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PLEKHB1
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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:1765.6 nTPM
HPA Brain:1403.6 nTPM
GTEx:1765.6 nTPM
FANTOM5:1607.2 Scaled Tags Per Million
Pig:885.6 nTPM
Mouse:697.2 nTPM
Allen mouse:4.2 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1403.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 1116.7
2828 Female, age 72, unknown 1309.4
1870 Female, age 42, unknown 1301.8
1830 Male, age 51, unknown 1239.6
1833 Male, age 53, unknown 1221.2
2411 Female, age 72, unknown 1145.2
2666 Male, age 74, left hemisphere 1132.3
2586 Male, age 75, left hemisphere 1041.1
2019 Male, age 18, unknown 1040.7
1827 Male, age 72, unknown 928.9
2219 Male, age 76, both hemispheres 806.5
Dorsal raphe nucleus
nTPM: 1036.0
2750 Male, age 76, both hemispheres 1395.2
2016 Female, age 72, unknown 1151.1
1828 Male, age 53, unknown 981.4
2047 Male, age 72, unknown 869.8
2298 Female, age 72, unknown 782.6
Inferior colliculus
nTPM: 846.5
2849 Male, age 72, unknown 924.7
1890 Male, age 53, unknown 885.7
1848 Female, age 42, unknown 852.5
2097 Female, age 72, unknown 723.1
Median raphe nucleus
nTPM: 1018.1
2220 Male, age 76, midline 1018.1
Periaquaductal grey, anterior
nTPM: 786.4
2502 Female, age 75, unknown 834.1
1795 Male, age 51, unknown 791.3
1947 Male, age 18, unknown 733.9
Periaquaductal grey, dorsal
nTPM: 855.9
2464 Female, age 72, unknown 952.8
2850 Male, age 76, both hemispheres 884.8
1831 Male, age 72, unknown 848.7
1840 Male, age 53, unknown 737.3
Periaquaductal grey, lateral
nTPM: 846.9
2053 Male, age 18, unknown 1003.3
2140 Male, age 76, both hemispheres 807.3
2272 Male, age 74, both hemispheres 730.2
Pretectal area
nTPM: 816.8
2316 Male, age 76, right hemisphere 1034.7
1815 Male, age 53, unknown 1026.6
2825 Male, age 18, unknown 966.4
1817 Female, age 42, unknown 821.3
2667 Female, age 75, unknown 798.5
2407 Male, age 75, both hemispheres 780.5
2224 Female, age 72, unknown 778.1
2273 Male, age 74, both hemispheres 760.3
1944 Female, age 72, unknown 712.2
2007 Male, age 72, unknown 689.2
1816 Male, age 51, unknown 616.9
Red nucleus
nTPM: 1403.6
2503 Female, age 72, unknown 1682.4
2769 Male, age 72, unknown 1581.3
2227 Male, age 72, unknown 1558.9
2823 Male, age 76, right hemisphere 1539.8
1904 Male, age 53, unknown 1532.6
1865 Male, age 51, unknown 1475.7
1821 Female, age 72, unknown 1453.8
2588 Male, age 74, left hemisphere 1406.6
1954 Female, age 42, unknown 1268.0
2785 Male, age 18, unknown 1213.4
2584 Male, age 75, left hemisphere 1081.3
2725 Female, age 75, unknown 1049.8
Substantia nigra
nTPM: 1014.6
2699 Male, age 18, unknown 1301.2
2665 Male, age 74, both hemispheres 1125.5
2590 Female, age 75, unknown 1122.2
1851 Male, age 51, unknown 1117.3
2583 Male, age 75, right hemisphere 993.1
1916 Female, age 42, unknown 946.9
2409 Female, age 72, unknown 941.6
1889 Female, age 72, unknown 918.9
1941 Male, age 53, unknown 840.3
2241 Male, age 72, unknown 839.2
Superior colliculus
nTPM: 995.1
1913 Female, age 42, unknown 1439.8
1995 Male, age 72, unknown 1348.3
2668 Female, age 75, unknown 1091.2
2587 Male, age 74, left hemisphere 1077.2
1839 Male, age 51, unknown 1008.6
1895 Male, age 76, right hemisphere 896.0
1796 Male, age 53, unknown 870.2
2664 Male, age 75, both hemispheres 816.8
2087 Female, age 72, unknown 724.0
2261 Male, age 18, unknown 679.2
Ventral tegmental area
nTPM: 1103.8
2223 Female, age 72, unknown 1368.1
2410 Female, age 72, unknown 1192.4
2021 Male, age 53, unknown 1068.0
1942 Male, age 51, unknown 1030.1
1915 Female, age 42, unknown 990.7
2218 Male, age 76, both hemispheres 973.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1765.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1765.6
Samples: 139

Max nTPM: 4097.1
Min nTPM: 427.3
Std nTPM: 720.3
Median nTPM: 1569.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 4097.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 3896.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 3389.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 3330.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 3308.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 3223.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 3206.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 3130.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 3123.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 3073.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 3038.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 2982.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 2975.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 2959.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 2856.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 2806.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 2787.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 2675.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 2663.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 2623.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 2577.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 2573.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 2523.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 2489.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 2444.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 2430.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 2377.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 2341.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 2337.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 2289.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 2257.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 2234.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 2225.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 2217.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 2154.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 2145.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 2081.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 2080.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 2073.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 2062.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 2047.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 2034.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 2023.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1998.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1984.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1983.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1939.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1931.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1913.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1911.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1901.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1882.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1845.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1809.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1803.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 1798.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1797.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1778.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1772.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1713.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1708.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1704.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 1701.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1669.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1636.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1633.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 1578.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 1578.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1570.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1569.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 1561.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 1548.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1546.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1535.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1522.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1521.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1511.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1511.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1510.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1482.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1476.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1476.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 1471.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1468.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1456.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 1447.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1433.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1416.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1416.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1409.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 1396.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1376.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1366.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1353.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1334.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 1308.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1304.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1303.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1286.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 1280.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1272.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1266.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1250.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1245.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1245.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1243.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1193.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1192.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1189.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 1187.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 1181.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1156.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1152.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1152.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1145.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1114.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1110.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 1107.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1096.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1095.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1085.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 1080.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1051.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1043.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1041.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 1036.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 1025.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 996.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 966.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 942.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 911.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 864.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 837.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 756.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 746.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 610.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 569.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 512.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 427.3
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1607.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1607.2
FF:10158-103A5 76 years, female 1607.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

885.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 820.7
Samples: 4

Max nTPM: 1130.8
Min nTPM: 572.2
Sample A Female 819.8
Sample B Female 572.2
Sample C Male 760.1
Sample D Male 1130.8
Midbrain
nTPM: 885.6
Samples: 4

Max nTPM: 1638.5
Min nTPM: 466.8
Sample A Female 1638.5
Sample B Female 966.9
Sample C Male 470.3
Sample D Male 466.8
Periaqueductal gray
nTPM: 789.3
Samples: 3

Max nTPM: 820.8
Min nTPM: 769.6
Sample B Female 820.8
Sample C Male 777.6
Sample D Male 769.6
Superior colliculi
nTPM: 645.5
Samples: 4

Max nTPM: 775.2
Min nTPM: 413.9
Sample A Female 699.2
Sample B Female 413.9
Sample C Male 693.8
Sample D Male 775.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

697.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 697.2
Samples: 4

Max nTPM: 761.2
Min nTPM: 658.4
Sample A Male 761.2
Sample B Male 658.4
Sample C Female 660.8
Sample D Female 708.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.2
71836842 Antisense, RP_051017_02_C05, Mouse strain C57BL/6J (56 days, male) 7.2
68196931 Antisense, RP_041116_01_F10, Mouse strain C57BL/6J (56 days, male) 1.3

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