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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
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VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:463.8 nTPM
HPA Brain:729.3 nTPM
GTEx:463.8 nTPM
FANTOM5:2002.3 Scaled Tags Per Million
Pig:1145.1 nTPM
Mouse:683.9 nTPM
Allen mouse:2.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

729.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 591.8
2411 Female, age 72, unknown 1101.6
2019 Male, age 18, unknown 823.1
1870 Female, age 42, unknown 796.8
1830 Male, age 51, unknown 761.7
1833 Male, age 53, unknown 643.5
2828 Female, age 72, unknown 557.4
1827 Male, age 72, unknown 394.6
2219 Male, age 76, both hemispheres 371.6
2666 Male, age 74, left hemisphere 256.2
2586 Male, age 75, left hemisphere 211.8
Dorsal raphe nucleus
nTPM: 521.1
2750 Male, age 76, both hemispheres 1078.4
2016 Female, age 72, unknown 475.7
1828 Male, age 53, unknown 419.2
2298 Female, age 72, unknown 358.1
2047 Male, age 72, unknown 273.9
Inferior colliculus
nTPM: 344.0
1848 Female, age 42, unknown 396.8
1890 Male, age 53, unknown 385.6
2097 Female, age 72, unknown 329.0
2849 Male, age 72, unknown 264.7
Median raphe nucleus
nTPM: 471.0
2220 Male, age 76, midline 471.0
Periaquaductal grey, anterior
nTPM: 284.7
2502 Female, age 75, unknown 320.4
1947 Male, age 18, unknown 303.3
1795 Male, age 51, unknown 230.4
Periaquaductal grey, dorsal
nTPM: 233.1
2464 Female, age 72, unknown 453.1
1831 Male, age 72, unknown 251.6
1840 Male, age 53, unknown 120.4
2850 Male, age 76, both hemispheres 107.4
Periaquaductal grey, lateral
nTPM: 304.4
2272 Male, age 74, both hemispheres 420.3
2053 Male, age 18, unknown 360.9
2140 Male, age 76, both hemispheres 131.9
Pretectal area
nTPM: 367.3
2316 Male, age 76, right hemisphere 529.9
2273 Male, age 74, both hemispheres 477.7
1815 Male, age 53, unknown 457.2
2407 Male, age 75, both hemispheres 410.6
2007 Male, age 72, unknown 382.7
1817 Female, age 42, unknown 371.4
2667 Female, age 75, unknown 367.9
2825 Male, age 18, unknown 337.7
2224 Female, age 72, unknown 317.8
1944 Female, age 72, unknown 221.2
1816 Male, age 51, unknown 166.5
Red nucleus
nTPM: 729.3
1821 Female, age 72, unknown 1033.9
1865 Male, age 51, unknown 906.5
1904 Male, age 53, unknown 856.2
2823 Male, age 76, right hemisphere 839.7
2769 Male, age 72, unknown 824.3
2227 Male, age 72, unknown 823.8
2785 Male, age 18, unknown 763.1
2503 Female, age 72, unknown 697.1
1954 Female, age 42, unknown 684.1
2588 Male, age 74, left hemisphere 497.0
2725 Female, age 75, unknown 461.6
2584 Male, age 75, left hemisphere 364.7
Substantia nigra
nTPM: 365.8
1851 Male, age 51, unknown 481.6
1889 Female, age 72, unknown 466.3
2590 Female, age 75, unknown 416.3
2409 Female, age 72, unknown 392.8
1941 Male, age 53, unknown 387.6
2241 Male, age 72, unknown 365.9
1916 Female, age 42, unknown 360.0
2583 Male, age 75, right hemisphere 349.1
2699 Male, age 18, unknown 260.1
2665 Male, age 74, both hemispheres 178.1
Superior colliculus
nTPM: 418.3
1913 Female, age 42, unknown 586.9
1895 Male, age 76, right hemisphere 585.5
2587 Male, age 74, left hemisphere 575.6
1995 Male, age 72, unknown 555.8
1839 Male, age 51, unknown 440.5
2668 Female, age 75, unknown 418.6
1796 Male, age 53, unknown 348.7
2087 Female, age 72, unknown 268.1
2261 Male, age 18, unknown 223.4
2664 Male, age 75, both hemispheres 180.1
Ventral tegmental area
nTPM: 571.2
2223 Female, age 72, unknown 1025.5
2410 Female, age 72, unknown 689.4
1942 Male, age 51, unknown 472.5
2021 Male, age 53, unknown 438.1
2218 Male, age 76, both hemispheres 411.0
1915 Female, age 42, unknown 391.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

463.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 463.8
Samples: 139

Max nTPM: 2326.6
Min nTPM: 129.9
Std nTPM: 308.6
Median nTPM: 381.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 2326.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1463.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1306.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1290.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1232.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1184.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1181.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1125.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 1038.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 893.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 886.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 876.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 814.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 812.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 811.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 808.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 799.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 777.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 763.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 735.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 714.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 708.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 671.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 643.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 640.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 636.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 613.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 606.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 601.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 600.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 593.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 585.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 567.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 557.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 554.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 544.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 537.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 527.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 526.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 526.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 525.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 517.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 516.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 495.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 485.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 478.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 477.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 459.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 459.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 449.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 448.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 446.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 444.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 441.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 441.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 436.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 426.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 420.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 420.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 406.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 405.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 398.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 394.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 387.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 387.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 387.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 385.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 384.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 382.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 381.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 380.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 376.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 375.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 372.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 372.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 372.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 369.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 364.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 361.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 359.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 354.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 352.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 351.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 345.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 340.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 331.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 330.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 323.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 323.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 313.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 311.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 309.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 308.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 299.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 296.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 295.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 294.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 293.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 291.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 288.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 286.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 285.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 283.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 272.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 265.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 262.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 260.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 254.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 245.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 244.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 243.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 242.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 238.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 238.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 229.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 226.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 222.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 220.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 219.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 217.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 210.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 209.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 207.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 203.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 198.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 193.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 182.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 179.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 177.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 175.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 175.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 168.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 158.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 157.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 139.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 136.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 135.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 135.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 129.9
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

2002.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 2002.3
FF:10158-103A5 76 years, female 2002.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1145.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 840.9
Samples: 4

Max nTPM: 1439.4
Min nTPM: 446.9
Sample A Female 884.7
Sample B Female 446.9
Sample C Male 592.7
Sample D Male 1439.4
Midbrain
nTPM: 1145.1
Samples: 4

Max nTPM: 2998.7
Min nTPM: 401.8
Sample A Female 2998.7
Sample B Female 761.6
Sample C Male 418.4
Sample D Male 401.8
Periaqueductal gray
nTPM: 474.8
Samples: 3

Max nTPM: 652.7
Min nTPM: 329.7
Sample B Female 652.7
Sample C Male 329.7
Sample D Male 442.1
Superior colliculi
nTPM: 657.4
Samples: 4

Max nTPM: 805.9
Min nTPM: 328.7
Sample A Female 805.9
Sample B Female 328.7
Sample C Male 714.2
Sample D Male 780.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

683.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 683.9
Samples: 4

Max nTPM: 723.2
Min nTPM: 629.5
Sample A Male 670.4
Sample B Male 629.5
Sample C Female 723.2
Sample D Female 712.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.8
68795444 Antisense, RP_041130_01_F08, Mouse strain C57BL/6J (56 days, male) 2.8

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


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