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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
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VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:337.3 nTPM
HPA Brain:735.7 nTPM
GTEx:337.3 nTPM
FANTOM5:536.3 Scaled Tags Per Million
Pig:757.5 nTPM
Mouse:604.3 nTPM
Allen mouse:11.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

735.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 495.6
2586 Male, age 75, left hemisphere 736.9
2828 Female, age 72, unknown 716.0
2666 Male, age 74, left hemisphere 529.6
1827 Male, age 72, unknown 490.5
1833 Male, age 53, unknown 483.9
2411 Female, age 72, unknown 430.8
1870 Female, age 42, unknown 424.7
1830 Male, age 51, unknown 420.1
2219 Male, age 76, both hemispheres 373.3
2019 Male, age 18, unknown 350.3
Dorsal raphe nucleus
nTPM: 600.9
1828 Male, age 53, unknown 743.3
2047 Male, age 72, unknown 695.2
2016 Female, age 72, unknown 611.0
2298 Female, age 72, unknown 516.4
2750 Male, age 76, both hemispheres 438.9
Inferior colliculus
nTPM: 735.7
1848 Female, age 42, unknown 779.8
1890 Male, age 53, unknown 726.5
2849 Male, age 72, unknown 721.6
2097 Female, age 72, unknown 715.0
Median raphe nucleus
nTPM: 394.5
2220 Male, age 76, midline 394.5
Periaquaductal grey, anterior
nTPM: 561.2
2502 Female, age 75, unknown 595.6
1947 Male, age 18, unknown 580.9
1795 Male, age 51, unknown 506.9
Periaquaductal grey, dorsal
nTPM: 577.2
1840 Male, age 53, unknown 651.6
2464 Female, age 72, unknown 627.8
2850 Male, age 76, both hemispheres 585.3
1831 Male, age 72, unknown 444.2
Periaquaductal grey, lateral
nTPM: 498.2
2053 Male, age 18, unknown 608.9
2140 Male, age 76, both hemispheres 598.7
2272 Male, age 74, both hemispheres 287.0
Pretectal area
nTPM: 530.7
1817 Female, age 42, unknown 739.6
2667 Female, age 75, unknown 695.7
1816 Male, age 51, unknown 612.0
2825 Male, age 18, unknown 607.0
1944 Female, age 72, unknown 595.8
1815 Male, age 53, unknown 511.1
2316 Male, age 76, right hemisphere 456.4
2224 Female, age 72, unknown 453.9
2007 Male, age 72, unknown 419.8
2407 Male, age 75, both hemispheres 377.2
2273 Male, age 74, both hemispheres 368.8
Red nucleus
nTPM: 640.6
1821 Female, age 72, unknown 776.2
1954 Female, age 42, unknown 763.9
2503 Female, age 72, unknown 757.0
2588 Male, age 74, left hemisphere 747.5
2823 Male, age 76, right hemisphere 725.6
2227 Male, age 72, unknown 704.8
2769 Male, age 72, unknown 703.0
2725 Female, age 75, unknown 599.0
1865 Male, age 51, unknown 594.7
1904 Male, age 53, unknown 594.1
2584 Male, age 75, left hemisphere 382.7
2785 Male, age 18, unknown 338.7
Substantia nigra
nTPM: 564.3
2699 Male, age 18, unknown 811.9
1916 Female, age 42, unknown 650.3
1889 Female, age 72, unknown 602.7
2665 Male, age 74, both hemispheres 601.1
2241 Male, age 72, unknown 598.7
1851 Male, age 51, unknown 544.1
2409 Female, age 72, unknown 526.7
2583 Male, age 75, right hemisphere 446.3
1941 Male, age 53, unknown 434.5
2590 Female, age 75, unknown 426.8
Superior colliculus
nTPM: 518.8
2664 Male, age 75, both hemispheres 690.3
2087 Female, age 72, unknown 615.2
1839 Male, age 51, unknown 570.6
2261 Male, age 18, unknown 558.5
1796 Male, age 53, unknown 497.2
1995 Male, age 72, unknown 495.6
2668 Female, age 75, unknown 480.9
1895 Male, age 76, right hemisphere 461.2
2587 Male, age 74, left hemisphere 444.4
1913 Female, age 42, unknown 374.2
Ventral tegmental area
nTPM: 471.0
2410 Female, age 72, unknown 559.3
1915 Female, age 42, unknown 480.8
1942 Male, age 51, unknown 477.7
2218 Male, age 76, both hemispheres 455.7
2021 Male, age 53, unknown 455.4
2223 Female, age 72, unknown 397.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

337.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 337.3
Samples: 139

Max nTPM: 1435.9
Min nTPM: 58.9
Std nTPM: 205.8
Median nTPM: 292.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1435.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1164.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 840.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 784.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 765.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 729.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 727.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 672.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 662.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 650.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 627.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 606.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 605.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 592.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 569.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 555.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 553.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 545.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 529.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 521.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 519.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 497.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 491.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 487.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 486.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 485.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 479.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 469.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 465.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 461.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 451.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 448.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 447.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 431.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 427.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 426.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 423.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 420.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 418.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 413.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 412.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 403.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 398.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 398.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 396.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 393.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 393.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 391.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 390.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 386.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 383.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 379.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 376.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 375.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 368.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 367.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 365.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 341.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 338.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 326.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 315.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 313.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 312.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 303.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 300.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 299.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 295.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 294.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 293.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 292.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 291.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 291.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 289.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 288.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 285.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 283.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 282.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 278.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 268.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 265.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 263.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 261.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 261.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 259.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 257.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 253.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 253.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 250.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 250.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 243.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 243.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 235.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 222.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 219.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 212.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 212.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 211.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 202.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 200.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 198.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 193.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 189.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 189.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 182.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 176.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 174.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 170.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 169.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 168.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 167.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 166.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 164.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 164.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 162.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 157.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 155.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 154.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 153.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 147.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 147.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 145.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 142.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 141.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 139.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 138.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 132.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 129.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 128.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 111.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 108.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 105.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 103.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 101.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 97.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 89.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 81.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 75.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 66.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 58.9
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

536.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 536.3
FF:10158-103A5 76 years, female 536.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

757.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 523.2
Samples: 4

Max nTPM: 613.9
Min nTPM: 415.9
Sample A Female 415.9
Sample B Female 595.8
Sample C Male 467.1
Sample D Male 613.9
Midbrain
nTPM: 489.5
Samples: 4

Max nTPM: 606.0
Min nTPM: 300.8
Sample A Female 300.8
Sample B Female 483.6
Sample C Male 606.0
Sample D Male 567.7
Periaqueductal gray
nTPM: 446.4
Samples: 3

Max nTPM: 503.8
Min nTPM: 377.4
Sample B Female 503.8
Sample C Male 458.0
Sample D Male 377.4
Superior colliculi
nTPM: 757.5
Samples: 4

Max nTPM: 1065.2
Min nTPM: 563.5
Sample A Female 803.4
Sample B Female 1065.2
Sample C Male 597.8
Sample D Male 563.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

604.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 604.3
Samples: 4

Max nTPM: 645.7
Min nTPM: 562.0
Sample A Male 582.4
Sample B Male 562.0
Sample C Female 627.1
Sample D Female 645.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

11.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 11.1
69173256 Antisense, RP_050329_01_C04, Mouse strain C57BL/6J (56 days, male) 11.1

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


contact@proteinatlas.org