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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:107.1 nTPM
HPA Brain:150.8 nTPM
GTEx:107.1 nTPM
FANTOM5:31.1 Scaled Tags Per Million
Pig:116.9 nTPM
Mouse:99.8 nTPM
Allen mouse:4.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

150.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 94.5
2586 Male, age 75, left hemisphere 118.7
1827 Male, age 72, unknown 110.9
2828 Female, age 72, unknown 106.8
2019 Male, age 18, unknown 97.1
2666 Male, age 74, left hemisphere 96.1
2219 Male, age 76, both hemispheres 91.8
2411 Female, age 72, unknown 84.4
1870 Female, age 42, unknown 83.9
1833 Male, age 53, unknown 80.1
1830 Male, age 51, unknown 75.4
Dorsal raphe nucleus
nTPM: 134.3
2298 Female, age 72, unknown 194.4
2047 Male, age 72, unknown 138.9
2016 Female, age 72, unknown 138.6
1828 Male, age 53, unknown 105.5
2750 Male, age 76, both hemispheres 94.4
Inferior colliculus
nTPM: 105.1
2097 Female, age 72, unknown 117.1
1848 Female, age 42, unknown 102.8
1890 Male, age 53, unknown 101.9
2849 Male, age 72, unknown 98.5
Median raphe nucleus
nTPM: 114.2
2220 Male, age 76, midline 114.2
Periaquaductal grey, anterior
nTPM: 135.3
1795 Male, age 51, unknown 151.1
2502 Female, age 75, unknown 145.5
1947 Male, age 18, unknown 109.5
Periaquaductal grey, dorsal
nTPM: 140.5
1840 Male, age 53, unknown 179.0
2850 Male, age 76, both hemispheres 152.6
2464 Female, age 72, unknown 119.5
1831 Male, age 72, unknown 110.9
Periaquaductal grey, lateral
nTPM: 150.8
2272 Male, age 74, both hemispheres 165.2
2140 Male, age 76, both hemispheres 153.6
2053 Male, age 18, unknown 133.7
Pretectal area
nTPM: 134.5
2273 Male, age 74, both hemispheres 198.9
2224 Female, age 72, unknown 155.5
1816 Male, age 51, unknown 148.6
1944 Female, age 72, unknown 135.3
1817 Female, age 42, unknown 133.3
1815 Male, age 53, unknown 133.2
2007 Male, age 72, unknown 128.8
2407 Male, age 75, both hemispheres 121.8
2667 Female, age 75, unknown 117.8
2825 Male, age 18, unknown 107.0
2316 Male, age 76, right hemisphere 98.9
Red nucleus
nTPM: 77.3
2785 Male, age 18, unknown 106.0
2725 Female, age 75, unknown 87.1
1821 Female, age 72, unknown 79.9
1904 Male, age 53, unknown 78.8
2584 Male, age 75, left hemisphere 78.2
2769 Male, age 72, unknown 78.0
2227 Male, age 72, unknown 77.5
2503 Female, age 72, unknown 77.4
1954 Female, age 42, unknown 74.4
1865 Male, age 51, unknown 69.1
2823 Male, age 76, right hemisphere 61.6
2588 Male, age 74, left hemisphere 59.8
Substantia nigra
nTPM: 120.5
1916 Female, age 42, unknown 151.6
1851 Male, age 51, unknown 137.4
2241 Male, age 72, unknown 131.3
2699 Male, age 18, unknown 127.6
2590 Female, age 75, unknown 120.8
1889 Female, age 72, unknown 112.1
1941 Male, age 53, unknown 108.2
2583 Male, age 75, right hemisphere 108.2
2665 Male, age 74, both hemispheres 107.7
2409 Female, age 72, unknown 100.2
Superior colliculus
nTPM: 115.3
2664 Male, age 75, both hemispheres 164.4
1796 Male, age 53, unknown 130.0
2087 Female, age 72, unknown 128.6
2261 Male, age 18, unknown 125.6
2587 Male, age 74, left hemisphere 118.2
1995 Male, age 72, unknown 107.5
1839 Male, age 51, unknown 105.6
2668 Female, age 75, unknown 101.9
1913 Female, age 42, unknown 89.4
1895 Male, age 76, right hemisphere 82.4
Ventral tegmental area
nTPM: 114.6
2410 Female, age 72, unknown 127.0
1915 Female, age 42, unknown 125.1
2021 Male, age 53, unknown 120.7
1942 Male, age 51, unknown 115.3
2218 Male, age 76, both hemispheres 107.8
2223 Female, age 72, unknown 91.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

107.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 107.1
Samples: 139

Max nTPM: 242.9
Min nTPM: 21.6
Std nTPM: 34.5
Median nTPM: 103.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 242.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 213.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 212.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 190.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 189.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 165.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 164.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 162.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 160.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 158.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 157.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 156.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 151.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 150.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 150.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 149.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 148.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 147.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 147.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 146.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 146.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 141.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 139.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 137.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 134.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 131.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 129.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 128.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 126.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 126.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 125.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 123.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 123.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 120.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 119.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 118.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 118.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 117.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 117.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 117.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 116.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 116.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 114.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 113.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 113.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 113.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 112.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 112.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 112.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 112.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 111.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 111.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 111.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 111.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 111.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 111.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 110.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 109.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 108.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 108.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 107.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 106.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 106.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 106.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 105.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 104.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 104.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 103.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 103.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 103.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 103.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 102.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 102.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 101.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 101.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 101.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 101.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 100.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 100.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 100.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 100.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 100.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 99.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 99.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 99.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 99.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 97.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 96.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 96.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 96.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 96.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 96.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 95.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 93.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 92.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 92.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 92.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 90.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 90.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 90.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 90.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 90.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 90.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 89.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 88.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 86.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 84.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 84.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 83.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 82.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 82.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 82.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 81.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 81.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 81.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 80.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 79.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 79.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 78.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 75.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 74.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 74.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 73.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 72.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 72.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 70.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 67.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 63.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 57.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 57.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 54.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 49.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 49.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 48.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 47.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 44.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 41.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 37.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 21.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

31.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 31.1
FF:10158-103A5 76 years, female 31.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

116.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 67.1
Samples: 4

Max nTPM: 81.7
Min nTPM: 38.2
Sample A Female 77.6
Sample B Female 81.7
Sample C Male 70.8
Sample D Male 38.2
Midbrain
nTPM: 62.8
Samples: 4

Max nTPM: 66.7
Min nTPM: 59.3
Sample A Female 63.5
Sample B Female 66.7
Sample C Male 61.7
Sample D Male 59.3
Periaqueductal gray
nTPM: 116.9
Samples: 3

Max nTPM: 149.2
Min nTPM: 90.9
Sample B Female 90.9
Sample C Male 149.2
Sample D Male 110.5
Superior colliculi
nTPM: 51.0
Samples: 4

Max nTPM: 61.8
Min nTPM: 38.5
Sample A Female 61.8
Sample B Female 45.3
Sample C Male 38.5
Sample D Male 58.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

99.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 99.8
Samples: 4

Max nTPM: 101.6
Min nTPM: 98.3
Sample A Male 100.4
Sample B Male 101.6
Sample C Female 98.3
Sample D Female 99.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.5
2219 Antisense, RP_040604_01_A03, Mouse strain C57BL/6J (56 days, male) 4.5
2218 Antisense, RP_040604_01_A03, Mouse strain C57BL/6J (56 days, male) 1.4

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