We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
MAP4K4
HPA
RESOURCES
  • TISSUE
  • BRAIN
  • SINGLE CELL
  • SUBCELLULAR
  • CANCER
  • BLOOD
  • CELL LINE
  • STRUCTURE & INTERACTION
ABOUT
  • INTRODUCTION
  • HISTORY
  • ORGANIZATION
  • PUBLICATIONS
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • ACKNOWLEDGMENTS
  • CONTACT
NEWS
  • NEWS ARTICLES
  • PRESS ROOM
LEARN
  • DICTIONARY
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
  • METHODS
  • EDUCATIONAL VIDEOS
DATA
  • DOWNLOADABLE DATA
  • PUBLICATION DATA
  • RELEASE HISTORY
HELP
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • HELP & FAQ
  • PRIVACY STATEMENT
  • LICENCE & CITATION
Fields »
Search result

Field
Term
Gene name
Class
Subclass
Class
Keyword
Chromosome
External id
Tissue
Cell type
Expression
Antibody panel
Tissue
Main location
Patient ID
Annotation
Tissue
Category
Tau score
Cluster
Reliability
Brain region
Category
Tau score
Brain region
Category
Tau score
Brain region
Category
Tau score
Cluster
Reliability
Tissue
Cell type
Enrichment
Cell type
Category
Tau score
Cell type
Category
Tau score
Cell type
Category
Tau score
Cell lineage
Category
Tau score
Cluster
Cluster
Location
Searches
Location
Cell line
Class
Type
Phase
Reliability
Cancer
Prognosis
Cancer
Category
Cancer
Category
Tau score
Cluster
Variants
Interacting gene (ensg_id)
Type
Number of interactions
Pathway
Category
Score
Score
Score
Validation
Validation
Validation
Validation
Antibodies
Data type
Column


  • SUMMARY

  • TISSUE

  • BRAIN

  • SINGLE CELL

  • SUBCELL

  • CANCER

  • BLOOD

  • CELL LINE

  • STRUCT & INT

  • MAP4K4
BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
HPA Brain:447.3 nTPM
FANTOM5:329.3 Scaled Tags Per Million
Pig:166.3 nTPM
Mouse:83.6 nTPM
Allen mouse:6.1 Expression energy

PONS AND MEDULLA - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

447.3
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 317.5
2301 Female, age 85, both hemispheres 383.8
2188 Female, age 91, both hemispheres 376.4
2090 Male, age 80, both hemispheres 339.5
1984 Male, age 76, both hemispheres 170.2
Area postrema
nTPM: 378.0
2306 Male, age 80, both hemispheres 459.1
2799 Male, age 61, both hemispheres 454.2
2054 Male, age 76, both hemispheres 220.6
Dorsal cochlear nucleus
nTPM: 282.9
2378 Male, age 80, both hemispheres 310.6
2187 Female, age 91, both hemispheres 302.0
2802 Male, age 74, right hemisphere 278.1
2370 Male, age 61, both hemispheres 270.5
2058 Male, age 76, both hemispheres 253.4
Dorsal medullary reticular nucleus
nTPM: 307.3
2373 Male, age 61, both hemispheres 343.9
2088 Male, age 76, both hemispheres 312.3
2040 Female, age 85, both hemispheres 265.8
Dorsal motor vagal complex
nTPM: 311.9
2797 Male, age 61, both hemispheres 505.9
2185 Male, age 76, both hemispheres 362.7
2807 Female, age 85, both hemispheres 350.7
2643 Male, age 74, both hemispheres 344.3
2000 Male, age 74, unknown 246.0
2813 Female, age 72, unknown 238.6
2133 Female, age 91, both hemispheres 228.2
2844 Male, age 55, unknown 219.1
Dorsal tegmental nucleus
nTPM: 298.6
2358 Male, age 61, both hemispheres 399.0
2083 Male, age 80, both hemispheres 310.5
2326 Male, age 74, both hemispheres 248.0
1936 Male, age 76, left hemisphere 237.0
Dorsolateral tegmental area
nTPM: 266.5
2337 Male, age 61, both hemispheres 385.6
2654 Male, age 80, both hemispheres 312.3
2751 Female, age 85, both hemispheres 273.4
2141 Male, age 76, both hemispheres 191.1
2360 Male, age 74, both hemispheres 170.3
Gigantocellular reticular nuclei, medullary
nTPM: 268.3
2314 Male, age 61, both hemispheres 360.9
2387 Female, age 91, both hemispheres 300.8
2310 Male, age 80, both hemispheres 278.5
1876 Female, age 85, both hemispheres 257.2
2022 Male, age 76, right hemisphere 245.8
2462 Male, age 74, both hemispheres 166.9
Gigantocellular reticular nuclei, pars
nTPM: 300.8
2330 Male, age 80, both hemispheres 367.5
2706 Male, age 80, both hemispheres 335.9
2336 Male, age 61, both hemispheres 300.6
2084 Female, age 85, both hemispheres 280.3
2168 Male, age 76, both hemispheres 220.0
Inferior olive
nTPM: 310.2
2628 Female, age 91, both hemispheres 394.7
2379 Male, age 80, both hemispheres 325.4
2178 Male, age 61, both hemispheres 313.5
2085 Female, age 85, both hemispheres 279.3
2563 Male, age 74, both hemispheres 238.0
Kolliker-Fuse nucleus
nTPM: 307.3
2793 Female, age 91, left hemisphere 400.7
2163 Male, age 80, both hemispheres 276.5
2315 Male, age 76, right hemisphere 244.8
Lateral lemniscal nuclei
nTPM: 250.6
2320 Female, age 91, left hemisphere 327.9
2746 Female, age 85, left hemisphere 264.5
2169 Male, age 76, both hemispheres 241.6
2453 Male, age 74, right hemisphere 228.3
2036 Male, age 80, both hemispheres 190.6
Lateral medullary reticular nucleus
nTPM: 323.0
2852 Male, age 80, both hemispheres 397.5
2374 Male, age 61, both hemispheres 393.8
2190 Female, age 85, both hemispheres 339.4
2804 Female, age 91, both hemispheres 287.9
2044 Male, age 76, both hemispheres 261.4
2305 Male, age 74, both hemispheres 258.1
Lateral parabrachial nucleus
nTPM: 331.9
2792 Male, age 76, both hemispheres 399.6
2790 Male, age 61, both hemispheres 367.5
2013 Male, age 80, both hemispheres 329.2
2139 Female, age 85, right hemisphere 231.1
Lateral vestibular nucleus
nTPM: 288.1
2311 Male, age 80, both hemispheres 310.5
2184 Male, age 76, both hemispheres 265.7
Locus coeruleus
nTPM: 176.5
2720 Male, age 74, both hemispheres 249.0
2162 Male, age 80, both hemispheres 209.7
2317 Female, age 72, unknown 165.9
2123 Female, age 91, both hemispheres 161.9
2788 Male, age 74, unknown 156.0
2014 Male, age 55, unknown 146.5
1980 Male, age 76, both hemispheres 146.3
Medial olivary nucleus
nTPM: 366.7
1962 Male, age 76, both hemispheres 403.0
1943 Male, age 61, both hemispheres 382.4
2851 Male, age 80, both hemispheres 379.9
2138 Female, age 91, both hemispheres 301.5
Medial parabrachial nucleus
nTPM: 308.0
2156 Male, age 61, both hemispheres 368.7
2170 Female, age 91, both hemispheres 315.3
2854 Male, age 80, both hemispheres 296.9
2786 Male, age 76, both hemispheres 295.5
2463 Female, age 85, right hemisphere 263.5
Medial periolivary nuclei
nTPM: 247.6
2081 Male, age 80, both hemispheres 321.5
2458 Female, age 91, both hemispheres 313.4
2063 Male, age 76, both hemispheres 221.0
2171 Female, age 85, both hemispheres 191.6
2791 Male, age 74, right hemisphere 190.4
Medial vestibular nucleus
nTPM: 247.3
2803 Female, age 91, both hemispheres 304.5
2624 Male, age 61, both hemispheres 288.6
2093 Male, age 80, both hemispheres 279.6
2801 Male, age 74, both hemispheres 237.0
2743 Female, age 85, both hemispheres 200.5
2134 Male, age 76, both hemispheres 173.7
Motor facial nucleus
nTPM: 278.7
2697 Female, age 85, both hemispheres 382.1
2327 Male, age 80, both hemispheres 308.1
2795 Female, age 91, both hemispheres 293.7
2126 Male, age 61, both hemispheres 255.1
2365 Male, age 74, right hemisphere 232.0
2062 Male, age 76, both hemispheres 201.3
Motor hypoglossal nucleus
nTPM: 298.6
2182 Male, age 80, both hemispheres 411.9
2132 Female, age 85, both hemispheres 356.1
2125 Female, age 91, both hemispheres 284.5
2461 Male, age 61, both hemispheres 263.4
2277 Male, age 76, both hemispheres 176.9
Motor trigeminal nucleus
nTPM: 287.9
2321 Female, age 91, both hemispheres 334.3
2309 Male, age 76, both hemispheres 309.7
2335 Male, age 61, both hemispheres 280.7
2079 Male, age 80, both hemispheres 279.3
2560 Male, age 74, both hemispheres 235.6
Nuclei of the trapezoid body
nTPM: 237.1
2166 Male, age 80, both hemispheres 332.0
2368 Female, age 91, both hemispheres 279.8
1983 Male, age 76, both hemispheres 215.9
2159 Male, age 61, both hemispheres 192.2
2735 Female, age 85, both hemispheres 165.4
Nucleus ambiguus
nTPM: 335.5
2071 Male, age 76, both hemispheres 362.8
2096 Female, age 85, both hemispheres 308.2
Nucleus cuneatus
nTPM: 362.1
2805 Female, age 91, both hemispheres 443.0
2380 Male, age 80, both hemispheres 442.0
2381 Male, age 80, both hemispheres 434.4
2808 Female, age 85, both hemispheres 407.5
2100 Male, age 76, both hemispheres 345.4
2564 Male, age 74, both hemispheres 330.4
2562 Male, age 61, both hemispheres 310.7
2376 Male, age 61, both hemispheres 290.1
2131 Male, age 76, both hemispheres 255.1
Nucleus gracilis
nTPM: 447.3
2382 Male, age 80, both hemispheres 560.7
2299 Female, age 85, both hemispheres 421.0
2627 Male, age 74, both hemispheres 360.4
Nucleus raphe magnus
nTPM: 237.6
2328 Male, age 80, both hemispheres 332.3
2051 Male, age 76, both hemispheres 285.7
2459 Female, age 91, both hemispheres 280.7
2455 Male, age 74, both hemispheres 208.6
2172 Female, age 85, both hemispheres 169.8
2160 Male, age 61, both hemispheres 148.2
Nucleus raphe obscurus
nTPM: 372.0
2142 Male, age 76, midline 425.5
2845 Female, age 85, midline 372.4
2800 Male, age 61, midline 317.9
Nucleus raphe pallidus
nTPM: 344.7
2145 Male, age 76, midline 439.1
1924 Male, age 61, midline 309.3
2183 Male, age 80, midline 285.6
Nucleus tractus solitarii
nTPM: 193.8
2307 Male, age 80, both hemispheres 225.7
2191 Female, age 85, both hemispheres 214.8
2656 Male, age 76, both hemispheres 183.6
2144 Female, age 91, right hemisphere 151.1
Paramedian reticular nucleus
nTPM: 255.4
2052 Male, age 76, both hemispheres 314.1
2057 Male, age 80, both hemispheres 260.8
2313 Male, age 61, both hemispheres 226.8
2050 Female, age 85, both hemispheres 219.9
Parvicellular reticular nuclei
nTPM: 274.9
2095 Male, age 76, both hemispheres 312.8
2119 Male, age 80, both hemispheres 285.0
2558 Male, age 74, both hemispheres 226.9
Parvicellular reticular nuclei, medullary
nTPM: 278.7
2181 Male, age 80, left hemisphere 290.3
2189 Female, age 91, both hemispheres 275.1
2091 Female, age 85, both hemispheres 270.7
Pedunculopontine tegmental nucleus
nTPM: 278.1
2338 Male, age 61, both hemispheres 350.7
2334 Male, age 80, both hemispheres 272.1
1921 Female, age 85, both hemispheres 211.5
Peritrigeminal nucleus
nTPM: 283.8
2067 Female, age 85, both hemispheres 293.6
2136 Male, age 76, both hemispheres 289.4
2179 Male, age 61, both hemispheres 268.4
Pontine nuclei
nTPM: 255.1
2115 Male, age 80, left hemisphere 343.6
2319 Female, age 91, both hemispheres 338.7
1968 Male, age 76, left hemisphere 290.6
2109 Female, age 72, unknown 250.7
1863 Male, age 55, unknown 248.9
2454 Male, age 74, left hemisphere 246.1
2787 Female, age 85, both hemispheres 183.0
2727 Male, age 61, right hemisphere 139.2
Pontine raphe nucleus
nTPM: 201.9
2122 Female, age 85, midline 206.2
2853 Male, age 76, midline 197.7
Posteroventral cochlear nucleus
nTPM: 343.2
2135 Female, age 91, both hemispheres 435.5
2341 Male, age 80, both hemispheres 408.2
2371 Male, age 61, both hemispheres 336.6
2070 Male, age 76, both hemispheres 307.5
2752 Female, age 85, both hemispheres 228.2
Prepositus hypoglossal nucleus
nTPM: 234.9
2855 Female, age 85, right hemisphere 266.0
2086 Male, age 80, both hemispheres 203.8
Principal sensory trigeminal nucleus
nTPM: 253.1
2367 Female, age 91, left hemisphere 342.0
2324 Male, age 76, both hemispheres 277.4
2008 Male, age 80, left hemisphere 202.7
2158 Male, age 61, both hemispheres 190.5
Reticular pontine nucleus, caudal
nTPM: 278.3
2092 Male, age 76, both hemispheres 288.5
2457 Female, age 91, both hemispheres 283.6
2559 Male, age 74, both hemispheres 276.4
2332 Male, age 80, right hemisphere 264.8
Reticular pontine nucleus, oral
nTPM: 285.4
2366 Female, age 91, both hemispheres 422.4
1939 Male, age 80, both hemispheres 294.9
2167 Male, age 76, both hemispheres 286.6
2012 Female, age 85, both hemispheres 227.0
2361 Male, age 74, both hemispheres 196.0
Reticulotegmental nucleus
nTPM: 271.6
2322 Female, age 91, both hemispheres 312.5
2333 Male, age 80, both hemispheres 285.3
2452 Male, age 74, both hemispheres 275.4
2325 Male, age 76, both hemispheres 213.4
Spinal trigeminal nucleus, caudal
nTPM: 311.4
2308 Male, age 80, both hemispheres 388.4
2642 Male, age 74, both hemispheres 333.9
2312 Male, age 61, both hemispheres 313.6
2447 Male, age 76, both hemispheres 262.2
2390 Female, age 91, both hemispheres 258.9
Spinal trigeminal nucleus, interpolar
nTPM: 253.5
2389 Female, age 91, both hemispheres 280.4
2033 Male, age 80, both hemispheres 279.3
2386 Female, age 85, both hemispheres 265.2
2625 Male, age 61, both hemispheres 242.8
2066 Male, age 76, right hemisphere 200.1
Spinal trigeminal nucleus, oral
nTPM: 240.7
2164 Male, age 80, both hemispheres 300.1
1978 Male, age 76, both hemispheres 238.9
2737 Female, age 85, both hemispheres 183.1
Spinal vestibular nucleus
nTPM: 308.0
2384 Male, age 74, both hemispheres 352.4
2806 Female, age 85, both hemispheres 318.1
2748 Male, age 76, both hemispheres 316.9
2780 Male, age 80, both hemispheres 296.1
2796 Male, age 61, both hemispheres 288.2
2186 Female, age 91, both hemispheres 276.1
Subcoeruleus area
nTPM: 264.5
2369 Female, age 85, left hemisphere 319.2
2451 Male, age 74, both hemispheres 278.4
2089 Male, age 76, left hemisphere 262.0
1958 Male, age 80, both hemispheres 245.4
2323 Female, age 91, left hemisphere 217.6
Superior olive
nTPM: 280.6
2561 Female, age 91, both hemispheres 338.9
2329 Male, age 80, right hemisphere 336.5
2020 Male, age 76, both hemispheres 324.4
1875 Female, age 85, both hemispheres 214.2
2364 Male, age 74, right hemisphere 189.1
Superior vestibular nucleus
nTPM: 223.9
2015 Male, age 80, both hemispheres 265.7
2061 Male, age 76, both hemispheres 223.5
2383 Male, age 74, both hemispheres 182.5
Ventral medullary reticular nucleus
nTPM: 319.9
2372 Male, age 61, both hemispheres 329.0
2060 Male, age 76, both hemispheres 310.7
Ventral periolivary nuclei
nTPM: 274.7
2023 Male, age 76, both hemispheres 345.1
2794 Female, age 91, left hemisphere 278.5
2165 Male, age 80, both hemispheres 276.5
2130 Female, age 85, both hemispheres 198.8
Ventrolateral medulla, A1-C1 cell groups
nTPM: 296.9
2118 Male, age 80, both hemispheres 395.9
2302 Female, age 91, both hemispheres 282.9
2180 Male, age 61, both hemispheres 273.0
1986 Male, age 76, both hemispheres 269.7
2741 Female, age 85, both hemispheres 263.0
Ventrolateral tegmental area, A5 NE cell group
nTPM: 287.1
2359 Male, age 61, both hemispheres 345.9
2161 Male, age 80, both hemispheres 309.0
2456 Female, age 91, both hemispheres 293.7
1959 Male, age 76, both hemispheres 283.7
2840 Female, age 85, both hemispheres 278.9
2449 Male, age 74, both hemispheres 211.4

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

329.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 329.3
FF:10182-103D2 60 years, female 418.0
FF:10165-103B3 76 years, female 240.5
Medulla oblongata
Scaled Tags Per Million: 195.4
FF:10174-103C3 60 years, female 216.2
FF:10155-103A2 76 years, female 203.9
FF:10038-101F2 18-64 years, mixed 166.1
Pons
Scaled Tags Per Million: 160.8
FF:10033-101E6 18-54 years, mixed 160.8

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

166.3
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 166.3
Samples: 4

Max nTPM: 182.7
Min nTPM: 145.5
Sample A Female 145.5
Sample B Female 164.2
Sample C Male 182.7
Sample D Male 172.7
Pons
nTPM: 135.4
Samples: 4

Max nTPM: 172.8
Min nTPM: 112.0
Sample A Female 112.0
Sample B Female 121.0
Sample C Male 135.8
Sample D Male 172.8

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

83.6
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 83.6
Samples: 4

Max nTPM: 84.6
Min nTPM: 82.2
Sample A Male 84.6
Sample B Male 82.2
Sample C Female 83.2
Sample D Female 84.4

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

6.1
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 6.1
69752041 Antisense, RP_050505_01_A02, Mouse strain C57BL/6J (56 days, male) 6.1
Pons
Expression energy: 5.7
69752041 Antisense, RP_050505_01_A02, Mouse strain C57BL/6J (56 days, male) 5.7

Contact

  • NEWS ARTICLES
  • PRESS ROOM

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS

The Human Protein Atlas

  • DOWNLOADABLE DATA
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


contact@proteinatlas.org