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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
HPA Brain:190.2 nTPM
FANTOM5:92.7 Scaled Tags Per Million
Pig:84.7 nTPM
Mouse:57.0 nTPM
Allen mouse:5.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

190.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 190.2
2586 Male, age 75, left hemisphere 300.5
2666 Male, age 74, left hemisphere 227.7
1827 Male, age 72, unknown 215.8
2828 Female, age 72, unknown 193.4
2219 Male, age 76, both hemispheres 175.8
1830 Male, age 51, unknown 170.5
1833 Male, age 53, unknown 169.7
1870 Female, age 42, unknown 169.0
2019 Male, age 18, unknown 145.6
2411 Female, age 72, unknown 133.7
Dorsal raphe nucleus
nTPM: 155.2
2047 Male, age 72, unknown 171.2
1828 Male, age 53, unknown 161.2
2750 Male, age 76, both hemispheres 156.2
2298 Female, age 72, unknown 146.9
2016 Female, age 72, unknown 140.8
Inferior colliculus
nTPM: 175.2
2849 Male, age 72, unknown 212.2
1890 Male, age 53, unknown 170.9
1848 Female, age 42, unknown 163.7
2097 Female, age 72, unknown 153.8
Median raphe nucleus
nTPM: 164.0
2220 Male, age 76, midline 164.0
Periaquaductal grey, anterior
nTPM: 184.1
1947 Male, age 18, unknown 190.7
1795 Male, age 51, unknown 188.1
2502 Female, age 75, unknown 173.4
Periaquaductal grey, dorsal
nTPM: 174.3
2850 Male, age 76, both hemispheres 188.2
1840 Male, age 53, unknown 185.5
1831 Male, age 72, unknown 182.4
2464 Female, age 72, unknown 140.9
Periaquaductal grey, lateral
nTPM: 153.0
2140 Male, age 76, both hemispheres 169.4
2053 Male, age 18, unknown 163.2
2272 Male, age 74, both hemispheres 126.5
Pretectal area
nTPM: 184.8
2407 Male, age 75, both hemispheres 238.9
1816 Male, age 51, unknown 231.2
1817 Female, age 42, unknown 197.3
1944 Female, age 72, unknown 196.5
1815 Male, age 53, unknown 190.5
2007 Male, age 72, unknown 190.4
2825 Male, age 18, unknown 187.6
2667 Female, age 75, unknown 179.0
2316 Male, age 76, right hemisphere 157.2
2224 Female, age 72, unknown 149.8
2273 Male, age 74, both hemispheres 114.9
Red nucleus
nTPM: 164.2
2584 Male, age 75, left hemisphere 250.2
2588 Male, age 74, left hemisphere 190.6
2725 Female, age 75, unknown 171.5
2823 Male, age 76, right hemisphere 163.6
2785 Male, age 18, unknown 155.8
2769 Male, age 72, unknown 153.0
1954 Female, age 42, unknown 152.8
1904 Male, age 53, unknown 151.5
2227 Male, age 72, unknown 150.3
1821 Female, age 72, unknown 149.8
2503 Female, age 72, unknown 144.4
1865 Male, age 51, unknown 137.5
Substantia nigra
nTPM: 168.6
2665 Male, age 74, both hemispheres 216.8
2583 Male, age 75, right hemisphere 198.9
1916 Female, age 42, unknown 187.4
2699 Male, age 18, unknown 179.4
1889 Female, age 72, unknown 178.8
2590 Female, age 75, unknown 166.9
1851 Male, age 51, unknown 164.2
1941 Male, age 53, unknown 164.0
2241 Male, age 72, unknown 126.5
2409 Female, age 72, unknown 102.9
Superior colliculus
nTPM: 182.9
2664 Male, age 75, both hemispheres 258.0
2261 Male, age 18, unknown 191.8
2087 Female, age 72, unknown 187.7
2668 Female, age 75, unknown 182.5
1796 Male, age 53, unknown 181.5
1839 Male, age 51, unknown 180.0
1913 Female, age 42, unknown 167.9
1895 Male, age 76, right hemisphere 162.2
2587 Male, age 74, left hemisphere 161.7
1995 Male, age 72, unknown 155.7
Ventral tegmental area
nTPM: 162.0
2223 Female, age 72, unknown 171.8
2218 Male, age 76, both hemispheres 171.0
1915 Female, age 42, unknown 168.3
2021 Male, age 53, unknown 165.1
1942 Male, age 51, unknown 160.9
2410 Female, age 72, unknown 135.1

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

92.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 92.7
FF:10158-103A5 76 years, female 92.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

84.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 76.3
Samples: 4

Max nTPM: 90.8
Min nTPM: 66.2
Sample A Female 80.7
Sample B Female 66.2
Sample C Male 90.8
Sample D Male 67.5
Midbrain
nTPM: 84.8
Samples: 4

Max nTPM: 107.9
Min nTPM: 61.3
Sample A Female 76.0
Sample B Female 61.3
Sample C Male 107.9
Sample D Male 93.8
Periaqueductal gray
nTPM: 67.5
Samples: 3

Max nTPM: 76.0
Min nTPM: 63.1
Sample B Female 63.1
Sample C Male 76.0
Sample D Male 63.4
Superior colliculi
nTPM: 82.0
Samples: 4

Max nTPM: 94.7
Min nTPM: 66.8
Sample A Female 81.2
Sample B Female 66.8
Sample C Male 85.2
Sample D Male 94.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

57.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 57.0
Samples: 4

Max nTPM: 63.4
Min nTPM: 49.2
Sample A Male 49.2
Sample B Male 56.3
Sample C Female 59.1
Sample D Female 63.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

5.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 5.8
68797673 Antisense, RP_050210_02_H08, Mouse strain C57BL/6J (56 days, male) 5.8

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