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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:132.3 nTPM
HPA Brain:192.7 nTPM
GTEx:132.3 nTPM
FANTOM5:245.0 Scaled Tags Per Million
Pig:194.9 nTPM
Mouse:384.8 nTPM
Allen mouse:10.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

192.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 163.8
1870 Female, age 42, unknown 191.3
1827 Male, age 72, unknown 188.5
2411 Female, age 72, unknown 185.1
1833 Male, age 53, unknown 164.5
2019 Male, age 18, unknown 163.8
1830 Male, age 51, unknown 161.9
2828 Female, age 72, unknown 149.6
2219 Male, age 76, both hemispheres 145.5
2586 Male, age 75, left hemisphere 144.3
2666 Male, age 74, left hemisphere 143.6
Dorsal raphe nucleus
nTPM: 163.1
2298 Female, age 72, unknown 183.2
2016 Female, age 72, unknown 168.5
2750 Male, age 76, both hemispheres 161.5
2047 Male, age 72, unknown 152.3
1828 Male, age 53, unknown 149.7
Inferior colliculus
nTPM: 192.7
2097 Female, age 72, unknown 215.1
1848 Female, age 42, unknown 204.6
2849 Male, age 72, unknown 186.1
1890 Male, age 53, unknown 164.9
Median raphe nucleus
nTPM: 159.5
2220 Male, age 76, midline 159.5
Periaquaductal grey, anterior
nTPM: 183.7
1947 Male, age 18, unknown 194.9
2502 Female, age 75, unknown 187.2
1795 Male, age 51, unknown 169.0
Periaquaductal grey, dorsal
nTPM: 177.3
1840 Male, age 53, unknown 191.4
1831 Male, age 72, unknown 175.3
2464 Female, age 72, unknown 171.9
2850 Male, age 76, both hemispheres 170.5
Periaquaductal grey, lateral
nTPM: 172.7
2053 Male, age 18, unknown 189.4
2272 Male, age 74, both hemispheres 169.6
2140 Male, age 76, both hemispheres 159.2
Pretectal area
nTPM: 186.1
1816 Male, age 51, unknown 207.3
1944 Female, age 72, unknown 205.9
1815 Male, age 53, unknown 196.7
1817 Female, age 42, unknown 192.5
2007 Male, age 72, unknown 192.2
2273 Male, age 74, both hemispheres 189.9
2224 Female, age 72, unknown 185.6
2667 Female, age 75, unknown 181.7
2825 Male, age 18, unknown 175.8
2407 Male, age 75, both hemispheres 166.9
2316 Male, age 76, right hemisphere 153.1
Red nucleus
nTPM: 165.4
1821 Female, age 72, unknown 194.4
2503 Female, age 72, unknown 184.8
2725 Female, age 75, unknown 178.6
1865 Male, age 51, unknown 177.3
1954 Female, age 42, unknown 172.0
1904 Male, age 53, unknown 165.7
2785 Male, age 18, unknown 158.7
2588 Male, age 74, left hemisphere 157.0
2769 Male, age 72, unknown 155.1
2227 Male, age 72, unknown 149.9
2584 Male, age 75, left hemisphere 146.2
2823 Male, age 76, right hemisphere 145.0
Substantia nigra
nTPM: 162.9
1889 Female, age 72, unknown 194.5
2241 Male, age 72, unknown 185.4
2409 Female, age 72, unknown 176.7
1941 Male, age 53, unknown 174.2
2590 Female, age 75, unknown 165.6
2665 Male, age 74, both hemispheres 152.1
1916 Female, age 42, unknown 148.9
2583 Male, age 75, right hemisphere 147.1
1851 Male, age 51, unknown 146.1
2699 Male, age 18, unknown 138.9
Superior colliculus
nTPM: 175.9
1895 Male, age 76, right hemisphere 192.7
2261 Male, age 18, unknown 190.4
1913 Female, age 42, unknown 183.7
1796 Male, age 53, unknown 182.1
2587 Male, age 74, left hemisphere 180.2
1839 Male, age 51, unknown 178.2
2087 Female, age 72, unknown 177.8
1995 Male, age 72, unknown 165.6
2668 Female, age 75, unknown 158.1
2664 Male, age 75, both hemispheres 149.7
Ventral tegmental area
nTPM: 163.2
2410 Female, age 72, unknown 181.2
2223 Female, age 72, unknown 172.2
1942 Male, age 51, unknown 161.2
2021 Male, age 53, unknown 158.2
1915 Female, age 42, unknown 156.9
2218 Male, age 76, both hemispheres 149.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

132.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 132.3
Samples: 139

Max nTPM: 239.3
Min nTPM: 83.5
Std nTPM: 26.1
Median nTPM: 128.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 239.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 231.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 199.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 185.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 184.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 181.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 180.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 179.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 175.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 173.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 171.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 170.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 170.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 169.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 167.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 167.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 165.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 163.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 162.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 162.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 161.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 159.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 158.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 156.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 155.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 154.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 154.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 154.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 151.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 150.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 150.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 149.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 149.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 147.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 145.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 145.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 144.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 140.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 139.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 139.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 138.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 138.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 137.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 137.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 137.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 136.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 136.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 136.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 135.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 134.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 134.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 133.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 132.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 132.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 132.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 131.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 131.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 131.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 131.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 130.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 130.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 129.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 129.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 128.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 128.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 128.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 128.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 128.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 128.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 128.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 128.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 127.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 127.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 127.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 127.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 127.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 126.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 126.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 125.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 125.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 125.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 124.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 123.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 123.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 123.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 123.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 123.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 122.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 121.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 121.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 120.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 120.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 119.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 118.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 118.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 117.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 117.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 117.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 117.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 116.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 116.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 116.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 115.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 114.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 114.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 113.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 113.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 113.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 113.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 112.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 112.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 112.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 110.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 109.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 108.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 108.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 107.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 107.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 106.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 106.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 106.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 105.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 105.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 104.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 104.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 104.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 102.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 102.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 101.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 100.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 100.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 99.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 99.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 95.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 94.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 93.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 93.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 90.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 83.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

245.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 245.0
FF:10158-103A5 76 years, female 245.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

194.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 152.2
Samples: 4

Max nTPM: 177.9
Min nTPM: 128.8
Sample A Female 177.9
Sample B Female 148.2
Sample C Male 153.7
Sample D Male 128.8
Midbrain
nTPM: 194.9
Samples: 4

Max nTPM: 216.8
Min nTPM: 171.8
Sample A Female 192.4
Sample B Female 171.8
Sample C Male 216.8
Sample D Male 198.4
Periaqueductal gray
nTPM: 154.2
Samples: 3

Max nTPM: 161.7
Min nTPM: 149.2
Sample B Female 149.2
Sample C Male 161.7
Sample D Male 151.6
Superior colliculi
nTPM: 183.1
Samples: 4

Max nTPM: 199.9
Min nTPM: 161.0
Sample A Female 190.2
Sample B Female 161.0
Sample C Male 199.9
Sample D Male 181.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

384.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 384.9
Samples: 4

Max nTPM: 393.8
Min nTPM: 369.9
Sample A Male 391.2
Sample B Male 393.8
Sample C Female 384.5
Sample D Female 369.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

10.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.1
67752309 Antisense, RP_040922_01_D07, Mouse strain C57BL/6J (56 days, male) 19.1
68196969 Antisense, RP_040922_01_D07, Mouse strain C57BL/6J (56 days, male) 13.0
314 Antisense, RP_Baylor_103388, Mouse strain C57BL/6J (56 days, male) 1.1

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