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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:127.6 nTPM
HPA Brain:78.0 nTPM
GTEx:127.6 nTPM
FANTOM5:127.3 Scaled Tags Per Million
Pig:112.8 nTPM
Mouse:196.1 nTPM
Allen mouse:5.5 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

78.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 67.0
2586 Male, age 75, left hemisphere 86.5
2666 Male, age 74, left hemisphere 76.2
1870 Female, age 42, unknown 73.2
1827 Male, age 72, unknown 68.8
1833 Male, age 53, unknown 64.1
2019 Male, age 18, unknown 62.7
2411 Female, age 72, unknown 61.9
1830 Male, age 51, unknown 61.8
2828 Female, age 72, unknown 60.1
2219 Male, age 76, both hemispheres 55.3
Dorsal raphe nucleus
nTPM: 74.2
2298 Female, age 72, unknown 84.7
1828 Male, age 53, unknown 78.5
2047 Male, age 72, unknown 73.1
2750 Male, age 76, both hemispheres 68.4
2016 Female, age 72, unknown 66.1
Inferior colliculus
nTPM: 68.8
2097 Female, age 72, unknown 73.8
1848 Female, age 42, unknown 70.9
2849 Male, age 72, unknown 65.6
1890 Male, age 53, unknown 65.0
Median raphe nucleus
nTPM: 70.8
2220 Male, age 76, midline 70.8
Periaquaductal grey, anterior
nTPM: 78.0
1947 Male, age 18, unknown 82.2
2502 Female, age 75, unknown 78.8
1795 Male, age 51, unknown 73.0
Periaquaductal grey, dorsal
nTPM: 66.8
1840 Male, age 53, unknown 76.9
1831 Male, age 72, unknown 65.2
2850 Male, age 76, both hemispheres 64.1
2464 Female, age 72, unknown 60.9
Periaquaductal grey, lateral
nTPM: 63.4
2053 Male, age 18, unknown 64.6
2140 Male, age 76, both hemispheres 64.1
2272 Male, age 74, both hemispheres 61.5
Pretectal area
nTPM: 72.1
1944 Female, age 72, unknown 82.4
1816 Male, age 51, unknown 80.5
1817 Female, age 42, unknown 80.5
2007 Male, age 72, unknown 77.0
2224 Female, age 72, unknown 73.9
2825 Male, age 18, unknown 72.8
1815 Male, age 53, unknown 71.1
2273 Male, age 74, both hemispheres 67.8
2667 Female, age 75, unknown 67.5
2407 Male, age 75, both hemispheres 63.7
2316 Male, age 76, right hemisphere 56.3
Red nucleus
nTPM: 65.6
1821 Female, age 72, unknown 78.3
2584 Male, age 75, left hemisphere 69.9
2725 Female, age 75, unknown 68.2
2588 Male, age 74, left hemisphere 67.6
2785 Male, age 18, unknown 65.8
2227 Male, age 72, unknown 65.4
2503 Female, age 72, unknown 64.9
1865 Male, age 51, unknown 64.2
2769 Male, age 72, unknown 64.0
1954 Female, age 42, unknown 63.7
1904 Male, age 53, unknown 59.6
2823 Male, age 76, right hemisphere 56.0
Substantia nigra
nTPM: 76.8
1916 Female, age 42, unknown 89.4
2241 Male, age 72, unknown 85.6
2665 Male, age 74, both hemispheres 81.9
1851 Male, age 51, unknown 81.0
1941 Male, age 53, unknown 79.4
2590 Female, age 75, unknown 72.6
1889 Female, age 72, unknown 71.8
2699 Male, age 18, unknown 69.6
2583 Male, age 75, right hemisphere 68.3
2409 Female, age 72, unknown 68.1
Superior colliculus
nTPM: 70.5
2664 Male, age 75, both hemispheres 78.5
2087 Female, age 72, unknown 75.1
2261 Male, age 18, unknown 74.7
2668 Female, age 75, unknown 74.5
2587 Male, age 74, left hemisphere 74.3
1796 Male, age 53, unknown 70.9
1839 Male, age 51, unknown 70.0
1895 Male, age 76, right hemisphere 63.1
1995 Male, age 72, unknown 62.3
1913 Female, age 42, unknown 61.7
Ventral tegmental area
nTPM: 73.1
1915 Female, age 42, unknown 80.6
2223 Female, age 72, unknown 76.0
2410 Female, age 72, unknown 75.9
1942 Male, age 51, unknown 72.0
2021 Male, age 53, unknown 68.8
2218 Male, age 76, both hemispheres 64.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

127.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 127.6
Samples: 139

Max nTPM: 235.3
Min nTPM: 79.5
Std nTPM: 22.9
Median nTPM: 125.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 235.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 200.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 198.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 177.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 166.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 164.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 163.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 163.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 162.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 160.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 159.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 159.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 157.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 155.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 155.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 154.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 153.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 151.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 150.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 150.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 149.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 147.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 147.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 147.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 147.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 147.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 147.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 144.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 144.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 143.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 143.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 142.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 142.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 142.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 141.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 141.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 140.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 140.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 137.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 135.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 134.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 134.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 134.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 132.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 132.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 132.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 131.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 131.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 130.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 130.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 129.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 129.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 129.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 129.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 129.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 128.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 128.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 128.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 128.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 128.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 128.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 128.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 127.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 127.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 126.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 126.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 126.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 126.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 125.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 125.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 125.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 125.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 125.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 125.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 124.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 124.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 124.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 123.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 123.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 123.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 123.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 122.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 121.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 121.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 121.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 120.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 120.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 120.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 120.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 119.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 118.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 118.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 118.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 118.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 117.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 116.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 116.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 116.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 116.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 114.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 113.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 112.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 112.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 112.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 112.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 112.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 110.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 109.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 109.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 108.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 108.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 108.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 108.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 106.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 106.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 106.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 106.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 105.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 105.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 104.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 104.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 103.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 103.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 103.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 102.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 102.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 100.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 100.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 99.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 97.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 96.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 95.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 94.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 93.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 91.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 90.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 87.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 86.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 79.5
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

127.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 127.3
FF:10158-103A5 76 years, female 127.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

112.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 112.8
Samples: 4

Max nTPM: 148.6
Min nTPM: 87.6
Sample A Female 148.6
Sample B Female 108.6
Sample C Male 106.3
Sample D Male 87.6
Midbrain
nTPM: 109.4
Samples: 4

Max nTPM: 145.5
Min nTPM: 84.1
Sample A Female 145.5
Sample B Female 110.1
Sample C Male 97.8
Sample D Male 84.1
Periaqueductal gray
nTPM: 88.5
Samples: 3

Max nTPM: 94.0
Min nTPM: 79.7
Sample B Female 91.9
Sample C Male 94.0
Sample D Male 79.7
Superior colliculi
nTPM: 103.0
Samples: 4

Max nTPM: 120.8
Min nTPM: 91.3
Sample A Female 120.8
Sample B Female 98.1
Sample C Male 101.8
Sample D Male 91.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

196.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 196.1
Samples: 4

Max nTPM: 203.3
Min nTPM: 188.0
Sample A Male 203.3
Sample B Male 188.0
Sample C Female 191.6
Sample D Female 201.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

5.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 5.5
69445415 Antisense, RP_050419_01_B02, Mouse strain C57BL/6J (56 days, male) 7.7
74988744 Antisense, RP_060315_04_B12, Mouse strain C57BL/6J (56 days, male) 3.4

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