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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:570.6 nTPM
HPA Brain:718.6 nTPM
GTEx:570.6 nTPM
FANTOM5:575.4 Scaled Tags Per Million
Pig:273.5 nTPM
Mouse:372.3 nTPM
Allen mouse:6.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

718.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 679.9
2666 Male, age 74, left hemisphere 904.8
2586 Male, age 75, left hemisphere 895.7
2019 Male, age 18, unknown 854.7
2828 Female, age 72, unknown 691.4
1827 Male, age 72, unknown 655.7
1833 Male, age 53, unknown 608.6
1830 Male, age 51, unknown 595.6
2411 Female, age 72, unknown 589.4
1870 Female, age 42, unknown 543.2
2219 Male, age 76, both hemispheres 460.2
Dorsal raphe nucleus
nTPM: 523.8
2750 Male, age 76, both hemispheres 619.8
1828 Male, age 53, unknown 544.7
2016 Female, age 72, unknown 519.6
2047 Male, age 72, unknown 489.8
2298 Female, age 72, unknown 445.1
Inferior colliculus
nTPM: 465.5
1890 Male, age 53, unknown 518.4
1848 Female, age 42, unknown 473.4
2849 Male, age 72, unknown 465.8
2097 Female, age 72, unknown 404.6
Median raphe nucleus
nTPM: 566.1
2220 Male, age 76, midline 566.1
Periaquaductal grey, anterior
nTPM: 557.1
2502 Female, age 75, unknown 616.1
1795 Male, age 51, unknown 547.8
1947 Male, age 18, unknown 507.4
Periaquaductal grey, dorsal
nTPM: 487.2
2850 Male, age 76, both hemispheres 540.6
1831 Male, age 72, unknown 512.8
2464 Female, age 72, unknown 499.2
1840 Male, age 53, unknown 396.1
Periaquaductal grey, lateral
nTPM: 477.4
2140 Male, age 76, both hemispheres 499.3
2053 Male, age 18, unknown 483.7
2272 Male, age 74, both hemispheres 449.2
Pretectal area
nTPM: 637.7
2007 Male, age 72, unknown 886.2
1816 Male, age 51, unknown 858.5
1815 Male, age 53, unknown 855.7
1817 Female, age 42, unknown 783.1
1944 Female, age 72, unknown 774.2
2407 Male, age 75, both hemispheres 577.5
2316 Male, age 76, right hemisphere 495.8
2825 Male, age 18, unknown 475.6
2667 Female, age 75, unknown 467.9
2224 Female, age 72, unknown 427.1
2273 Male, age 74, both hemispheres 412.8
Red nucleus
nTPM: 718.6
2588 Male, age 74, left hemisphere 998.0
2785 Male, age 18, unknown 836.8
2503 Female, age 72, unknown 795.9
2584 Male, age 75, left hemisphere 752.1
1865 Male, age 51, unknown 712.2
1904 Male, age 53, unknown 707.5
2725 Female, age 75, unknown 697.4
1821 Female, age 72, unknown 665.6
2823 Male, age 76, right hemisphere 626.1
1954 Female, age 42, unknown 613.8
2769 Male, age 72, unknown 610.7
2227 Male, age 72, unknown 607.4
Substantia nigra
nTPM: 637.2
2665 Male, age 74, both hemispheres 762.9
1889 Female, age 72, unknown 699.7
2583 Male, age 75, right hemisphere 671.8
1916 Female, age 42, unknown 667.6
2590 Female, age 75, unknown 655.0
1851 Male, age 51, unknown 640.7
2241 Male, age 72, unknown 589.1
1941 Male, age 53, unknown 578.4
2699 Male, age 18, unknown 559.8
2409 Female, age 72, unknown 547.2
Superior colliculus
nTPM: 627.5
2668 Female, age 75, unknown 723.4
2664 Male, age 75, both hemispheres 693.0
2587 Male, age 74, left hemisphere 681.2
2087 Female, age 72, unknown 670.2
2261 Male, age 18, unknown 645.9
1995 Male, age 72, unknown 637.3
1913 Female, age 42, unknown 618.5
1796 Male, age 53, unknown 595.0
1839 Male, age 51, unknown 548.9
1895 Male, age 76, right hemisphere 461.7
Ventral tegmental area
nTPM: 561.2
2410 Female, age 72, unknown 627.8
2223 Female, age 72, unknown 593.8
2218 Male, age 76, both hemispheres 577.9
1915 Female, age 42, unknown 537.6
2021 Male, age 53, unknown 525.3
1942 Male, age 51, unknown 504.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

570.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 570.6
Samples: 139

Max nTPM: 1335.8
Min nTPM: 227.5
Std nTPM: 246.5
Median nTPM: 497.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1335.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1264.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1226.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1186.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1147.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1134.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1127.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1106.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1091.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1068.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1023.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1006.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 993.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 954.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 941.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 934.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 926.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 913.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 893.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 880.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 875.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 851.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 831.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 819.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 809.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 804.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 757.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 751.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 743.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 732.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 717.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 705.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 686.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 684.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 684.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 677.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 676.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 661.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 652.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 648.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 643.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 631.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 629.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 626.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 621.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 618.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 614.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 614.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 613.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 605.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 573.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 573.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 564.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 555.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 545.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 543.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 534.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 530.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 529.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 528.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 521.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 516.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 514.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 511.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 509.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 508.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 507.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 505.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 501.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 497.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 495.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 491.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 483.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 478.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 476.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 475.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 472.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 468.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 466.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 462.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 461.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 458.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 450.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 450.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 438.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 435.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 434.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 429.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 428.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 427.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 425.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 420.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 415.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 412.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 409.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 405.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 403.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 401.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 399.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 396.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 393.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 393.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 392.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 389.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 386.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 383.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 382.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 382.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 381.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 375.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 373.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 369.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 369.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 368.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 365.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 363.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 362.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 362.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 356.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 355.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 355.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 351.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 347.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 346.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 325.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 319.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 316.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 316.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 307.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 303.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 302.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 300.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 300.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 296.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 290.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 285.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 263.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 248.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 227.5
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

575.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 575.4
FF:10158-103A5 76 years, female 575.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

273.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 169.0
Samples: 4

Max nTPM: 190.0
Min nTPM: 154.1
Sample A Female 172.9
Sample B Female 154.1
Sample C Male 158.8
Sample D Male 190.0
Midbrain
nTPM: 273.6
Samples: 4

Max nTPM: 469.2
Min nTPM: 140.6
Sample A Female 308.5
Sample B Female 140.6
Sample C Male 469.2
Sample D Male 175.9
Periaqueductal gray
nTPM: 134.6
Samples: 3

Max nTPM: 140.7
Min nTPM: 128.5
Sample B Female 134.6
Sample C Male 140.7
Sample D Male 128.5
Superior colliculi
nTPM: 254.2
Samples: 4

Max nTPM: 375.9
Min nTPM: 183.7
Sample A Female 214.4
Sample B Female 183.7
Sample C Male 375.9
Sample D Male 242.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

372.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 372.3
Samples: 4

Max nTPM: 377.5
Min nTPM: 368.8
Sample A Male 372.3
Sample B Male 377.5
Sample C Female 370.6
Sample D Female 368.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

6.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.5
68845598 Antisense, RP_050224_02_B05, Mouse strain C57BL/6J (56 days, male) 6.5
71587919 Antisense, RP_050725_03_G05, Mouse strain C57BL/6J (56 days, male) 6.5

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The Human Protein Atlas

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


contact@proteinatlas.org