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  • EPB41L1
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:88.2 nTPM
HPA Brain:283.8 nTPM
GTEx:88.2 nTPM
FANTOM5:142.4 Scaled Tags Per Million
Pig:180.0 nTPM
Mouse:126.4 nTPM
Allen mouse:10.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

283.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 245.1
2586 Male, age 75, left hemisphere 326.4
2666 Male, age 74, left hemisphere 280.0
2219 Male, age 76, both hemispheres 249.5
1870 Female, age 42, unknown 241.0
1833 Male, age 53, unknown 240.6
1827 Male, age 72, unknown 230.2
1830 Male, age 51, unknown 228.2
2828 Female, age 72, unknown 227.8
2411 Female, age 72, unknown 220.6
2019 Male, age 18, unknown 207.0
Dorsal raphe nucleus
nTPM: 265.4
2047 Male, age 72, unknown 333.2
1828 Male, age 53, unknown 285.0
2750 Male, age 76, both hemispheres 239.0
2298 Female, age 72, unknown 235.1
2016 Female, age 72, unknown 234.8
Inferior colliculus
nTPM: 257.3
2849 Male, age 72, unknown 287.0
1848 Female, age 42, unknown 273.6
1890 Male, age 53, unknown 243.4
2097 Female, age 72, unknown 225.0
Median raphe nucleus
nTPM: 269.6
2220 Male, age 76, midline 269.6
Periaquaductal grey, anterior
nTPM: 267.1
1947 Male, age 18, unknown 295.9
2502 Female, age 75, unknown 261.8
1795 Male, age 51, unknown 243.6
Periaquaductal grey, dorsal
nTPM: 213.7
1840 Male, age 53, unknown 255.7
1831 Male, age 72, unknown 204.0
2850 Male, age 76, both hemispheres 198.7
2464 Female, age 72, unknown 196.2
Periaquaductal grey, lateral
nTPM: 194.5
2053 Male, age 18, unknown 209.1
2140 Male, age 76, both hemispheres 198.6
2272 Male, age 74, both hemispheres 175.9
Pretectal area
nTPM: 201.1
2825 Male, age 18, unknown 254.0
2667 Female, age 75, unknown 236.4
2224 Female, age 72, unknown 231.0
2407 Male, age 75, both hemispheres 221.2
2316 Male, age 76, right hemisphere 211.9
2007 Male, age 72, unknown 196.6
1817 Female, age 42, unknown 180.3
1816 Male, age 51, unknown 175.5
1944 Female, age 72, unknown 174.5
1815 Male, age 53, unknown 170.0
2273 Male, age 74, both hemispheres 160.4
Red nucleus
nTPM: 240.5
2584 Male, age 75, left hemisphere 276.4
2769 Male, age 72, unknown 264.9
2823 Male, age 76, right hemisphere 259.1
2227 Male, age 72, unknown 254.0
1821 Female, age 72, unknown 249.3
2588 Male, age 74, left hemisphere 244.2
2725 Female, age 75, unknown 240.4
1954 Female, age 42, unknown 230.9
1904 Male, age 53, unknown 226.3
2503 Female, age 72, unknown 226.1
1865 Male, age 51, unknown 225.8
2785 Male, age 18, unknown 188.5
Substantia nigra
nTPM: 283.8
1916 Female, age 42, unknown 393.7
2665 Male, age 74, both hemispheres 312.8
2699 Male, age 18, unknown 302.6
1851 Male, age 51, unknown 297.3
1941 Male, age 53, unknown 295.9
2583 Male, age 75, right hemisphere 276.9
2241 Male, age 72, unknown 266.7
2409 Female, age 72, unknown 243.7
2590 Female, age 75, unknown 224.5
1889 Female, age 72, unknown 224.2
Superior colliculus
nTPM: 206.6
1895 Male, age 76, right hemisphere 264.2
1839 Male, age 51, unknown 258.3
2664 Male, age 75, both hemispheres 257.2
1796 Male, age 53, unknown 224.4
2668 Female, age 75, unknown 214.8
2587 Male, age 74, left hemisphere 204.3
2261 Male, age 18, unknown 182.3
2087 Female, age 72, unknown 166.0
1913 Female, age 42, unknown 153.1
1995 Male, age 72, unknown 141.4
Ventral tegmental area
nTPM: 271.6
1915 Female, age 42, unknown 315.0
1942 Male, age 51, unknown 278.9
2218 Male, age 76, both hemispheres 274.8
2410 Female, age 72, unknown 271.9
2223 Female, age 72, unknown 256.9
2021 Male, age 53, unknown 232.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

88.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 88.2
Samples: 139

Max nTPM: 202.2
Min nTPM: 32.7
Std nTPM: 33.6
Median nTPM: 81.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 202.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 194.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 178.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 175.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 148.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 148.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 147.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 147.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 147.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 144.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 142.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 142.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 142.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 141.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 138.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 129.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 128.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 126.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 126.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 123.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 123.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 123.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 122.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 121.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 121.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 120.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 119.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 117.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 117.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 114.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 113.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 111.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 111.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 107.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 107.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 107.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 106.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 106.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 106.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 105.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 103.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 103.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 103.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 102.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 100.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 100.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 99.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 98.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 98.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 96.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 96.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 95.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 94.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 93.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 90.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 90.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 87.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 87.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 86.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 85.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 84.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 83.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 83.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 82.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 82.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 82.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 82.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 81.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 81.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 81.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 80.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 80.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 79.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 78.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 78.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 77.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 77.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 76.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 75.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 75.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 75.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 74.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 74.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 74.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 74.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 74.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 73.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 73.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 72.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 72.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 70.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 70.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 70.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 68.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 68.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 67.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 66.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 66.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 66.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 65.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 65.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 65.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 64.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 63.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 62.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 62.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 61.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 61.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 61.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 58.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 57.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 57.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 57.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 57.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 56.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 56.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 56.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 54.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 54.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 54.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 53.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 53.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 53.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 52.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 52.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 52.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 52.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 51.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 48.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 47.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 43.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 42.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 41.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 41.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 40.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 40.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 37.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 36.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 32.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

142.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 142.4
FF:10158-103A5 76 years, female 142.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

180.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 169.2
Samples: 4

Max nTPM: 229.3
Min nTPM: 115.8
Sample A Female 210.1
Sample B Female 115.8
Sample C Male 229.3
Sample D Male 121.7
Midbrain
nTPM: 165.5
Samples: 4

Max nTPM: 213.4
Min nTPM: 122.9
Sample A Female 122.9
Sample B Female 148.2
Sample C Male 213.4
Sample D Male 177.6
Periaqueductal gray
nTPM: 126.1
Samples: 3

Max nTPM: 138.4
Min nTPM: 108.3
Sample B Female 131.7
Sample C Male 138.4
Sample D Male 108.3
Superior colliculi
nTPM: 180.0
Samples: 4

Max nTPM: 228.4
Min nTPM: 102.4
Sample A Female 179.1
Sample B Female 102.4
Sample C Male 228.4
Sample D Male 210.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

126.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 126.4
Samples: 4

Max nTPM: 129.3
Min nTPM: 122.1
Sample A Male 122.1
Sample B Male 125.1
Sample C Female 129.0
Sample D Female 129.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

10.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.0
74047777 Antisense, RP_051214_02_A02, Mouse strain C57BL/6J (56 days, male) 17.3
68203494 Antisense, RP_041208_01_D02, Mouse strain C57BL/6J (56 days, male) 12.6
70795892 Antisense, RP_050712_02_B09, Mouse strain C57BL/6J (56 days, male) 6.1
74750065 Antisense, RP_060220_05_F07, Mouse strain C57BL/6J (56 days, male) 4.0

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