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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:45.6 nTPM
HPA Brain:64.3 nTPM
GTEx:45.6 nTPM
FANTOM5:581.1 Scaled Tags Per Million
Pig:60.0 nTPM
Mouse:6.8 nTPM
Allen mouse:0.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

64.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 43.8
1870 Female, age 42, unknown 75.1
2411 Female, age 72, unknown 57.0
1830 Male, age 51, unknown 52.9
1833 Male, age 53, unknown 50.5
2586 Male, age 75, left hemisphere 38.9
2828 Female, age 72, unknown 38.4
2019 Male, age 18, unknown 36.3
1827 Male, age 72, unknown 33.3
2666 Male, age 74, left hemisphere 29.2
2219 Male, age 76, both hemispheres 26.8
Dorsal raphe nucleus
nTPM: 41.2
2016 Female, age 72, unknown 51.0
2750 Male, age 76, both hemispheres 50.9
1828 Male, age 53, unknown 38.7
2298 Female, age 72, unknown 34.1
2047 Male, age 72, unknown 31.2
Inferior colliculus
nTPM: 38.5
1848 Female, age 42, unknown 44.9
2849 Male, age 72, unknown 39.1
1890 Male, age 53, unknown 35.8
2097 Female, age 72, unknown 34.2
Median raphe nucleus
nTPM: 64.3
2220 Male, age 76, midline 64.3
Periaquaductal grey, anterior
nTPM: 31.8
1947 Male, age 18, unknown 33.7
2502 Female, age 75, unknown 33.3
1795 Male, age 51, unknown 28.4
Periaquaductal grey, dorsal
nTPM: 43.3
2850 Male, age 76, both hemispheres 59.7
2464 Female, age 72, unknown 45.6
1831 Male, age 72, unknown 34.1
1840 Male, age 53, unknown 33.9
Periaquaductal grey, lateral
nTPM: 44.8
2140 Male, age 76, both hemispheres 59.2
2053 Male, age 18, unknown 37.9
2272 Male, age 74, both hemispheres 37.2
Pretectal area
nTPM: 34.3
2667 Female, age 75, unknown 44.8
2224 Female, age 72, unknown 43.3
2825 Male, age 18, unknown 41.5
1815 Male, age 53, unknown 38.0
2316 Male, age 76, right hemisphere 36.7
1817 Female, age 42, unknown 33.8
2273 Male, age 74, both hemispheres 31.4
2407 Male, age 75, both hemispheres 27.3
1944 Female, age 72, unknown 27.2
1816 Male, age 51, unknown 27.0
2007 Male, age 72, unknown 26.7
Red nucleus
nTPM: 53.7
1821 Female, age 72, unknown 65.3
1954 Female, age 42, unknown 62.6
1865 Male, age 51, unknown 62.4
1904 Male, age 53, unknown 61.9
2227 Male, age 72, unknown 59.2
2503 Female, age 72, unknown 59.2
2769 Male, age 72, unknown 59.0
2823 Male, age 76, right hemisphere 50.0
2785 Male, age 18, unknown 44.1
2588 Male, age 74, left hemisphere 42.3
2725 Female, age 75, unknown 42.1
2584 Male, age 75, left hemisphere 36.5
Substantia nigra
nTPM: 46.9
2699 Male, age 18, unknown 78.7
2409 Female, age 72, unknown 58.1
2241 Male, age 72, unknown 53.3
1851 Male, age 51, unknown 51.6
1889 Female, age 72, unknown 43.9
2590 Female, age 75, unknown 42.6
1916 Female, age 42, unknown 41.4
2583 Male, age 75, right hemisphere 35.6
2665 Male, age 74, both hemispheres 35.2
1941 Male, age 53, unknown 29.0
Superior colliculus
nTPM: 42.2
1913 Female, age 42, unknown 83.2
1995 Male, age 72, unknown 65.7
2587 Male, age 74, left hemisphere 42.0
1796 Male, age 53, unknown 38.9
1839 Male, age 51, unknown 38.7
2668 Female, age 75, unknown 37.5
1895 Male, age 76, right hemisphere 34.2
2087 Female, age 72, unknown 33.0
2261 Male, age 18, unknown 27.4
2664 Male, age 75, both hemispheres 21.7
Ventral tegmental area
nTPM: 47.4
2021 Male, age 53, unknown 63.6
2410 Female, age 72, unknown 52.7
2223 Female, age 72, unknown 48.5
1915 Female, age 42, unknown 41.2
2218 Male, age 76, both hemispheres 39.8
1942 Male, age 51, unknown 38.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

45.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 45.6
Samples: 139

Max nTPM: 195.4
Min nTPM: 9.1
Std nTPM: 34.3
Median nTPM: 33.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 195.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 156.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 155.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 144.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 132.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 131.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 119.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 117.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 115.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 102.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 101.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 99.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 93.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 93.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 93.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 92.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 87.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 83.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 82.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 81.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 78.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 76.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 75.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 73.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 70.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 70.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 68.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 66.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 65.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 64.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 63.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 63.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 62.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 61.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 60.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 60.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 60.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 59.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 58.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 58.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 57.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 56.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 51.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 51.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 50.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 46.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 46.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 44.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 43.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 42.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 42.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 42.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 41.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 41.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 40.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 40.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 40.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 40.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 39.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 39.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 38.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 38.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 37.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 36.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 36.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 35.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 34.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 34.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 34.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 33.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 32.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 32.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 31.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 31.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 30.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 30.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 28.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 28.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 28.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 28.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 27.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 27.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 27.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 27.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 27.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 26.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 26.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 25.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 25.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 25.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 24.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 24.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 24.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 24.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 23.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 23.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 23.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 23.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 23.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 23.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 22.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 22.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 22.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 22.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 22.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 22.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 22.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 21.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 21.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 20.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 20.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 20.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 20.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 19.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 19.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 19.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 19.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 18.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 18.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 18.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 17.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 17.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 16.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 16.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 15.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 15.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 15.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 15.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 14.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 13.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 13.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 12.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 12.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 12.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 12.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 11.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 10.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 9.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 9.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

581.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 581.1
FF:10158-103A5 76 years, female 581.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

60.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 50.4
Samples: 4

Max nTPM: 65.7
Min nTPM: 31.6
Sample A Female 31.6
Sample B Female 55.6
Sample C Male 48.7
Sample D Male 65.7
Midbrain
nTPM: 49.4
Samples: 4

Max nTPM: 73.4
Min nTPM: 29.2
Sample A Female 52.3
Sample B Female 73.4
Sample C Male 42.7
Sample D Male 29.2
Periaqueductal gray
nTPM: 60.0
Samples: 3

Max nTPM: 70.4
Min nTPM: 49.6
Sample B Female 70.4
Sample C Male 60.1
Sample D Male 49.6
Superior colliculi
nTPM: 51.1
Samples: 4

Max nTPM: 94.7
Min nTPM: 27.0
Sample A Female 27.0
Sample B Female 94.7
Sample C Male 41.6
Sample D Male 41.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

6.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 6.8
Samples: 4

Max nTPM: 7.6
Min nTPM: 6.2
Sample A Male 6.2
Sample B Male 6.9
Sample C Female 7.6
Sample D Female 6.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.0
68546548 Antisense, RP_050120_02_F10, Mouse strain C57BL/6J (56 days, male) 0.0

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