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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:811.5 nTPM
HPA Brain:409.5 nTPM
GTEx:811.5 nTPM
FANTOM5:24.7 Scaled Tags Per Million
Pig:856.7 nTPM
Mouse:463.9 nTPM
Allen mouse:17.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

409.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 344.2
2586 Male, age 75, left hemisphere 452.4
2666 Male, age 74, left hemisphere 394.1
1870 Female, age 42, unknown 358.2
2411 Female, age 72, unknown 348.3
1827 Male, age 72, unknown 334.2
2219 Male, age 76, both hemispheres 330.4
1833 Male, age 53, unknown 323.5
1830 Male, age 51, unknown 311.7
2828 Female, age 72, unknown 302.4
2019 Male, age 18, unknown 286.8
Dorsal raphe nucleus
nTPM: 336.5
2298 Female, age 72, unknown 345.8
2750 Male, age 76, both hemispheres 342.8
2016 Female, age 72, unknown 335.8
1828 Male, age 53, unknown 329.5
2047 Male, age 72, unknown 328.8
Inferior colliculus
nTPM: 337.7
1890 Male, age 53, unknown 348.4
2849 Male, age 72, unknown 338.1
1848 Female, age 42, unknown 333.5
2097 Female, age 72, unknown 330.8
Median raphe nucleus
nTPM: 342.3
2220 Male, age 76, midline 342.3
Periaquaductal grey, anterior
nTPM: 339.6
2502 Female, age 75, unknown 360.6
1947 Male, age 18, unknown 345.9
1795 Male, age 51, unknown 312.3
Periaquaductal grey, dorsal
nTPM: 314.9
1840 Male, age 53, unknown 371.3
2464 Female, age 72, unknown 329.2
1831 Male, age 72, unknown 305.6
2850 Male, age 76, both hemispheres 253.4
Periaquaductal grey, lateral
nTPM: 269.1
2053 Male, age 18, unknown 320.4
2272 Male, age 74, both hemispheres 254.8
2140 Male, age 76, both hemispheres 232.1
Pretectal area
nTPM: 303.5
2825 Male, age 18, unknown 331.2
2407 Male, age 75, both hemispheres 328.6
1816 Male, age 51, unknown 311.7
2224 Female, age 72, unknown 310.0
1817 Female, age 42, unknown 309.1
2007 Male, age 72, unknown 308.2
1815 Male, age 53, unknown 307.0
1944 Female, age 72, unknown 306.5
2316 Male, age 76, right hemisphere 288.5
2667 Female, age 75, unknown 273.5
2273 Male, age 74, both hemispheres 264.2
Red nucleus
nTPM: 335.6
2584 Male, age 75, left hemisphere 389.3
2503 Female, age 72, unknown 385.0
1821 Female, age 72, unknown 378.0
1865 Male, age 51, unknown 366.4
2588 Male, age 74, left hemisphere 338.0
1904 Male, age 53, unknown 329.5
2227 Male, age 72, unknown 329.2
2769 Male, age 72, unknown 327.1
2725 Female, age 75, unknown 321.3
2785 Male, age 18, unknown 297.3
1954 Female, age 42, unknown 292.4
2823 Male, age 76, right hemisphere 273.8
Substantia nigra
nTPM: 409.5
2241 Male, age 72, unknown 482.1
1851 Male, age 51, unknown 455.2
1916 Female, age 42, unknown 451.4
2665 Male, age 74, both hemispheres 436.6
2699 Male, age 18, unknown 432.0
2409 Female, age 72, unknown 406.0
2590 Female, age 75, unknown 378.6
2583 Male, age 75, right hemisphere 370.7
1941 Male, age 53, unknown 350.1
1889 Female, age 72, unknown 332.3
Superior colliculus
nTPM: 325.8
2668 Female, age 75, unknown 376.8
2587 Male, age 74, left hemisphere 359.5
2664 Male, age 75, both hemispheres 352.3
1796 Male, age 53, unknown 332.8
1839 Male, age 51, unknown 325.6
1895 Male, age 76, right hemisphere 325.3
2261 Male, age 18, unknown 304.4
1913 Female, age 42, unknown 303.4
1995 Male, age 72, unknown 296.2
2087 Female, age 72, unknown 281.9
Ventral tegmental area
nTPM: 364.5
1915 Female, age 42, unknown 420.3
2223 Female, age 72, unknown 380.8
2021 Male, age 53, unknown 361.0
2410 Female, age 72, unknown 346.6
1942 Male, age 51, unknown 340.3
2218 Male, age 76, both hemispheres 337.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

811.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 811.5
Samples: 139

Max nTPM: 2056.9
Min nTPM: 441.9
Std nTPM: 237.0
Median nTPM: 769.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 2056.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1566.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1515.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1471.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1324.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1314.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1290.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1215.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1160.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1152.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1151.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1113.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1105.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1102.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1100.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1068.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1066.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1042.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1039.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1036.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1032.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1007.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1002.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 979.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 973.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 963.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 962.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 946.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 945.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 944.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 935.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 933.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 920.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 917.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 914.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 908.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 907.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 906.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 906.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 893.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 893.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 886.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 883.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 873.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 860.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 859.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 857.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 854.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 853.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 851.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 848.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 839.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 837.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 830.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 811.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 809.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 805.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 804.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 801.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 793.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 791.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 786.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 785.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 785.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 783.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 783.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 781.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 778.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 773.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 769.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 766.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 766.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 764.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 761.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 753.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 752.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 751.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 749.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 747.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 746.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 745.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 727.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 723.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 721.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 719.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 718.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 710.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 706.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 706.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 706.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 705.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 693.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 692.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 689.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 689.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 682.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 680.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 677.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 671.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 668.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 666.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 659.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 658.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 653.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 652.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 646.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 645.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 645.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 636.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 621.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 617.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 616.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 608.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 607.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 607.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 601.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 600.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 598.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 595.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 594.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 592.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 584.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 570.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 569.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 561.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 558.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 548.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 544.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 543.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 540.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 536.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 536.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 534.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 529.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 522.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 511.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 489.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 485.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 441.9
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

24.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 24.7
FF:10158-103A5 76 years, female 24.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

856.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 847.2
Samples: 4

Max nTPM: 1018.9
Min nTPM: 700.6
Sample A Female 1018.9
Sample B Female 915.1
Sample C Male 754.1
Sample D Male 700.6
Midbrain
nTPM: 824.2
Samples: 4

Max nTPM: 1045.2
Min nTPM: 669.8
Sample A Female 1045.2
Sample B Female 887.8
Sample C Male 693.9
Sample D Male 669.8
Periaqueductal gray
nTPM: 701.9
Samples: 3

Max nTPM: 733.4
Min nTPM: 649.4
Sample B Female 733.4
Sample C Male 723.0
Sample D Male 649.4
Superior colliculi
nTPM: 856.7
Samples: 4

Max nTPM: 979.9
Min nTPM: 764.5
Sample A Female 979.9
Sample B Female 911.3
Sample C Male 771.1
Sample D Male 764.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

463.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 463.9
Samples: 4

Max nTPM: 497.1
Min nTPM: 424.6
Sample A Male 497.1
Sample B Male 458.5
Sample C Female 424.6
Sample D Female 475.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

17.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 17.8
69818317 Antisense, RP_050510_04_H04, Mouse strain C57BL/6J (56 days, male) 17.8

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The Human Protein Atlas project is funded
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