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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
Low
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
101.7
nTPM
HPA:
101.7
nTPM
GTEx:
84.7
nTPM
FANTOM5:
274.7
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA040736
Cholangiocytes
Low
Hepatocytes
Low
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
101.7
Female, age 60
Liver sample 21 nTPM: 116.6
Male, age 54
Liver sample 23 nTPM: 134.3
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 108.9
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 68.8
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 70.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 104
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 104.9
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 99.7
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 87.2
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 122
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
84.7
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 84.7
Samples: 226
Max nTPM: 233.7
Min nTPM: 46.9
Std nTPM: 20.8
Median nTPM: 80.8
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
233.7
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
142.8
GTEX-14XAO-0226-SM-68728
60-69 years, female
139.4
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
137.5
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
136.6
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
131.4
GTEX-14PJO-1726-SM-68719
60-69 years, male
129.5
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
127.5
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
127.5
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
127.2
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
123.2
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
122.3
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
119.6
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
119.0
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
117.1
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
114.2
GTEX-S32W-1926-SM-4AD63
50-59 years, female
113.5
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
113.1
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
113.0
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
110.2
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
109.6
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
107.9
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
107.3
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
107.2
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
106.5
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
106.3
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
105.8
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
105.6
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
105.6
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
105.2
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
104.3
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
103.6
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
103.6
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
103.1
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
102.9
GTEX-REY6-1226-SM-48FDR
60-69 years, male
102.8
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
102.6
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
102.4
GTEX-Q734-0326-SM-48U15
40-49 years, female
102.3
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
102.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
101.9
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
101.1
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
100.9
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
100.7
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
99.7
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
99.6
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
99.0
GTEX-X261-1726-SM-4PQYT
50-59 years, male
98.3
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
98.3
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
98.2
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
97.6
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
97.6
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
97.2
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
96.2
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
95.9
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
95.2
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
94.9
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
94.9
GTEX-QEL4-1226-SM-447A4
50-59 years, male
94.6
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
94.5
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
93.2
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
92.9
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
92.8
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
92.3
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
91.6
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
91.5
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
91.2
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
90.0
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
90.0
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
89.7
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
89.5
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
89.5
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
89.4
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
89.4
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
89.2
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
89.1
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
88.9
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
88.1
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
88.1
GTEX-13113-1326-SM-5GCOI
60-69 years, female
87.5
GTEX-14PHX-0526-SM-664NW
50-59 years, male
87.1
GTEX-QESD-2026-SM-447BI
20-29 years, male
86.7
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
86.5
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
86.5
GTEX-S33H-1626-SM-4AD68
30-39 years, male
86.2
GTEX-R53T-0326-SM-48FEC
50-59 years, female
86.0
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
85.9
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
85.9
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
85.9
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
85.7
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
85.3
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
85.1
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
84.8
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
84.7
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
84.6
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
84.4
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
84.1
GTEX-18A66-2026-SM-7189C
60-69 years, male
83.7
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
83.7
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
83.6
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
83.2
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
82.9
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
82.6
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
82.4
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
82.3
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
82.3
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
82.0
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
81.9
GTEX-14JG1-1626-SM-664NH
40-49 years, male
81.8
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
81.6
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
81.3
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
81.1
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
80.9
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
80.8
GTEX-1B932-1426-SM-793AN
40-49 years, female
80.7
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
80.7
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
80.6
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
80.5
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
80.3
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
80.3
GTEX-17F96-1226-SM-79OK2
70-79 years, male
80.1
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
79.8
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
79.6
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
79.3
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
79.3
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
79.3
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
79.2
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
79.1
GTEX-P78B-1326-SM-3P611
40-49 years, female
78.7
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
78.0
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
77.9
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
77.6
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
77.2
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
76.6
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
76.6
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
76.4
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
76.3
GTEX-11ZUS-2526-SM-59872
30-39 years, male
76.2
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
76.1
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
75.9
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
75.8
GTEX-RU72-1426-SM-46MUF
50-59 years, female
75.7
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
75.7
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
75.4
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
75.4
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
75.3
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
75.3
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
75.0
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
74.8
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
74.7
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
74.6
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
74.5
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
74.3
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
74.3
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
74.1
GTEX-O5YV-0726-SM-EV798
60-69 years, female
73.9
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
73.8
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
73.7
GTEX-17HHE-0126-SM-79398
50-59 years, male
73.1
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
72.9
GTEX-12696-0826-SM-5EGGE
60-69 years, male
72.8
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
72.7
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
72.6
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
72.5
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
71.8
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
71.7
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
71.6
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
71.5
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
71.5
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
71.4
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
71.1
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
71.1
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
71.0
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
71.0
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
70.8
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
70.8
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
70.4
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
69.9
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
69.9
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
69.9
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
69.5
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
69.5
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
69.5
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
69.4
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
69.3
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
69.0
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
69.0
GTEX-14E7W-1526-SM-6871X
70-79 years, male
68.8
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
68.8
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
68.7
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
68.2
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
68.2
GTEX-1B933-1226-SM-731DW
50-59 years, female
67.7
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
67.5
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
67.1
GTEX-1399T-0826-SM-5IFES
60-69 years, male
66.5
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
65.8
GTEX-18A7A-1526-SM-72D69
50-59 years, female
65.8
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
65.0
GTEX-144GL-1426-SM-79OMA
50-59 years, male
63.9
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
63.5
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
62.9
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
62.7
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
62.4
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
62.1
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
61.6
GTEX-YECK-1926-SM-4W21H
60-69 years, male
61.4
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
61.4
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
61.2
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
61.0
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
60.5
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
60.1
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
59.9
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
59.2
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
59.0
GTEX-13112-1426-SM-5EGH8
50-59 years, male
58.8
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
58.2
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
57.3
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
56.9
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
54.7
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
53.9
GTEX-18465-1626-SM-7LG6N
50-59 years, male
53.1
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
50.9
GTEX-RN64-1826-SM-48FDV
50-59 years, male
50.8
GTEX-11GSP-0626-SM-5986T
60-69 years, female
46.9
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
46.9
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
