown 82.0
Median raphe nucleus
nTPM: 116.2
2220 Male, age 76, midline 116.2
Periaquaductal grey, anterior
nTPM: 123.7
1947 Male, age 18, unknown 144.6
2502 Female, age 75, unknown 113.5
1795 Male, age 51, unknown 113.0
Periaquaductal grey, dorsal
nTPM: 106.5
2850 Male, age 76, both hemispheres 111.7
2464 Female, age 72, unknown 110.2
1831 Male, age 72, unknown 102.9
1840 Male, age 53, unknown 101.3
Periaquaductal grey, lateral
nTPM: 124.2
2272 Male, age 74, both hemispheres 133.2
2140 Male, age 76, both hemispheres 123.3
2053 Male, age 18, unknown 116.2
Pretectal area
nTPM: 118.5
2407 Male, age 75, both hemispheres 160.6
2667 Female, age 75, unknown 143.5
2316 Male, age 76, right hemisphere 139.8
2825 Male, age 18, unknown 129.4
2273 Male, age 74, both hemispheres 120.5
2224 Female, age 72, unknown 113.4
1815 Male, age 53, unknown 109.2
2007 Male, age 72, unknown 108.2
1817 Female, age 42, unknown 96.3
1816 Male, age 51, unknown 92.2
1944 Female, age 72, unknown 90.1
Red nucleus
nTPM: 133.9
2823 Male, age 76, right hemisphere 171.7
2588 Male, age 74, left hemisphere 163.1
1865 Male, age 51, unknown 143.4
2584 Male, age 75, left hemisphere 142.3
2227 Male, age 72, unknown 132.1
1904 Male, age 53, unknown 132.0
2769 Male, age 72, unknown 129.4
2785 Male, age 18, unknown 129.0
2503 Female, age 72, unknown 126.0
2725 Female, age 75, unknown 122.9
1821 Female, age 72, unknown 108.6
1954 Female, age 42, unknown 105.8
Substantia nigra
nTPM: 110.5
2583 Male, age 75, right hemisphere 125.6
1941 Male, age 53, unknown 122.6
2699 Male, age 18, unknown 119.6
2241 Male, age 72, unknown 113.0
2409 Female, age 72, unknown 109.3
1851 Male, age 51, unknown 108.6
2590 Female, age 75, unknown 106.0
1889 Female, age 72, unknown 105.3
2665 Male, age 74, both hemispheres 100.5
1916 Female, age 42, unknown 94.9
Superior colliculus
nTPM: 123.0
1895 Male, age 76, right hemisphere 148.6
2664 Male, age 75, both hemispheres 142.2
1913 Female, age 42, unknown 140.9
1839 Male, age 51, unknown 131.0
2587 Male, age 74, left hemisphere 127.2
1995 Male, age 72, unknown 122.7
2668 Female, age 75, unknown 120.0
1796 Male, age 53, unknown 107.1
2261 Male, age 18, unknown 98.2
2087 Female, age 72, unknown 92.0
Ventral tegmental area
nTPM: 116.1
2223 Female, age 72, unknown 128.6
2218 Male, age 76, both hemispheres 126.6
1942 Male, age 51, unknown 123.0
2021 Male, age 53, unknown 112.4
2410 Female, age 72, unknown 104.4
1915 Female, age 42, unknown 101.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

13.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 13.6
Samples: 139

Max nTPM: 45.4
Min nTPM: 4.1
Std nTPM: 5.5
Median nTPM: 12.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 45.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 29.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 27.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 26.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 25.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 24.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 24.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 22.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 22.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 21.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 21.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 21.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 21.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 20.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 20.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 19.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 19.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 18.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 18.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 18.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 17.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 17.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 17.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 17.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 16.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 16.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 16.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 16.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 16.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 16.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 16.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 16.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 15.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 15.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 15.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 15.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 15.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 15.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 15.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 15.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 15.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 15.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 15.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 15.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 15.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 14.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 14.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 14.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 14.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 14.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 14.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 13.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 13.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 13.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 13.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 13.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 13.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 13.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 13.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 13.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 13.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 13.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 13.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 13.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 13.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 13.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 13.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 13.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 13.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 12.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 12.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 12.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 12.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 12.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 12.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 12.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 12.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 12.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 12.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 12.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 12.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 12.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 12.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 12.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 12.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 12.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 12.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 12.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 12.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 11.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 11.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 11.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 11.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 11.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 11.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 11.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 10.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 10.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 10.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 10.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 10.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 10.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 10.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 9.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 9.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 9.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 9.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 9.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 9.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 9.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 9.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 9.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 9.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 9.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 9.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 8.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 8.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 8.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 8.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 8.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 8.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 8.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 8.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 7.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 7.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 7.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 7.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 7.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 7.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 7.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 6.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 6.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 6.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 6.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 6.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 5.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 5.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 4.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 4.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

83.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 83.8
FF:10158-103A5 76 years, female 83.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

37.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 36.5
Samples: 4

Max nTPM: 51.1
Min nTPM: 28.5
Sample A Female 32.7
Sample B Female 28.5
Sample C Male 33.6
Sample D Male 51.1
Midbrain
nTPM: 37.2
Samples: 4

Max nTPM: 52.8
Min nTPM: 31.5
Sample A Female 52.8
Sample B Female 32.4
Sample C Male 31.5
Sample D Male 32.1
Periaqueductal gray
nTPM: 28.2
Samples: 3

Max nTPM: 30.9
Min nTPM: 25.1
Sample B Female 30.9
Sample C Male 25.1
Sample D Male 28.7
Superior colliculi
nTPM: 34.0
Samples: 4

Max nTPM: 40.6
Min nTPM: 24.3
Sample A Female 31.8
Sample B Female 24.3
Sample C Male 39.3
Sample D Male 40.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

21.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 21.0
Samples: 4

Max nTPM: 23.5
Min nTPM: 17.7
Sample A Male 17.7
Sample B Male 20.0
Sample C Female 23.5
Sample D Female 22.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

6.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.0
71281123 Antisense, RP_050818_02_B08, Mouse strain C57BL/6J (56 days, male) 7.7
71574522 Antisense, RP_050915_03_H04, Mouse strain C57BL/6J (56 days, male) 4.3

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