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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
115.4
nTPM
HPA:
5.2
nTPM
GTEx:
115.4
nTPM
FANTOM5:
171.7
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA008874
Cholangiocytes
Not detected
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
5.2
Female, age 60
Liver sample 21 nTPM: 8
Male, age 54
Liver sample 23 nTPM: 8.8
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 3.5
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 6.7
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 4.3
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 4.8
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 6.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 4.1
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 2
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 3.6
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
115.4
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 115.4
Samples: 226
Max nTPM: 1092.0
Min nTPM: 27.2
Std nTPM: 112.4
Median nTPM: 86.5
GTEX-14PHX-0526-SM-664NW
50-59 years, male
1092.0
GTEX-18A66-2026-SM-7189C
60-69 years, male
741.8
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
567.2
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
538.0
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
440.6
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
421.2
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
401.0
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
399.4
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
379.3
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
328.4
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
293.0
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
287.2
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
251.8
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
251.2
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
238.1
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
230.9
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
227.4
GTEX-R53T-0326-SM-48FEC
50-59 years, female
226.7
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
215.9
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
202.2
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
199.5
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
194.4
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
189.9
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
188.5
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
188.3
GTEX-P78B-1326-SM-3P611
40-49 years, female
173.4
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
168.8
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
168.6
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
164.5
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
163.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
162.7
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
159.4
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
158.3
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
156.4
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
155.1
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
153.3
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
152.9
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
152.9
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
152.7
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
152.1
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
148.7
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
146.0
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
145.9
GTEX-RN64-1826-SM-48FDV
50-59 years, male
144.1
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
142.3
GTEX-1399T-0826-SM-5IFES
60-69 years, male
141.8
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
140.6
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
139.5
GTEX-144GL-1426-SM-79OMA
50-59 years, male
139.0
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
138.8
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
137.9
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
137.6
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
135.7
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
134.1
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
133.1
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
131.9
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
131.9
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
129.3
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
129.3
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
129.0
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
128.8
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
128.5
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
127.4
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
123.7
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
123.5
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
123.2
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
123.0
GTEX-14E7W-1526-SM-6871X
70-79 years, male
122.7
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
121.7
GTEX-QESD-2026-SM-447BI
20-29 years, male
121.6
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
121.5
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
120.0
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
119.9
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
117.2
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
117.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
115.9
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
114.0
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
112.8
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
112.7
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
112.6
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
112.6
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
111.1
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
110.6
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
110.3
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
109.3
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
107.2
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
106.7
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
105.7
GTEX-17HHE-0126-SM-79398
50-59 years, male
105.6
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
105.4
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
104.4
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
102.9
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
102.2
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
101.9
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
99.8
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
98.6
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
97.0
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
97.0
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
95.3
GTEX-18465-1626-SM-7LG6N
50-59 years, male
95.3
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
93.6
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
92.5
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
92.1
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
91.9
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
91.2
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
89.5
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
89.3
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
89.0
GTEX-O5YV-0726-SM-EV798
60-69 years, female
88.4
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
88.3
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
87.4
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
86.7
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
86.5
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
86.5
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
85.6
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
84.8
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
84.4
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
84.3
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
84.3
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
84.1
GTEX-13113-1326-SM-5GCOI
60-69 years, female
83.9
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
82.7
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
82.4
GTEX-17F96-1226-SM-79OK2
70-79 years, male
80.7
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
79.9
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
79.1
GTEX-18A7A-1526-SM-72D69
50-59 years, female
78.7
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
78.4
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
76.9
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
76.5
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
75.1
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
75.0
GTEX-11GSP-0626-SM-5986T
60-69 years, female
74.8
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
74.8
GTEX-S32W-1926-SM-4AD63
50-59 years, female
74.2
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
74.0
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
74.0
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
73.5
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
73.4
GTEX-14JG1-1626-SM-664NH
40-49 years, male
72.4
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
72.3
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
72.1
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
72.0
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
71.5
GTEX-11ZUS-2526-SM-59872
30-39 years, male
70.4
GTEX-Q734-0326-SM-48U15
40-49 years, female
69.6
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
69.4
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
68.5
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
68.2
GTEX-QEL4-1226-SM-447A4
50-59 years, male
67.9
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
67.9
GTEX-13112-1426-SM-5EGH8
50-59 years, male
66.3
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
66.2
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
66.0
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
64.9
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
64.8
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
64.6
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
64.4
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
63.2
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
63.1
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
62.4
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
62.4
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
62.2
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
62.1
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
61.2
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
60.6
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
60.3
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
60.1
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
60.1
GTEX-1B932-1426-SM-793AN
40-49 years, female
59.9
GTEX-YECK-1926-SM-4W21H
60-69 years, male
59.1
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
57.8
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
57.7
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
57.6
GTEX-14XAO-0226-SM-68728
60-69 years, female
57.5
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
56.3
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
55.7
GTEX-RU72-1426-SM-46MUF
50-59 years, female
55.0
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
54.2
GTEX-S33H-1626-SM-4AD68
30-39 years, male
53.7
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
53.3
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
52.9
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
52.7
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
52.1
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
52.0
GTEX-1B933-1226-SM-731DW
50-59 years, female
51.0
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
50.5
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
49.8
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
49.6
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
48.8
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
48.7
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
48.1
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
47.8
GTEX-REY6-1226-SM-48FDR
60-69 years, male
45.9
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
45.2
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
45.0
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
44.9
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
44.7
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
43.7
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
43.4
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
42.9
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
42.2
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
41.9
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
40.6
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
39.5
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
38.8
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
38.5
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
38.1
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
37.9
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
37.9
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
37.6
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
37.3
GTEX-X261-1726-SM-4PQYT
50-59 years, male
37.1
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
36.7
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
36.6
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
36.3
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
35.6
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
33.9
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
33.8
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
33.2
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
33.1
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
32.7
GTEX-12696-0826-SM-5EGGE
60-69 years, male
30.5
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
29.2
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
28.5
GTEX-14PJO-1726-SM-68719
60-69 years, male
27.2
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
