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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:87.9 nTPM
HPA Brain:86.7 nTPM
GTEx:87.9 nTPM
FANTOM5:54.5 Scaled Tags Per Million
Pig:63.2 nTPM
Mouse:68.8 nTPM
Allen mouse:3.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

86.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 59.9
2411 Female, age 72, unknown 80.1
1827 Male, age 72, unknown 66.8
2828 Female, age 72, unknown 63.1
2666 Male, age 74, left hemisphere 60.5
1833 Male, age 53, unknown 57.0
1870 Female, age 42, unknown 57.0
2019 Male, age 18, unknown 56.8
1830 Male, age 51, unknown 53.6
2586 Male, age 75, left hemisphere 52.3
2219 Male, age 76, both hemispheres 51.5
Dorsal raphe nucleus
nTPM: 80.5
2047 Male, age 72, unknown 98.4
2298 Female, age 72, unknown 97.7
1828 Male, age 53, unknown 74.2
2750 Male, age 76, both hemispheres 68.0
2016 Female, age 72, unknown 64.4
Inferior colliculus
nTPM: 67.4
2097 Female, age 72, unknown 75.4
1890 Male, age 53, unknown 74.8
1848 Female, age 42, unknown 64.5
2849 Male, age 72, unknown 54.6
Median raphe nucleus
nTPM: 77.3
2220 Male, age 76, midline 77.3
Periaquaductal grey, anterior
nTPM: 62.2
1947 Male, age 18, unknown 72.4
1795 Male, age 51, unknown 59.1
2502 Female, age 75, unknown 55.3
Periaquaductal grey, dorsal
nTPM: 56.5
1840 Male, age 53, unknown 63.5
2464 Female, age 72, unknown 57.4
2850 Male, age 76, both hemispheres 52.8
1831 Male, age 72, unknown 52.2
Periaquaductal grey, lateral
nTPM: 54.7
2272 Male, age 74, both hemispheres 58.0
2053 Male, age 18, unknown 53.8
2140 Male, age 76, both hemispheres 52.4
Pretectal area
nTPM: 59.7
1816 Male, age 51, unknown 67.1
2667 Female, age 75, unknown 67.0
2224 Female, age 72, unknown 66.2
2273 Male, age 74, both hemispheres 64.5
1944 Female, age 72, unknown 62.1
2007 Male, age 72, unknown 61.8
2825 Male, age 18, unknown 60.7
1817 Female, age 42, unknown 58.7
2316 Male, age 76, right hemisphere 51.2
1815 Male, age 53, unknown 49.5
2407 Male, age 75, both hemispheres 48.2
Red nucleus
nTPM: 54.1
1821 Female, age 72, unknown 74.6
2725 Female, age 75, unknown 58.3
1954 Female, age 42, unknown 55.9
2227 Male, age 72, unknown 54.9
2769 Male, age 72, unknown 54.5
2584 Male, age 75, left hemisphere 53.8
2503 Female, age 72, unknown 52.9
2823 Male, age 76, right hemisphere 50.7
1865 Male, age 51, unknown 49.9
2785 Male, age 18, unknown 49.2
2588 Male, age 74, left hemisphere 47.9
1904 Male, age 53, unknown 46.2
Substantia nigra
nTPM: 86.7
1941 Male, age 53, unknown 115.4
1916 Female, age 42, unknown 109.8
1851 Male, age 51, unknown 98.9
2241 Male, age 72, unknown 92.2
2409 Female, age 72, unknown 83.4
2699 Male, age 18, unknown 81.6
2665 Male, age 74, both hemispheres 77.8
1889 Female, age 72, unknown 75.7
2590 Female, age 75, unknown 71.5
2583 Male, age 75, right hemisphere 60.5
Superior colliculus
nTPM: 54.4
2587 Male, age 74, left hemisphere 63.8
1839 Male, age 51, unknown 59.0
1895 Male, age 76, right hemisphere 58.8
2668 Female, age 75, unknown 58.7
1796 Male, age 53, unknown 56.6
2087 Female, age 72, unknown 56.6
2261 Male, age 18, unknown 54.6
2664 Male, age 75, both hemispheres 48.2
1913 Female, age 42, unknown 44.1
1995 Male, age 72, unknown 43.4
Ventral tegmental area
nTPM: 74.5
1915 Female, age 42, unknown 93.1
2410 Female, age 72, unknown 89.4
2218 Male, age 76, both hemispheres 76.0
1942 Male, age 51, unknown 63.8
2021 Male, age 53, unknown 63.2
2223 Female, age 72, unknown 61.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

87.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 87.9
Samples: 139

Max nTPM: 272.3
Min nTPM: 49.1
Std nTPM: 27.1
Median nTPM: 83.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 272.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 197.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 170.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 143.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 136.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 131.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 130.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 127.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 124.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 120.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 119.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 118.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 117.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 116.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 115.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 114.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 113.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 113.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 112.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 109.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 108.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 108.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 108.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 104.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 104.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 103.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 103.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 103.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 102.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 102.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 100.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 100.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 98.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 96.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 95.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 94.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 94.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 93.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 93.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 93.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 92.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 91.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 90.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 90.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 90.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 90.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 90.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 89.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 89.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 89.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 88.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 88.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 88.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 88.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 87.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 87.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 87.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 87.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 86.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 86.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 85.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 85.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 85.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 85.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 84.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 84.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 84.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 84.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 83.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 83.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 82.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 81.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 81.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 81.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 81.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 80.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 80.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 80.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 79.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 79.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 79.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 78.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 78.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 78.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 77.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 77.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 77.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 77.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 76.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 76.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 75.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 75.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 75.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 75.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 75.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 74.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 74.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 74.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 74.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 74.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 73.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 73.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 73.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 73.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 72.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 72.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 72.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 72.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 71.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 71.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 71.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 70.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 70.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 69.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 69.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 69.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 68.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 68.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 68.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 67.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 67.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 66.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 64.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 64.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 63.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 63.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 62.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 61.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 60.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 60.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 60.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 59.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 58.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 54.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 54.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 53.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 52.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 51.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 49.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

54.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 54.5
FF:10158-103A5 76 years, female 54.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

63.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 63.3
Samples: 4

Max nTPM: 84.9
Min nTPM: 34.3
Sample A Female 75.9
Sample B Female 84.9
Sample C Male 57.9
Sample D Male 34.3
Midbrain
nTPM: 49.4
Samples: 4

Max nTPM: 65.3
Min nTPM: 42.2
Sample A Female 65.3
Sample B Female 46.3
Sample C Male 42.2
Sample D Male 43.7
Periaqueductal gray
nTPM: 50.0
Samples: 3

Max nTPM: 61.4
Min nTPM: 42.8
Sample B Female 45.8
Sample C Male 61.4
Sample D Male 42.8
Superior colliculi
nTPM: 50.1
Samples: 4

Max nTPM: 68.4
Min nTPM: 41.1
Sample A Female 68.4
Sample B Female 43.2
Sample C Male 47.8
Sample D Male 41.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

68.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 68.8
Samples: 4

Max nTPM: 72.1
Min nTPM: 64.8
Sample A Male 71.3
Sample B Male 67.1
Sample C Female 64.8
Sample D Female 72.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.4
73834104 Antisense, RP_050725_02_F02, Mouse strain C57BL/6J (56 days, male) 3.4
70813922 Antisense, RP_050725_02_F02, Mouse strain C57BL/6J (56 days, male) 2.2

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