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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
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VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:73.5 nTPM
HPA Brain:260.6 nTPM
GTEx:73.5 nTPM
FANTOM5:3.8 Scaled Tags Per Million
Pig:226.1 nTPM
Mouse:232.5 nTPM
Allen mouse:9.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

260.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 143.4
2219 Male, age 76, both hemispheres 300.4
1827 Male, age 72, unknown 219.0
2828 Female, age 72, unknown 184.4
2019 Male, age 18, unknown 183.7
2411 Female, age 72, unknown 113.9
2666 Male, age 74, left hemisphere 100.3
1833 Male, age 53, unknown 97.4
1870 Female, age 42, unknown 96.4
1830 Male, age 51, unknown 82.3
2586 Male, age 75, left hemisphere 56.4
Dorsal raphe nucleus
nTPM: 119.6
2298 Female, age 72, unknown 215.6
2750 Male, age 76, both hemispheres 174.7
2047 Male, age 72, unknown 109.2
2016 Female, age 72, unknown 52.4
1828 Male, age 53, unknown 46.1
Inferior colliculus
nTPM: 109.6
2097 Female, age 72, unknown 153.8
1848 Female, age 42, unknown 113.3
1890 Male, age 53, unknown 90.9
2849 Male, age 72, unknown 80.3
Median raphe nucleus
nTPM: 234.6
2220 Male, age 76, midline 234.6
Periaquaductal grey, anterior
nTPM: 167.3
2502 Female, age 75, unknown 196.6
1795 Male, age 51, unknown 163.2
1947 Male, age 18, unknown 142.1
Periaquaductal grey, dorsal
nTPM: 112.5
1831 Male, age 72, unknown 136.2
2850 Male, age 76, both hemispheres 113.6
1840 Male, age 53, unknown 108.5
2464 Female, age 72, unknown 91.5
Periaquaductal grey, lateral
nTPM: 87.0
2053 Male, age 18, unknown 100.0
2140 Male, age 76, both hemispheres 88.0
2272 Male, age 74, both hemispheres 72.8
Pretectal area
nTPM: 228.9
1816 Male, age 51, unknown 452.7
1944 Female, age 72, unknown 381.2
1815 Male, age 53, unknown 340.3
1817 Female, age 42, unknown 333.6
2007 Male, age 72, unknown 271.2
2667 Female, age 75, unknown 229.2
2224 Female, age 72, unknown 137.2
2316 Male, age 76, right hemisphere 115.3
2407 Male, age 75, both hemispheres 96.8
2825 Male, age 18, unknown 87.9
2273 Male, age 74, both hemispheres 72.7
Red nucleus
nTPM: 109.3
2785 Male, age 18, unknown 168.4
2503 Female, age 72, unknown 129.3
1904 Male, age 53, unknown 126.6
1821 Female, age 72, unknown 124.8
1954 Female, age 42, unknown 123.4
2823 Male, age 76, right hemisphere 114.6
2584 Male, age 75, left hemisphere 108.5
2725 Female, age 75, unknown 100.3
1865 Male, age 51, unknown 98.6
2227 Male, age 72, unknown 76.9
2769 Male, age 72, unknown 72.0
2588 Male, age 74, left hemisphere 68.1
Substantia nigra
nTPM: 260.6
1916 Female, age 42, unknown 406.7
1941 Male, age 53, unknown 382.8
2665 Male, age 74, both hemispheres 357.9
1889 Female, age 72, unknown 312.5
2409 Female, age 72, unknown 281.1
1851 Male, age 51, unknown 270.9
2241 Male, age 72, unknown 238.1
2699 Male, age 18, unknown 174.2
2590 Female, age 75, unknown 101.5
2583 Male, age 75, right hemisphere 80.1
Superior colliculus
nTPM: 180.0
2087 Female, age 72, unknown 369.0
1796 Male, age 53, unknown 276.4
2668 Female, age 75, unknown 267.4
2261 Male, age 18, unknown 200.6
1913 Female, age 42, unknown 151.5
1895 Male, age 76, right hemisphere 148.2
1995 Male, age 72, unknown 125.6
1839 Male, age 51, unknown 108.4
2587 Male, age 74, left hemisphere 77.5
2664 Male, age 75, both hemispheres 75.9
Ventral tegmental area
nTPM: 231.1
2218 Male, age 76, both hemispheres 410.6
2410 Female, age 72, unknown 311.4
1915 Female, age 42, unknown 234.5
1942 Male, age 51, unknown 184.7
2223 Female, age 72, unknown 130.8
2021 Male, age 53, unknown 114.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

73.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 73.5
Samples: 139

Max nTPM: 389.7
Min nTPM: 0.5
Std nTPM: 77.8
Median nTPM: 46.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 389.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 376.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 339.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 329.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 247.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 228.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 216.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 211.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 202.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 198.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 195.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 190.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 187.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 185.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 173.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 173.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 170.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 163.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 158.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 150.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 146.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 144.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 140.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 139.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 130.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 127.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 126.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 125.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 116.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 116.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 111.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 111.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 108.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 105.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 104.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 103.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 100.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 98.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 96.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 94.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 93.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 92.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 90.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 90.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 89.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 89.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 89.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 88.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 88.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 85.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 84.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 84.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 82.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 78.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 76.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 74.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 71.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 71.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 70.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 68.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 62.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 61.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 61.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 59.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 57.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 53.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 53.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 50.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 47.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 46.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 44.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 44.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 42.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 41.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 41.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 41.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 41.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 38.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 36.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 34.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 34.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 31.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 29.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 27.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 25.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 24.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 23.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 23.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 23.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 22.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 21.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 21.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 20.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 19.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 19.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 19.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 18.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 17.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 17.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 16.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 15.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 15.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 14.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 14.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 12.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 12.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 11.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 11.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 11.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 11.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 11.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 11.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 10.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 10.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 10.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 9.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 9.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 8.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 7.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 6.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 6.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 5.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 5.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 4.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 4.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 4.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 4.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 4.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 4.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 3.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 3.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 3.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 3.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 2.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 2.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 0.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 0.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 0.5
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

3.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 3.8
FF:10158-103A5 76 years, female 3.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

226.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 205.5
Samples: 4

Max nTPM: 370.3
Min nTPM: 27.2
Sample A Female 272.5
Sample B Female 151.8
Sample C Male 370.3
Sample D Male 27.2
Midbrain
nTPM: 226.1
Samples: 4

Max nTPM: 480.4
Min nTPM: 48.0
Sample A Female 48.0
Sample B Female 116.4
Sample C Male 480.4
Sample D Male 259.5
Periaqueductal gray
nTPM: 93.3
Samples: 3

Max nTPM: 149.2
Min nTPM: 63.9
Sample B Female 66.8
Sample C Male 149.2
Sample D Male 63.9
Superior colliculi
nTPM: 220.6
Samples: 4

Max nTPM: 397.1
Min nTPM: 115.1
Sample A Female 115.1
Sample B Female 115.7
Sample C Male 397.1
Sample D Male 254.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

232.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 232.5
Samples: 4

Max nTPM: 258.8
Min nTPM: 207.1
Sample A Male 207.1
Sample B Male 232.4
Sample C Female 258.8
Sample D Female 231.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.8
1015 Antisense, RP_Baylor_103052, Mouse strain C57BL/6J (56 days, male) 19.6
1014 Antisense, RP_Baylor_103052, Mouse strain C57BL/6J (56 days, male) 18.8
1016 Sense, RPS_Baylor_37049, Mouse strain C57BL/6J (56 days, male) 0.0

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by the Knut & Alice Wallenberg Foundation.


contact@proteinatlas.org