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Category
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  • STRUCT & INT

  • PRRC2B
CANCER RENAL CANCER Show tissue menu
BREAST CANCER CARCINOID CERVICAL CANCER COLORECTAL CANCER ENDOMETRIAL CANCER GLIOMA HEAD AND NECK CANCER LIVER CANCER LUNG CANCER LYMPHOMA
MELANOMA OVARIAN CANCER PANCREATIC CANCER PROSTATE CANCER RENAL CANCER SKIN CANCER STOMACH CANCER TESTIS CANCER THYROID CANCER UROTHELIAL CANCER
KICH TCGA KIRC TCGA KIRC VALIDATION KIRP TCGA PROTEIN RCC CPTAC PROTEIN EXPRESSION
ANTIBODIES
AND
VALIDATION
Dictionary
Renal cancer
Human cancer
Kidney chromophobe
Kidney renal clear cell carcinoma
Kidney renal papillary cell carcinoma
KIDNEY CHROMOPHOBE (TCGA) - Interactive survival scatter ploti

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisi

Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.

  Survival analysis data not available.
KIDNEY RENAL CLEAR CELL CARCINOMA (TCGA) - Interactive survival scatter ploti

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisi

Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.

  Survival analysis data not available.
KIDNEY RENAL CLEAR CELL CARCINOMA (VALIDATION) - Interactive survival scatter ploti

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisi

Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.

  Survival analysis data not available.
KIDNEY RENAL PAPILLARY CELL CARCINOMA (TCGA) - Interactive survival scatter ploti

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisi

Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.

  Survival analysis data not available.
RENAL CELL CARCINOMA - Protein relative expression (CPTAC)
Number of samples 194
Samples
Sample ID Sample type nRPX
CPT0001270001 Normal 0.4
CPT0078800003 Tumor 0.4
CPT0078830003 Tumor 0.3
CPT0079410003 Tumor 0.3
CPT0065430003 Tumor 0.3
CPT0065870003 Tumor 0.3
CPT0071150004 Tumor 0.3
CPT0078660003 Tumor 0.3
CPT0092190003 Normal 0.3
CPT0017450001 Normal 0.3
CPT0017850003 Tumor 0.3
CPT0015910003 Tumor 0.3
CPT0078530001 Normal 0.3
CPT0075170001 Normal 0.2
CPT0079510001 Normal 0.2
CPT0088630003 Tumor 0.2
CPT0026410003 Tumor 0.2
CPT0089460004 Tumor 0.2
CPT0084590001 Normal 0.2
CPT0010120001 Normal 0.2
CPT0000660001 Normal 0.2
CPT0079180003 Tumor 0.2
CPT0085670003 Tumor 0.2
CPT0088970003 Tumor 0.2
CPT0009060003 Tumor 0.2
CPT0078840001 Normal 0.2
CPT0012370003 Tumor 0.2
CPT0023350003 Tumor 0.2
CPT0063320003 Tumor 0.2
CPT0014370004 Tumor 0.2
CPT0014130001 Normal 0.2
CPT0092740003 Normal 0.2
CPT0006630003 Tumor 0.2
CPT0076350001 Normal 0.2
CPT0001190001 Normal 0.2
CPT0077490003 Tumor 0.2
CPT0088760003 Tumor 0.1
CPT0007320003 Tumor 0.1
CPT0000780007 Tumor 0.1
CPT0010110003 Tumor 0.1
CPT0075720003 Tumor 0.1
CPT0025350003 Tumor 0.1
CPT0007870001 Normal 0.1
CPT0001550001 Normal 0.1
CPT0086970003 Normal 0.1
CPT0010160003 Tumor 0.1
CPT0019130003 Tumor 0.1
CPT0086890003 Normal 0.1
CPT0065450001 Normal 0.1
CPT0079430001 Normal 0.1
CPT0026420001 Normal 0.1
CPT0002270011 Tumor 0.1
CPT0089040001 Normal 0.1
CPT0088780001 Normal 0.1
CPT0025060001 Normal 0.1
CPT0001230001 Normal 0.1
CPT0006440003 Tumor 0.1
CPT0006530001 Normal 0.1
CPT0088640003 Normal 0.1
CPT0086370003 Normal 0.1
CPT0000870016 Tumor 0.1
CPT0001350001 Normal 0.1
CPT0023710001 Normal 0.1
CPT0012570003 Normal 0.1
CPT0014470001 Normal 0.1
CPT0015730003 Tumor 0.1
CPT0018250001 Normal 0.1
CPT0025610001 Normal 0.1
CPT0011410003 Tumor 0.1
CPT0088920001 Normal 0.1
CPT0077320001 Normal 0.1
CPT0007470001 Normal 0.1
CPT0079270003 Tumor 0.1
CPT0086830003 Normal 0.1
CPT0017410003 Tumor 0.1
CPT0069160003 Tumor 0.1
CPT0092310003 Normal 0.1
CPT0088500001 Normal 0.1
CPT0064400001 Normal 0.1
CPT0020020001 Normal 0.1
CPT0066430001 Normal 0.1
CPT0020130001 Normal 0.1
CPT0079380003 Tumor 0.1
CPT0009080003 Normal 0.1
CPT0063640001 Normal 0.1
CPT0012640003 Normal 0.1
CPT0000790001 Normal 0.1
CPT0063330001 Normal 0.1
CPT0088900003 Tumor 0.1
CPT0019160001 Normal 0.1
CPT0092160003 Tumor 0.1
CPT0089480003 Normal 0.1
CPT0001220008 Tumor 0.1
CPT0078930003 Tumor 0.1
CPT0000890001 Normal 0.1
CPT0086870003 Tumor 0.1
CPT0001540009 Tumor 0.1
CPT0077140001 Normal 0.1
CPT0078670001 Normal 0.1
CPT0065750003 Tumor 0.1
CPT0023360001 Normal 0.0
CPT0077110003 Tumor 0.0
CPT0087050003 Normal 0.0
CPT0001180009 Tumor 0.0
CPT0078940001 Normal 0.0
CPT0001260009 Tumor 0.0
CPT0092800003 Normal 0.0
CPT0084560003 Tumor 0.0
CPT0086360003 Tumor 0.0
CPT0088690003 Tumor 0.0
CPT0092790003 Tumor 0.0
CPT0006730001 Normal 0.0
CPT0081620001 Normal 0.0
CPT0079480003 Tumor 0.0
CPT0013790003 Normal 0.0
CPT0086820003 Tumor 0.0
CPT0012920003 Normal 0.0
CPT0012770003 Normal 0.0
CPT0075570001 Normal 0.0
CPT0075130003 Tumor 0.0
CPT0092730003 Tumor 0.0
CPT0086030003 Tumor 0.0
CPT0012550003 Tumor 0.0
CPT0065810003 Tumor 0.0
CPT0065820001 Normal 0.0
CPT0025920001 Normal 0.0
CPT0020120003 Tumor 0.0
CPT0081990003 Tumor 0.0
CPT0009020003 Normal 0.0
CPT0069190001 Normal 0.0
CPT0001510001 Normal 0.0
CPT0079000001 Normal 0.0
CPT0087040003 Tumor 0.0
CPT0077500001 Normal 0.0
CPT0009000003 Tumor 0.0
CPT0079300001 Normal 0.0
CPT0088710001 Normal 0.0
CPT0066520001 Normal 0.0
CPT0002370001 Normal 0.0
CPT0012290003 Normal 0.0
CPT0066480003 Tumor 0.0
CPT0082010001 Normal 0.0
CPT0006950001 Normal 0.0
CPT0001340003 Tumor 0.0
CPT0010170001 Normal 0.0
CPT0024680001 Normal 0.0
CPT0081600003 Tumor 0.0
CPT0079230003 Tumor 0.0
CPT0001500009 Tumor -0.1
CPT0012090003 Normal -0.1
CPT0015810003 Tumor -0.1
CPT0012900004 Tumor -0.1
CPT0088570001 Normal -0.1
CPT0025580004 Tumor -0.1
CPT0066470004 Tumor -0.1
CPT0006900003 Tumor -0.1
CPT0023690003 Tumor -0.1
CPT0089020003 Tumor -0.1
CPT0064370003 Tumor -0.1
CPT0025880003 Tumor -0.1
CPT0069000003 Tumor -0.1
CPT0012670003 Tumor -0.1
CPT0014350001 Normal -0.1
CPT0069010001 Normal -0.1
CPT0011240003 Tumor -0.1
CPT0000640003 Tumor -0.1
CPT0025170003 Tumor -0.1
CPT0088480003 Tumor -0.1
CPT0007860003 Tumor -0.1
CPT0012080003 Tumor -0.1
CPT0002350011 Tumor -0.1
CPT0075560003 Tumor -0.1
CPT0088550004 Tumor -0.2
CPT0025110003 Tumor -0.2
CPT0078990003 Tumor -0.2
CPT0086950003 Tumor -0.2
CPT0025290003 Tumor -0.2
CPT0014450004 Tumor -0.2
CPT0012280003 Tumor -0.2
CPT0065690003 Tumor -0.2
CPT0019990003 Tumor -0.2
CPT0021240003 Tumor -0.3
CPT0014160003 Tumor -0.3
CPT0012180003 Tumor -0.3
CPT0065930003 Tumor -0.3
CPT0025230003 Tumor -0.3
CPT0081880003 Tumor -0.3
CPT0092290003 Tumor -0.3
CPT0077310003 Tumor -0.3
CPT0063630003 Tumor -0.3
CPT0078510003 Tumor -0.4
CPT0024670003 Tumor -0.5
CPT0025050003 Tumor -0.5
CPT0076330003 Tumor -0.5
Show allShow less
RENAL CANCER - Protein expressioni

A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.

Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

 

Antibody stainingi

Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.

Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.


Antibody HPA021022
 Staining
  High
  Medium
  Low
  Not detected
 Intensity
  Strong
  Moderate
  Weak
  Negative
 Quantity
  >75%
  75%-25%
  <25%
  None
 Location
  Nuclear
  Cytoplasmic/membranous
  Cytoplasmic/membranous,nuclear
  None
Adenocarcinoma, NOS

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The Human Protein Atlas project is funded
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