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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:116.7 nTPM
HPA Brain:438.3 nTPM
GTEx:116.7 nTPM
FANTOM5:156.9 Scaled Tags Per Million
Pig:119.0 nTPM
Mouse:209.3 nTPM
Allen mouse:9.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

438.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 361.9
2586 Male, age 75, left hemisphere 566.2
2666 Male, age 74, left hemisphere 465.8
1827 Male, age 72, unknown 388.6
2219 Male, age 76, both hemispheres 375.2
2828 Female, age 72, unknown 346.2
2411 Female, age 72, unknown 314.8
1870 Female, age 42, unknown 313.3
1833 Male, age 53, unknown 309.1
1830 Male, age 51, unknown 272.2
2019 Male, age 18, unknown 267.9
Dorsal raphe nucleus
nTPM: 334.6
2047 Male, age 72, unknown 396.7
2298 Female, age 72, unknown 388.7
1828 Male, age 53, unknown 313.9
2750 Male, age 76, both hemispheres 299.6
2016 Female, age 72, unknown 273.9
Inferior colliculus
nTPM: 371.5
2097 Female, age 72, unknown 395.6
1848 Female, age 42, unknown 395.3
2849 Male, age 72, unknown 376.6
1890 Male, age 53, unknown 318.6
Median raphe nucleus
nTPM: 413.3
2220 Male, age 76, midline 413.3
Periaquaductal grey, anterior
nTPM: 438.3
2502 Female, age 75, unknown 495.5
1795 Male, age 51, unknown 417.9
1947 Male, age 18, unknown 401.4
Periaquaductal grey, dorsal
nTPM: 329.5
1840 Male, age 53, unknown 411.0
2464 Female, age 72, unknown 330.1
1831 Male, age 72, unknown 319.8
2850 Male, age 76, both hemispheres 257.2
Periaquaductal grey, lateral
nTPM: 249.3
2053 Male, age 18, unknown 299.9
2140 Male, age 76, both hemispheres 253.6
2272 Male, age 74, both hemispheres 194.6
Pretectal area
nTPM: 341.3
1816 Male, age 51, unknown 462.3
2007 Male, age 72, unknown 413.3
1944 Female, age 72, unknown 410.9
1817 Female, age 42, unknown 405.1
1815 Male, age 53, unknown 363.5
2224 Female, age 72, unknown 361.0
2825 Male, age 18, unknown 331.7
2407 Male, age 75, both hemispheres 302.1
2667 Female, age 75, unknown 278.1
2316 Male, age 76, right hemisphere 244.4
2273 Male, age 74, both hemispheres 182.4
Red nucleus
nTPM: 253.9
2584 Male, age 75, left hemisphere 370.3
2785 Male, age 18, unknown 288.0
2588 Male, age 74, left hemisphere 277.5
2503 Female, age 72, unknown 274.4
2227 Male, age 72, unknown 255.3
2769 Male, age 72, unknown 254.8
1821 Female, age 72, unknown 250.0
2725 Female, age 75, unknown 245.0
1954 Female, age 42, unknown 222.4
1865 Male, age 51, unknown 209.9
1904 Male, age 53, unknown 209.2
2823 Male, age 76, right hemisphere 189.8
Substantia nigra
nTPM: 372.5
2665 Male, age 74, both hemispheres 499.3
1916 Female, age 42, unknown 446.2
1851 Male, age 51, unknown 418.6
1941 Male, age 53, unknown 395.2
1889 Female, age 72, unknown 383.8
2699 Male, age 18, unknown 345.9
2583 Male, age 75, right hemisphere 339.9
2241 Male, age 72, unknown 327.1
2590 Female, age 75, unknown 294.0
2409 Female, age 72, unknown 274.9
Superior colliculus
nTPM: 357.2
2664 Male, age 75, both hemispheres 499.0
2668 Female, age 75, unknown 462.4
1796 Male, age 53, unknown 435.0
2261 Male, age 18, unknown 373.1
2087 Female, age 72, unknown 370.8
1839 Male, age 51, unknown 344.3
1895 Male, age 76, right hemisphere 328.6
2587 Male, age 74, left hemisphere 286.8
1913 Female, age 42, unknown 245.9
1995 Male, age 72, unknown 226.1
Ventral tegmental area
nTPM: 392.7
2223 Female, age 72, unknown 427.1
2218 Male, age 76, both hemispheres 413.8
1915 Female, age 42, unknown 403.6
1942 Male, age 51, unknown 398.2
2410 Female, age 72, unknown 365.7
2021 Male, age 53, unknown 348.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

116.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 116.7
Samples: 139

Max nTPM: 358.0
Min nTPM: 48.7
Std nTPM: 48.0
Median nTPM: 104.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 358.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 265.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 253.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 223.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 220.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 215.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 212.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 200.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 199.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 195.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 195.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 192.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 191.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 189.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 188.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 185.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 184.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 181.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 180.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 176.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 175.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 172.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 167.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 165.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 153.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 152.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 146.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 146.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 142.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 142.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 138.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 136.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 135.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 130.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 129.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 128.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 127.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 126.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 126.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 126.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 125.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 123.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 123.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 122.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 121.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 120.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 119.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 117.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 116.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 115.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 115.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 115.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 114.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 114.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 114.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 113.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 113.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 112.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 111.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 111.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 111.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 111.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 110.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 110.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 109.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 108.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 107.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 106.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 104.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 104.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 103.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 103.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 101.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 101.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 101.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 101.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 100.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 99.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 99.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 98.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 98.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 97.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 96.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 95.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 94.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 91.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 91.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 90.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 90.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 89.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 89.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 89.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 88.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 88.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 88.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 88.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 88.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 88.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 87.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 86.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 86.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 86.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 86.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 85.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 85.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 85.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 83.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 83.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 82.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 82.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 81.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 81.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 81.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 81.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 80.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 79.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 79.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 77.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 77.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 77.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 76.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 73.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 73.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 71.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 71.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 70.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 70.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 70.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 68.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 66.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 65.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 62.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 61.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 60.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 59.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 58.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 57.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 55.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 48.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

156.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 156.9
FF:10158-103A5 76 years, female 156.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

119.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 101.9
Samples: 4

Max nTPM: 117.6
Min nTPM: 82.6
Sample A Female 111.8
Sample B Female 82.6
Sample C Male 117.6
Sample D Male 95.5
Midbrain
nTPM: 119.0
Samples: 4

Max nTPM: 159.7
Min nTPM: 84.0
Sample A Female 159.7
Sample B Female 84.0
Sample C Male 129.1
Sample D Male 103.3
Periaqueductal gray
nTPM: 88.2
Samples: 3

Max nTPM: 103.8
Min nTPM: 78.0
Sample B Female 82.9
Sample C Male 103.8
Sample D Male 78.0
Superior colliculi
nTPM: 100.1
Samples: 4

Max nTPM: 112.2
Min nTPM: 73.3
Sample A Female 108.8
Sample B Female 73.3
Sample C Male 106.1
Sample D Male 112.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

209.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 209.3
Samples: 4

Max nTPM: 219.1
Min nTPM: 192.7
Sample A Male 192.7
Sample B Male 219.1
Sample C Female 216.2
Sample D Female 209.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.7
73994671 Antisense, RP_051214_03_E06, Mouse strain C57BL/6J (56 days, male) 11.1
69735222 Antisense, RP_050503_02_C12, Mouse strain C57BL/6J (56 days, male) 8.3

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