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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
HPA Brain:13.9 nTPM
FANTOM5:45.2 Scaled Tags Per Million
Pig:17.9 nTPM
Mouse:10.2 nTPM

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

13.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 13.0
2828 Female, age 72, unknown 14.6
2019 Male, age 18, unknown 14.1
2411 Female, age 72, unknown 13.7
1870 Female, age 42, unknown 13.5
2586 Male, age 75, left hemisphere 13.5
1830 Male, age 51, unknown 13.3
1827 Male, age 72, unknown 13.0
1833 Male, age 53, unknown 12.4
2666 Male, age 74, left hemisphere 12.2
2219 Male, age 76, both hemispheres 9.5
Dorsal raphe nucleus
nTPM: 12.7
2750 Male, age 76, both hemispheres 13.6
2298 Female, age 72, unknown 13.1
1828 Male, age 53, unknown 13.0
2016 Female, age 72, unknown 12.2
2047 Male, age 72, unknown 11.3
Inferior colliculus
nTPM: 13.5
1890 Male, age 53, unknown 14.2
2097 Female, age 72, unknown 13.8
1848 Female, age 42, unknown 13.2
2849 Male, age 72, unknown 13.0
Median raphe nucleus
nTPM: 13.4
2220 Male, age 76, midline 13.4
Periaquaductal grey, anterior
nTPM: 12.2
2502 Female, age 75, unknown 12.6
1795 Male, age 51, unknown 12.1
1947 Male, age 18, unknown 12.0
Periaquaductal grey, dorsal
nTPM: 13.9
2850 Male, age 76, both hemispheres 15.4
1831 Male, age 72, unknown 14.6
1840 Male, age 53, unknown 13.2
2464 Female, age 72, unknown 12.5
Periaquaductal grey, lateral
nTPM: 12.8
2140 Male, age 76, both hemispheres 17.0
2053 Male, age 18, unknown 11.6
2272 Male, age 74, both hemispheres 9.7
Pretectal area
nTPM: 12.6
2667 Female, age 75, unknown 13.8
2316 Male, age 76, right hemisphere 13.7
2407 Male, age 75, both hemispheres 13.1
2007 Male, age 72, unknown 12.9
1816 Male, age 51, unknown 12.7
1815 Male, age 53, unknown 12.6
2825 Male, age 18, unknown 12.1
1944 Female, age 72, unknown 12.0
2224 Female, age 72, unknown 11.9
2273 Male, age 74, both hemispheres 11.8
1817 Female, age 42, unknown 11.7
Red nucleus
nTPM: 13.3
2227 Male, age 72, unknown 15.1
2769 Male, age 72, unknown 14.6
2503 Female, age 72, unknown 14.2
1904 Male, age 53, unknown 13.8
2785 Male, age 18, unknown 13.8
2588 Male, age 74, left hemisphere 13.7
1954 Female, age 42, unknown 13.5
1821 Female, age 72, unknown 12.9
1865 Male, age 51, unknown 12.5
2823 Male, age 76, right hemisphere 12.2
2725 Female, age 75, unknown 12.0
2584 Male, age 75, left hemisphere 11.8
Substantia nigra
nTPM: 11.4
2665 Male, age 74, both hemispheres 14.4
2583 Male, age 75, right hemisphere 13.4
1889 Female, age 72, unknown 12.9
1916 Female, age 42, unknown 12.5
1851 Male, age 51, unknown 11.8
2699 Male, age 18, unknown 10.8
2590 Female, age 75, unknown 10.5
1941 Male, age 53, unknown 10.0
2241 Male, age 72, unknown 9.7
2409 Female, age 72, unknown 8.4
Superior colliculus
nTPM: 12.9
1796 Male, age 53, unknown 14.1
2668 Female, age 75, unknown 13.7
2261 Male, age 18, unknown 13.5
2664 Male, age 75, both hemispheres 13.5
1895 Male, age 76, right hemisphere 12.8
1995 Male, age 72, unknown 12.8
2087 Female, age 72, unknown 12.6
2587 Male, age 74, left hemisphere 12.5
1839 Male, age 51, unknown 11.9
1913 Female, age 42, unknown 11.8
Ventral tegmental area
nTPM: 12.1
2223 Female, age 72, unknown 13.2
1942 Male, age 51, unknown 12.9
2021 Male, age 53, unknown 12.2
1915 Female, age 42, unknown 11.9
2218 Male, age 76, both hemispheres 11.8
2410 Female, age 72, unknown 10.8

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

45.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 45.2
FF:10158-103A5 76 years, female 45.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

17.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 14.0
Samples: 4

Max nTPM: 17.3
Min nTPM: 7.4
Sample A Female 17.3
Sample B Female 16.9
Sample C Male 7.4
Sample D Male 14.3
Midbrain
nTPM: 17.9
Samples: 4

Max nTPM: 23.1
Min nTPM: 14.1
Sample A Female 23.1
Sample B Female 19.4
Sample C Male 14.1
Sample D Male 15.0
Periaqueductal gray
nTPM: 16.5
Samples: 3

Max nTPM: 18.3
Min nTPM: 14.9
Sample B Female 16.3
Sample C Male 18.3
Sample D Male 14.9
Superior colliculi
nTPM: 15.1
Samples: 4

Max nTPM: 16.4
Min nTPM: 13.2
Sample A Female 15.9
Sample B Female 16.4
Sample C Male 13.2
Sample D Male 14.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

10.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 10.2
Samples: 4

Max nTPM: 10.6
Min nTPM: 9.3
Sample A Male 9.3
Sample B Male 10.6
Sample C Female 10.5
Sample D Female 10.2

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