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DBNDD2
HPA
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  • DBNDD2
PROTEIN SUMMARY GENE INFORMATION RNA DATA ANTIBODY DATA
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

DBNDD2
Synonyms C20orf35, HSMNP1
Gene descriptioni

Full gene name according to HGNC.

Dysbindin domain containing 2
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Chromosome 20
Cytoband q13.12
Chromosome location (bp) 45406057 - 45410610
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

9
Ensembl ENSG00000244274 (version 109)
Entrez gene 55861
HGNC HGNC:15881
UniProt Q9BQY9 (UniProt - Evidence at protein level)
neXtProt NX_Q9BQY9
GeneCards DBNDD2
Antibodypedia DBNDD2 antibodies


PROTEIN FUNCTION
Protein function (UniProt)i

Useful information about the protein provided by UniProt.

May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro).... show less
Gene summary (Entrez)i

Useful information about the gene from Entrez

Involved in negative regulation of protein kinase activity. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]... show less
PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
(predicted)
Transmembrane regions
(predicted)
DBNDD2-201
ENSP00000349822
ENST00000357275
Q9BQY9
[Direct mapping] Dysbindin domain-containing protein 2
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006469 [negative regulation of protein kinase activity]
Show all
161 aa
17.5 kDa
No 0
DBNDD2-202
ENSP00000354250
ENST00000360981
Q9BQY9
[Direct mapping] Dysbindin domain-containing protein 2
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006469 [negative regulation of protein kinase activity]
Show all
161 aa
17.5 kDa
No 0
DBNDD2-203
ENSP00000361795
ENST00000372710
Q9BQY9
[Direct mapping] Dysbindin domain-containing protein 2
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006469 [negative regulation of protein kinase activity]
Show all
161 aa
17.5 kDa
No 0
DBNDD2-204
ENSP00000361797
ENST00000372712
Q9BQY9
[Direct mapping] Dysbindin domain-containing protein 2
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006469 [negative regulation of protein kinase activity]
Show all
161 aa
17.5 kDa
No 0
DBNDD2-205
ENSP00000361802
ENST00000372717
Q9BQY9
[Direct mapping] Dysbindin domain-containing protein 2
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006469 [negative regulation of protein kinase activity]
Show all
112 aa
12.6 kDa
No 0
DBNDD2-206
ENSP00000361805
ENST00000372720
Q9BQY9
[Direct mapping] Dysbindin domain-containing protein 2
Show all
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006469 [negative regulation of protein kinase activity]
Show all
259 aa
27.7 kDa
No 0
DBNDD2-207
ENSP00000361807
ENST00000372722
Q9BQY9
[Direct mapping] Dysbindin domain-containing protein 2
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006469 [negative regulation of protein kinase activity]
Show all
112 aa
12.6 kDa
No 0
DBNDD2-208
ENSP00000361808
ENST00000372723
Q9BQY9
[Direct mapping] Dysbindin domain-containing protein 2
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006469 [negative regulation of protein kinase activity]
Show all
161 aa
17.5 kDa
No 0
DBNDD2-209
ENSP00000414161
ENST00000443296
H0Y7N7
[Direct mapping] Dysbindin domain-containing protein 2
Show all
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
Show all
172 aa
18.9 kDa
No 0

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