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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:135.6 nTPM
HPA Brain:384.0 nTPM
GTEx:135.6 nTPM
FANTOM5:308.7 Scaled Tags Per Million
Pig:179.6 nTPM
Mouse:68.2 nTPM
Allen mouse:7.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

384.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 320.6
2666 Male, age 74, left hemisphere 415.8
1833 Male, age 53, unknown 375.1
1830 Male, age 51, unknown 370.9
2586 Male, age 75, left hemisphere 369.4
1870 Female, age 42, unknown 313.4
2411 Female, age 72, unknown 305.2
2828 Female, age 72, unknown 298.5
2019 Male, age 18, unknown 281.7
2219 Male, age 76, both hemispheres 241.9
1827 Male, age 72, unknown 234.4
Dorsal raphe nucleus
nTPM: 218.7
2750 Male, age 76, both hemispheres 317.7
2016 Female, age 72, unknown 258.4
1828 Male, age 53, unknown 225.2
2047 Male, age 72, unknown 166.7
2298 Female, age 72, unknown 125.5
Inferior colliculus
nTPM: 216.1
2849 Male, age 72, unknown 257.4
1848 Female, age 42, unknown 236.0
1890 Male, age 53, unknown 218.6
2097 Female, age 72, unknown 152.4
Median raphe nucleus
nTPM: 216.6
2220 Male, age 76, midline 216.6
Periaquaductal grey, anterior
nTPM: 213.0
2502 Female, age 75, unknown 235.1
1947 Male, age 18, unknown 220.9
1795 Male, age 51, unknown 183.0
Periaquaductal grey, dorsal
nTPM: 184.9
2464 Female, age 72, unknown 234.0
1831 Male, age 72, unknown 196.2
2850 Male, age 76, both hemispheres 170.3
1840 Male, age 53, unknown 139.2
Periaquaductal grey, lateral
nTPM: 187.9
2053 Male, age 18, unknown 209.9
2140 Male, age 76, both hemispheres 177.0
2272 Male, age 74, both hemispheres 176.8
Pretectal area
nTPM: 206.0
1815 Male, age 53, unknown 289.0
2407 Male, age 75, both hemispheres 280.7
2316 Male, age 76, right hemisphere 274.3
1817 Female, age 42, unknown 233.0
2825 Male, age 18, unknown 232.3
2007 Male, age 72, unknown 201.3
2224 Female, age 72, unknown 166.5
2273 Male, age 74, both hemispheres 150.5
1944 Female, age 72, unknown 148.5
1816 Male, age 51, unknown 145.5
2667 Female, age 75, unknown 144.2
Red nucleus
nTPM: 384.0
2503 Female, age 72, unknown 466.8
1865 Male, age 51, unknown 458.0
1904 Male, age 53, unknown 408.1
2588 Male, age 74, left hemisphere 396.4
2227 Male, age 72, unknown 395.3
2769 Male, age 72, unknown 390.6
2823 Male, age 76, right hemisphere 387.6
1821 Female, age 72, unknown 358.1
2725 Female, age 75, unknown 356.0
2785 Male, age 18, unknown 355.4
1954 Female, age 42, unknown 350.9
2584 Male, age 75, left hemisphere 284.9
Substantia nigra
nTPM: 231.8
2699 Male, age 18, unknown 295.0
2409 Female, age 72, unknown 256.7
2665 Male, age 74, both hemispheres 253.4
2590 Female, age 75, unknown 250.2
1851 Male, age 51, unknown 245.5
2583 Male, age 75, right hemisphere 232.2
1889 Female, age 72, unknown 228.2
1941 Male, age 53, unknown 198.0
2241 Male, age 72, unknown 186.2
1916 Female, age 42, unknown 172.1
Superior colliculus
nTPM: 277.4
1995 Male, age 72, unknown 390.8
1913 Female, age 42, unknown 383.5
2668 Female, age 75, unknown 325.4
2587 Male, age 74, left hemisphere 297.7
1839 Male, age 51, unknown 285.1
1895 Male, age 76, right hemisphere 275.2
2664 Male, age 75, both hemispheres 250.6
1796 Male, age 53, unknown 212.9
2261 Male, age 18, unknown 182.6
2087 Female, age 72, unknown 170.7
Ventral tegmental area
nTPM: 240.0
2223 Female, age 72, unknown 308.3
2410 Female, age 72, unknown 251.2
1942 Male, age 51, unknown 232.7
2218 Male, age 76, both hemispheres 221.0
2021 Male, age 53, unknown 217.8
1915 Female, age 42, unknown 208.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

135.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 135.6
Samples: 139

Max nTPM: 363.9
Min nTPM: 25.5
Std nTPM: 72.2
Median nTPM: 123.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 363.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 328.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 322.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 312.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 304.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 302.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 296.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 289.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 278.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 266.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 256.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 248.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 247.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 246.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 235.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 225.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 225.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 224.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 222.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 219.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 217.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 212.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 211.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 207.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 204.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 201.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 198.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 196.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 189.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 186.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 185.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 183.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 179.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 176.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 175.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 171.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 171.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 168.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 166.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 165.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 164.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 161.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 158.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 157.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 153.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 152.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 152.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 150.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 149.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 148.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 147.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 145.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 144.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 144.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 143.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 140.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 139.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 138.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 135.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 134.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 134.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 132.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 132.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 132.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 129.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 129.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 128.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 128.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 125.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 123.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 122.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 119.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 118.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 117.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 110.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 110.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 110.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 108.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 104.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 104.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 102.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 102.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 102.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 102.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 99.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 95.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 93.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 93.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 92.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 92.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 91.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 89.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 84.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 83.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 82.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 82.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 81.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 81.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 80.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 80.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 79.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 79.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 78.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 78.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 77.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 77.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 76.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 76.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 76.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 74.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 73.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 73.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 73.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 73.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 73.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 71.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 70.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 67.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 66.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 66.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 65.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 64.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 64.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 64.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 61.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 61.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 61.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 57.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 56.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 55.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 51.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 50.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 46.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 46.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 46.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 42.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 26.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 26.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 25.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

308.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 308.7
FF:10158-103A5 76 years, female 308.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

179.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 179.7
Samples: 4

Max nTPM: 263.4
Min nTPM: 148.2
Sample A Female 151.4
Sample B Female 148.2
Sample C Male 155.6
Sample D Male 263.4
Midbrain
nTPM: 165.1
Samples: 4

Max nTPM: 251.8
Min nTPM: 106.3
Sample A Female 251.8
Sample B Female 188.9
Sample C Male 106.3
Sample D Male 113.4
Periaqueductal gray
nTPM: 130.5
Samples: 3

Max nTPM: 151.1
Min nTPM: 113.7
Sample B Female 151.1
Sample C Male 113.7
Sample D Male 126.7
Superior colliculi
nTPM: 123.4
Samples: 4

Max nTPM: 159.5
Min nTPM: 78.5
Sample A Female 126.0
Sample B Female 78.5
Sample C Male 129.7
Sample D Male 159.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

68.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 68.2
Samples: 4

Max nTPM: 69.5
Min nTPM: 67.0
Sample A Male 67.1
Sample B Male 67.0
Sample C Female 69.5
Sample D Female 69.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

7.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.8
69752041 Antisense, RP_050505_01_A02, Mouse strain C57BL/6J (56 days, male) 7.8

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