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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:579.0 nTPM
HPA Brain:520.1 nTPM
GTEx:579.0 nTPM
FANTOM5:2047.9 Scaled Tags Per Million
Pig:319.3 nTPM
Mouse:9.5 nTPM
Allen mouse:0.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

520.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 282.8
2666 Male, age 74, left hemisphere 409.3
1830 Male, age 51, unknown 386.7
2828 Female, age 72, unknown 354.0
1870 Female, age 42, unknown 309.2
1833 Male, age 53, unknown 297.4
2019 Male, age 18, unknown 272.1
2411 Female, age 72, unknown 247.8
1827 Male, age 72, unknown 218.5
2219 Male, age 76, both hemispheres 199.8
2586 Male, age 75, left hemisphere 133.4
Dorsal raphe nucleus
nTPM: 418.8
2016 Female, age 72, unknown 555.9
2298 Female, age 72, unknown 541.2
1828 Male, age 53, unknown 401.1
2750 Male, age 76, both hemispheres 309.7
2047 Male, age 72, unknown 286.0
Inferior colliculus
nTPM: 317.2
2097 Female, age 72, unknown 362.7
2849 Male, age 72, unknown 307.0
1890 Male, age 53, unknown 301.4
1848 Female, age 42, unknown 297.7
Median raphe nucleus
nTPM: 369.0
2220 Male, age 76, midline 369.0
Periaquaductal grey, anterior
nTPM: 284.4
1795 Male, age 51, unknown 358.1
2502 Female, age 75, unknown 265.3
1947 Male, age 18, unknown 229.8
Periaquaductal grey, dorsal
nTPM: 452.6
1831 Male, age 72, unknown 651.4
2850 Male, age 76, both hemispheres 527.0
1840 Male, age 53, unknown 331.7
2464 Female, age 72, unknown 300.5
Periaquaductal grey, lateral
nTPM: 520.1
2272 Male, age 74, both hemispheres 614.9
2140 Male, age 76, both hemispheres 479.9
2053 Male, age 18, unknown 465.5
Pretectal area
nTPM: 330.7
2224 Female, age 72, unknown 477.4
2407 Male, age 75, both hemispheres 448.4
2273 Male, age 74, both hemispheres 445.7
2316 Male, age 76, right hemisphere 431.1
2825 Male, age 18, unknown 305.7
1817 Female, age 42, unknown 290.9
2667 Female, age 75, unknown 289.8
1815 Male, age 53, unknown 284.3
1944 Female, age 72, unknown 275.0
2007 Male, age 72, unknown 259.3
1816 Male, age 51, unknown 130.5
Red nucleus
nTPM: 328.9
1865 Male, age 51, unknown 472.3
2503 Female, age 72, unknown 450.2
2725 Female, age 75, unknown 375.2
2227 Male, age 72, unknown 345.1
2823 Male, age 76, right hemisphere 340.5
2769 Male, age 72, unknown 339.6
1904 Male, age 53, unknown 336.1
2785 Male, age 18, unknown 333.9
1954 Female, age 42, unknown 299.5
1821 Female, age 72, unknown 298.6
2584 Male, age 75, left hemisphere 196.9
2588 Male, age 74, left hemisphere 158.8
Substantia nigra
nTPM: 489.1
2699 Male, age 18, unknown 1018.5
2665 Male, age 74, both hemispheres 663.1
2590 Female, age 75, unknown 630.3
1916 Female, age 42, unknown 449.3
1851 Male, age 51, unknown 423.9
1941 Male, age 53, unknown 413.6
2409 Female, age 72, unknown 380.8
2583 Male, age 75, right hemisphere 370.2
2241 Male, age 72, unknown 317.2
1889 Female, age 72, unknown 223.7
Superior colliculus
nTPM: 363.0
1913 Female, age 42, unknown 676.2
1995 Male, age 72, unknown 571.2
2587 Male, age 74, left hemisphere 520.7
2664 Male, age 75, both hemispheres 344.5
1839 Male, age 51, unknown 327.7
2087 Female, age 72, unknown 293.7
1796 Male, age 53, unknown 287.6
2668 Female, age 75, unknown 226.2
1895 Male, age 76, right hemisphere 193.4
2261 Male, age 18, unknown 188.9
Ventral tegmental area
nTPM: 483.7
2021 Male, age 53, unknown 754.9
1915 Female, age 42, unknown 488.0
2218 Male, age 76, both hemispheres 460.4
1942 Male, age 51, unknown 439.1
2410 Female, age 72, unknown 394.6
2223 Female, age 72, unknown 365.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

579.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 579.0
Samples: 139

Max nTPM: 2332.4
Min nTPM: 80.2
Std nTPM: 421.3
Median nTPM: 482.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 2332.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 2062.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 2009.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1730.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1539.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1485.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1482.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1379.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1299.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1277.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1273.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1255.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1222.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1152.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1146.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1139.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1130.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1100.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1025.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 1000.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 996.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 991.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 978.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 941.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 922.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 896.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 889.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 837.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 817.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 797.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 772.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 756.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 754.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 748.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 745.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 738.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 721.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 721.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 701.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 692.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 681.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 672.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 669.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 661.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 636.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 636.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 633.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 617.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 603.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 600.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 575.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 575.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 563.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 559.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 549.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 547.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 546.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 543.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 528.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 521.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 513.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 512.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 504.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 503.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 502.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 491.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 490.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 486.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 483.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 482.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 479.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 462.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 461.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 458.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 443.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 433.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 426.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 425.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 399.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 393.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 392.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 385.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 383.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 381.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 381.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 369.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 357.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 347.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 346.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 343.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 341.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 339.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 339.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 337.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 335.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 332.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 320.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 318.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 315.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 313.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 303.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 292.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 281.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 279.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 274.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 267.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 267.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 262.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 260.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 258.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 256.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 246.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 240.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 236.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 214.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 214.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 212.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 210.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 208.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 206.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 202.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 195.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 193.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 183.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 179.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 173.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 158.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 154.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 142.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 139.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 138.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 133.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 133.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 128.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 118.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 106.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 104.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 100.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 80.2
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

2047.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 2047.9
FF:10158-103A5 76 years, female 2047.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

319.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 319.3
Samples: 4

Max nTPM: 480.6
Min nTPM: 192.1
Sample A Female 268.6
Sample B Female 480.6
Sample C Male 192.1
Sample D Male 335.9
Midbrain
nTPM: 223.5
Samples: 4

Max nTPM: 445.9
Min nTPM: 105.8
Sample A Female 445.9
Sample B Female 203.0
Sample C Male 139.1
Sample D Male 105.8
Periaqueductal gray
nTPM: 190.7
Samples: 3

Max nTPM: 244.9
Min nTPM: 144.6
Sample B Female 182.5
Sample C Male 244.9
Sample D Male 144.6
Superior colliculi
nTPM: 232.4
Samples: 4

Max nTPM: 248.1
Min nTPM: 202.4
Sample A Female 248.1
Sample B Female 235.8
Sample C Male 202.4
Sample D Male 243.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

9.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 9.5
Samples: 4

Max nTPM: 15.6
Min nTPM: 4.8
Sample A Male 15.6
Sample B Male 10.5
Sample C Female 4.8
Sample D Female 6.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.5
67979029 Antisense, RP_040923_02_A10, Mouse strain C57BL/6J (56 days, male) 0.5

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