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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:63.5 nTPM
HPA Brain:279.2 nTPM
GTEx:63.5 nTPM
FANTOM5:127.7 Scaled Tags Per Million
Pig:412.7 nTPM
Mouse:179.9 nTPM
Allen mouse:1.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

279.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 176.0
2219 Male, age 76, both hemispheres 255.7
2586 Male, age 75, left hemisphere 198.9
2828 Female, age 72, unknown 198.3
1827 Male, age 72, unknown 196.4
1870 Female, age 42, unknown 175.3
2411 Female, age 72, unknown 165.7
1833 Male, age 53, unknown 149.7
2666 Male, age 74, left hemisphere 141.6
1830 Male, age 51, unknown 141.4
2019 Male, age 18, unknown 136.9
Dorsal raphe nucleus
nTPM: 218.0
2298 Female, age 72, unknown 257.1
2047 Male, age 72, unknown 239.8
2016 Female, age 72, unknown 230.0
2750 Male, age 76, both hemispheres 202.9
1828 Male, age 53, unknown 160.4
Inferior colliculus
nTPM: 192.4
2097 Female, age 72, unknown 209.4
1848 Female, age 42, unknown 201.6
1890 Male, age 53, unknown 180.9
2849 Male, age 72, unknown 177.6
Median raphe nucleus
nTPM: 279.2
2220 Male, age 76, midline 279.2
Periaquaductal grey, anterior
nTPM: 237.8
1947 Male, age 18, unknown 291.4
1795 Male, age 51, unknown 221.7
2502 Female, age 75, unknown 200.2
Periaquaductal grey, dorsal
nTPM: 208.6
1840 Male, age 53, unknown 262.9
1831 Male, age 72, unknown 196.7
2464 Female, age 72, unknown 189.6
2850 Male, age 76, both hemispheres 185.2
Periaquaductal grey, lateral
nTPM: 182.4
2053 Male, age 18, unknown 198.9
2272 Male, age 74, both hemispheres 189.7
2140 Male, age 76, both hemispheres 158.6
Pretectal area
nTPM: 222.3
2273 Male, age 74, both hemispheres 341.0
2224 Female, age 72, unknown 249.0
2407 Male, age 75, both hemispheres 244.1
2667 Female, age 75, unknown 239.5
1815 Male, age 53, unknown 231.9
1816 Male, age 51, unknown 224.8
1944 Female, age 72, unknown 216.6
2825 Male, age 18, unknown 201.5
1817 Female, age 42, unknown 189.8
2007 Male, age 72, unknown 172.4
2316 Male, age 76, right hemisphere 134.8
Red nucleus
nTPM: 139.3
2725 Female, age 75, unknown 188.1
2503 Female, age 72, unknown 185.7
1821 Female, age 72, unknown 170.6
2588 Male, age 74, left hemisphere 145.5
1904 Male, age 53, unknown 137.5
1865 Male, age 51, unknown 133.3
1954 Female, age 42, unknown 133.3
2785 Male, age 18, unknown 130.0
2769 Male, age 72, unknown 126.3
2227 Male, age 72, unknown 123.3
2584 Male, age 75, left hemisphere 108.8
2823 Male, age 76, right hemisphere 89.3
Substantia nigra
nTPM: 217.3
1916 Female, age 42, unknown 303.7
2241 Male, age 72, unknown 292.8
1851 Male, age 51, unknown 265.0
2699 Male, age 18, unknown 214.0
1941 Male, age 53, unknown 213.7
1889 Female, age 72, unknown 204.5
2409 Female, age 72, unknown 204.3
2590 Female, age 75, unknown 162.4
2665 Male, age 74, both hemispheres 157.5
2583 Male, age 75, right hemisphere 155.0
Superior colliculus
nTPM: 200.5
1796 Male, age 53, unknown 234.2
2664 Male, age 75, both hemispheres 228.5
2587 Male, age 74, left hemisphere 216.3
2261 Male, age 18, unknown 205.9
1839 Male, age 51, unknown 205.4
2087 Female, age 72, unknown 205.2
2668 Female, age 75, unknown 199.4
1995 Male, age 72, unknown 193.2
1913 Female, age 42, unknown 171.9
1895 Male, age 76, right hemisphere 144.9
Ventral tegmental area
nTPM: 209.2
1915 Female, age 42, unknown 241.7
2218 Male, age 76, both hemispheres 220.6
2021 Male, age 53, unknown 209.0
2410 Female, age 72, unknown 207.6
1942 Male, age 51, unknown 205.1
2223 Female, age 72, unknown 171.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

63.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 63.5
Samples: 139

Max nTPM: 228.2
Min nTPM: 10.3
Std nTPM: 28.1
Median nTPM: 60.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 228.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 136.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 133.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 127.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 124.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 113.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 112.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 110.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 108.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 107.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 106.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 105.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 100.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 98.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 97.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 95.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 92.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 92.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 86.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 86.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 86.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 86.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 85.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 85.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 84.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 84.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 83.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 81.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 80.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 79.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 79.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 78.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 78.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 76.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 75.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 75.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 74.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 74.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 73.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 73.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 72.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 71.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 71.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 70.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 70.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 70.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 69.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 68.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 67.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 67.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 67.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 66.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 65.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 65.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 65.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 65.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 64.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 64.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 64.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 64.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 63.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 62.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 62.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 62.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 61.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 61.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 60.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 60.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 60.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 60.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 59.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 58.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 58.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 58.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 58.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 57.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 56.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 56.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 55.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 55.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 55.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 54.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 54.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 53.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 52.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 52.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 52.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 52.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 51.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 51.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 51.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 51.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 49.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 49.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 49.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 49.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 49.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 48.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 48.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 48.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 48.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 47.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 46.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 46.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 45.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 45.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 45.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 45.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 44.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 44.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 44.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 44.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 43.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 43.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 43.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 42.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 42.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 39.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 37.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 36.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 35.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 34.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 33.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 33.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 32.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 31.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 31.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 31.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 30.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 29.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 28.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 28.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 26.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 26.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 25.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 21.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 16.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 15.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 10.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

127.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 127.7
FF:10158-103A5 76 years, female 127.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

412.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 349.8
Samples: 4

Max nTPM: 406.8
Min nTPM: 294.3
Sample A Female 406.8
Sample B Female 294.3
Sample C Male 377.6
Sample D Male 320.3
Midbrain
nTPM: 412.7
Samples: 4

Max nTPM: 633.6
Min nTPM: 302.4
Sample A Female 633.6
Sample B Female 323.7
Sample C Male 391.1
Sample D Male 302.4
Periaqueductal gray
nTPM: 386.1
Samples: 3

Max nTPM: 413.6
Min nTPM: 368.4
Sample B Female 376.3
Sample C Male 413.6
Sample D Male 368.4
Superior colliculi
nTPM: 273.0
Samples: 4

Max nTPM: 331.9
Min nTPM: 149.0
Sample A Female 285.9
Sample B Female 149.0
Sample C Male 331.9
Sample D Male 325.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

179.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 179.9
Samples: 4

Max nTPM: 191.0
Min nTPM: 161.6
Sample A Male 161.6
Sample B Male 181.7
Sample C Female 191.0
Sample D Female 185.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.3
416 Antisense, RP_Baylor_102695, Mouse strain C57BL/6J (56 days, male) 2.0
414 Antisense, RP_Baylor_102695, Mouse strain C57BL/6J (56 days, male) 1.5
74300879 Antisense, RP_051219_03_H12, Mouse strain C57BL/6J (56 days, male) 0.5

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