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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:180.3 nTPM
HPA Brain:152.2 nTPM
GTEx:180.3 nTPM
FANTOM5:440.7 Scaled Tags Per Million
Pig:280.0 nTPM
Mouse:812.6 nTPM
Allen mouse:25.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

152.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 132.5
1870 Female, age 42, unknown 167.0
2019 Male, age 18, unknown 153.9
2828 Female, age 72, unknown 143.1
1833 Male, age 53, unknown 142.7
2411 Female, age 72, unknown 136.5
1830 Male, age 51, unknown 134.2
2219 Male, age 76, both hemispheres 123.0
2586 Male, age 75, left hemisphere 119.6
1827 Male, age 72, unknown 119.4
2666 Male, age 74, left hemisphere 85.1
Dorsal raphe nucleus
nTPM: 152.2
2750 Male, age 76, both hemispheres 166.2
2298 Female, age 72, unknown 158.8
2047 Male, age 72, unknown 158.5
1828 Male, age 53, unknown 154.2
2016 Female, age 72, unknown 123.4
Inferior colliculus
nTPM: 135.1
1848 Female, age 42, unknown 143.1
2097 Female, age 72, unknown 137.3
2849 Male, age 72, unknown 135.6
1890 Male, age 53, unknown 124.6
Median raphe nucleus
nTPM: 131.8
2220 Male, age 76, midline 131.8
Periaquaductal grey, anterior
nTPM: 121.3
2502 Female, age 75, unknown 131.0
1947 Male, age 18, unknown 117.3
1795 Male, age 51, unknown 115.6
Periaquaductal grey, dorsal
nTPM: 113.6
1840 Male, age 53, unknown 115.7
2850 Male, age 76, both hemispheres 115.5
2464 Female, age 72, unknown 113.8
1831 Male, age 72, unknown 109.2
Periaquaductal grey, lateral
nTPM: 121.5
2272 Male, age 74, both hemispheres 156.7
2053 Male, age 18, unknown 117.8
2140 Male, age 76, both hemispheres 90.0
Pretectal area
nTPM: 145.1
2667 Female, age 75, unknown 183.6
1817 Female, age 42, unknown 167.3
2007 Male, age 72, unknown 155.5
2224 Female, age 72, unknown 153.6
2273 Male, age 74, both hemispheres 152.1
1944 Female, age 72, unknown 146.9
1815 Male, age 53, unknown 139.0
1816 Male, age 51, unknown 134.3
2825 Male, age 18, unknown 122.7
2316 Male, age 76, right hemisphere 121.4
2407 Male, age 75, both hemispheres 119.7
Red nucleus
nTPM: 148.9
2823 Male, age 76, right hemisphere 184.3
1821 Female, age 72, unknown 167.4
1904 Male, age 53, unknown 160.5
1954 Female, age 42, unknown 157.3
2769 Male, age 72, unknown 157.2
1865 Male, age 51, unknown 155.9
2785 Male, age 18, unknown 154.8
2227 Male, age 72, unknown 152.2
2503 Female, age 72, unknown 151.6
2725 Female, age 75, unknown 129.0
2584 Male, age 75, left hemisphere 118.7
2588 Male, age 74, left hemisphere 97.4
Substantia nigra
nTPM: 116.4
1889 Female, age 72, unknown 155.6
1851 Male, age 51, unknown 134.0
1916 Female, age 42, unknown 133.6
1941 Male, age 53, unknown 126.6
2699 Male, age 18, unknown 124.2
2409 Female, age 72, unknown 107.0
2583 Male, age 75, right hemisphere 101.1
2241 Male, age 72, unknown 94.1
2590 Female, age 75, unknown 94.0
2665 Male, age 74, both hemispheres 94.0
Superior colliculus
nTPM: 134.1
1895 Male, age 76, right hemisphere 152.2
1913 Female, age 42, unknown 150.5
1995 Male, age 72, unknown 146.6
2587 Male, age 74, left hemisphere 146.0
2668 Female, age 75, unknown 134.1
2087 Female, age 72, unknown 132.5
1839 Male, age 51, unknown 131.0
1796 Male, age 53, unknown 125.9
2261 Male, age 18, unknown 120.6
2664 Male, age 75, both hemispheres 101.3
Ventral tegmental area
nTPM: 136.2
2223 Female, age 72, unknown 172.8
2410 Female, age 72, unknown 144.3
2218 Male, age 76, both hemispheres 135.1
1915 Female, age 42, unknown 126.9
1942 Male, age 51, unknown 121.0
2021 Male, age 53, unknown 117.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

180.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 180.3
Samples: 139

Max nTPM: 385.7
Min nTPM: 98.5
Std nTPM: 50.7
Median nTPM: 169.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 385.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 326.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 312.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 298.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 298.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 293.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 293.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 273.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 273.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 272.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 269.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 267.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 257.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 256.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 252.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 250.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 248.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 246.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 242.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 238.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 236.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 229.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 229.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 228.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 224.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 220.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 218.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 217.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 217.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 214.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 212.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 208.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 208.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 207.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 206.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 200.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 200.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 200.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 198.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 196.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 196.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 192.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 191.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 189.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 188.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 187.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 187.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 186.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 186.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 185.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 185.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 184.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 183.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 183.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 182.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 182.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 182.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 180.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 176.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 175.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 174.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 173.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 172.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 172.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 172.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 171.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 171.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 170.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 170.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 169.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 168.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 168.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 168.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 167.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 165.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 164.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 163.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 163.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 163.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 158.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 158.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 157.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 155.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 155.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 153.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 153.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 153.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 153.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 153.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 151.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 150.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 149.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 148.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 148.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 148.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 147.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 146.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 146.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 145.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 144.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 143.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 143.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 142.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 142.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 141.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 140.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 140.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 140.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 138.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 138.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 138.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 138.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 137.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 136.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 135.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 135.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 135.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 134.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 133.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 132.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 132.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 131.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 131.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 129.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 128.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 128.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 127.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 126.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 126.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 125.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 125.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 124.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 124.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 123.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 122.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 120.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 117.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 110.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 98.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

440.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 440.7
FF:10158-103A5 76 years, female 440.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

280.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 225.6
Samples: 4

Max nTPM: 261.1
Min nTPM: 140.3
Sample A Female 260.8
Sample B Female 140.3
Sample C Male 240.0
Sample D Male 261.1
Midbrain
nTPM: 280.0
Samples: 4

Max nTPM: 455.2
Min nTPM: 211.2
Sample A Female 455.2
Sample B Female 211.2
Sample C Male 225.2
Sample D Male 228.5
Periaqueductal gray
nTPM: 203.4
Samples: 3

Max nTPM: 227.1
Min nTPM: 187.6
Sample B Female 195.4
Sample C Male 227.1
Sample D Male 187.6
Superior colliculi
nTPM: 246.9
Samples: 4

Max nTPM: 299.6
Min nTPM: 144.7
Sample A Female 299.6
Sample B Female 144.7
Sample C Male 269.7
Sample D Male 273.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

812.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 812.6
Samples: 4

Max nTPM: 845.9
Min nTPM: 787.1
Sample A Male 803.1
Sample B Male 787.1
Sample C Female 814.2
Sample D Female 845.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

25.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 25.2
544902 Antisense, RP_040420_01_H11, Mouse strain C57BL/6J (56 days, male) 26.5
75694901 Antisense, RP_060518_04_A09, Mouse strain C57BL/6J (56 days, male) 23.8

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