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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:85.4 nTPM
HPA Brain:77.1 nTPM
GTEx:85.4 nTPM
FANTOM5:115.3 Scaled Tags Per Million
Pig:35.6 nTPM
Mouse:50.6 nTPM
Allen mouse:16.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

77.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 63.2
2019 Male, age 18, unknown 90.3
2828 Female, age 72, unknown 78.6
2586 Male, age 75, left hemisphere 67.3
1870 Female, age 42, unknown 66.3
1827 Male, age 72, unknown 60.5
2411 Female, age 72, unknown 57.7
1833 Male, age 53, unknown 54.9
2666 Male, age 74, left hemisphere 54.2
1830 Male, age 51, unknown 51.6
2219 Male, age 76, both hemispheres 50.6
Dorsal raphe nucleus
nTPM: 69.1
1828 Male, age 53, unknown 82.8
2016 Female, age 72, unknown 74.1
2047 Male, age 72, unknown 74.1
2298 Female, age 72, unknown 60.3
2750 Male, age 76, both hemispheres 54.2
Inferior colliculus
nTPM: 58.7
1890 Male, age 53, unknown 66.4
2097 Female, age 72, unknown 61.4
1848 Female, age 42, unknown 58.7
2849 Male, age 72, unknown 48.5
Median raphe nucleus
nTPM: 48.4
2220 Male, age 76, midline 48.4
Periaquaductal grey, anterior
nTPM: 61.1
1795 Male, age 51, unknown 66.5
1947 Male, age 18, unknown 62.9
2502 Female, age 75, unknown 53.9
Periaquaductal grey, dorsal
nTPM: 60.5
2850 Male, age 76, both hemispheres 73.4
2464 Female, age 72, unknown 58.3
1831 Male, age 72, unknown 58.0
1840 Male, age 53, unknown 52.3
Periaquaductal grey, lateral
nTPM: 65.7
2272 Male, age 74, both hemispheres 76.4
2140 Male, age 76, both hemispheres 67.8
2053 Male, age 18, unknown 53.0
Pretectal area
nTPM: 69.5
2667 Female, age 75, unknown 84.9
2273 Male, age 74, both hemispheres 79.6
1944 Female, age 72, unknown 77.5
1817 Female, age 42, unknown 77.1
1816 Male, age 51, unknown 74.4
2007 Male, age 72, unknown 71.8
1815 Male, age 53, unknown 69.4
2407 Male, age 75, both hemispheres 67.8
2224 Female, age 72, unknown 56.9
2316 Male, age 76, right hemisphere 55.9
2825 Male, age 18, unknown 49.5
Red nucleus
nTPM: 74.4
2725 Female, age 75, unknown 89.0
2785 Male, age 18, unknown 83.6
1954 Female, age 42, unknown 80.7
2588 Male, age 74, left hemisphere 79.0
1821 Female, age 72, unknown 77.9
1865 Male, age 51, unknown 75.2
1904 Male, age 53, unknown 72.7
2769 Male, age 72, unknown 71.7
2503 Female, age 72, unknown 71.5
2227 Male, age 72, unknown 71.0
2823 Male, age 76, right hemisphere 70.7
2584 Male, age 75, left hemisphere 49.3
Substantia nigra
nTPM: 77.1
1916 Female, age 42, unknown 113.4
1851 Male, age 51, unknown 98.2
2409 Female, age 72, unknown 83.9
2699 Male, age 18, unknown 78.2
2241 Male, age 72, unknown 76.2
1941 Male, age 53, unknown 73.5
2665 Male, age 74, both hemispheres 64.7
2590 Female, age 75, unknown 64.6
1889 Female, age 72, unknown 64.0
2583 Male, age 75, right hemisphere 54.5
Superior colliculus
nTPM: 62.2
1995 Male, age 72, unknown 73.6
2087 Female, age 72, unknown 73.5
1913 Female, age 42, unknown 68.2
2664 Male, age 75, both hemispheres 66.3
1796 Male, age 53, unknown 61.1
2261 Male, age 18, unknown 59.3
2587 Male, age 74, left hemisphere 57.3
1895 Male, age 76, right hemisphere 56.1
2668 Female, age 75, unknown 54.5
1839 Male, age 51, unknown 52.0
Ventral tegmental area
nTPM: 66.5
1915 Female, age 42, unknown 87.7
2410 Female, age 72, unknown 69.5
2021 Male, age 53, unknown 64.4
2218 Male, age 76, both hemispheres 61.0
1942 Male, age 51, unknown 59.8
2223 Female, age 72, unknown 56.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

85.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 85.4
Samples: 139

Max nTPM: 176.5
Min nTPM: 30.0
Std nTPM: 22.8
Median nTPM: 82.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 176.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 162.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 148.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 144.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 131.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 126.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 124.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 124.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 121.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 121.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 120.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 120.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 116.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 114.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 114.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 111.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 111.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 110.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 109.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 109.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 108.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 108.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 107.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 106.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 105.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 104.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 103.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 102.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 100.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 100.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 100.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 100.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 98.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 98.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 97.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 96.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 96.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 95.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 95.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 94.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 94.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 93.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 92.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 92.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 92.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 91.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 91.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 90.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 89.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 89.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 88.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 87.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 87.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 87.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 87.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 86.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 86.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 86.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 86.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 86.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 86.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 85.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 85.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 85.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 84.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 83.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 83.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 82.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 82.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 82.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 82.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 82.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 82.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 81.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 81.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 80.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 80.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 80.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 79.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 79.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 79.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 78.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 78.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 78.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 77.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 76.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 76.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 75.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 75.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 75.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 74.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 74.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 74.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 74.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 72.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 72.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 72.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 72.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 71.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 70.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 70.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 70.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 69.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 68.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 68.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 68.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 67.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 67.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 66.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 66.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 65.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 65.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 65.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 65.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 64.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 64.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 64.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 64.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 64.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 63.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 62.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 62.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 61.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 61.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 61.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 60.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 60.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 60.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 60.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 59.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 57.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 57.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 55.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 54.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 49.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 49.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 49.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 46.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 30.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

115.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 115.3
FF:10158-103A5 76 years, female 115.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

35.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 35.7
Samples: 4

Max nTPM: 41.7
Min nTPM: 29.0
Sample A Female 41.7
Sample B Female 29.0
Sample C Male 38.3
Sample D Male 33.6
Midbrain
nTPM: 31.8
Samples: 4

Max nTPM: 41.1
Min nTPM: 25.2
Sample A Female 41.1
Sample B Female 30.2
Sample C Male 30.8
Sample D Male 25.2
Periaqueductal gray
nTPM: 25.8
Samples: 3

Max nTPM: 28.3
Min nTPM: 21.1
Sample B Female 27.9
Sample C Male 28.3
Sample D Male 21.1
Superior colliculi
nTPM: 33.9
Samples: 4

Max nTPM: 40.3
Min nTPM: 27.6
Sample A Female 35.1
Sample B Female 40.3
Sample C Male 32.7
Sample D Male 27.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

50.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 50.6
Samples: 4

Max nTPM: 53.6
Min nTPM: 46.6
Sample A Male 53.6
Sample B Male 49.4
Sample C Female 46.6
Sample D Female 52.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

16.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 16.6
227161 Antisense, RP_040604_02_A03, Mouse strain C57BL/6J (56 days, male) 28.0
68203485 Antisense, RP_041208_01_C05, Mouse strain C57BL/6J (56 days, male) 5.3

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