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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
High
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
118.9
nTPM
HPA:
70.1
nTPM
GTEx:
118.9
nTPM
FANTOM5:
246.6
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA001209
Cholangiocytes
High
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
70.1
Female, age 60
Liver sample 21 nTPM: 81.3
Male, age 54
Liver sample 23 nTPM: 109.8
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 83.4
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 29
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 32.3
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 42.7
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 66.3
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 108.8
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 65.4
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 81.6
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
118.9
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 118.9
Samples: 226
Max nTPM: 242.1
Min nTPM: 39.3
Std nTPM: 33.2
Median nTPM: 115.3
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
242.1
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
194.4
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
190.7
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
188.3
GTEX-13113-1326-SM-5GCOI
60-69 years, female
187.8
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
185.5
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
185.2
GTEX-17F96-1226-SM-79OK2
70-79 years, male
182.9
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
182.6
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
182.5
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
176.3
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
174.7
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
174.0
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
173.5
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
173.3
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
173.1
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
173.1
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
172.8
GTEX-14PHX-0526-SM-664NW
50-59 years, male
172.6
GTEX-REY6-1226-SM-48FDR
60-69 years, male
172.3
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
169.2
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
168.7
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
165.8
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
165.0
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
164.8
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
164.7
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
164.1
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
163.6
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
163.0
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
163.0
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
159.2
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
158.6
GTEX-X261-1726-SM-4PQYT
50-59 years, male
158.2
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
155.0
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
152.8
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
152.3
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
151.2
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
150.4
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
150.3
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
150.0
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
149.8
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
147.8
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
147.8
GTEX-1B932-1426-SM-793AN
40-49 years, female
147.6
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
147.4
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
146.9
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
146.7
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
145.9
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
145.3
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
145.1
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
144.5
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
144.4
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
144.1
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
143.7
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
143.0
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
142.6
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
142.3
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
142.2
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
141.9
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
141.0
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
140.5
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
139.0
GTEX-14JG1-1626-SM-664NH
40-49 years, male
138.5
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
138.5
GTEX-RN64-1826-SM-48FDV
50-59 years, male
138.1
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
137.0
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
136.8
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
136.4
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
135.7
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
135.7
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
135.1
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
134.8
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
133.5
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
133.4
GTEX-18A7A-1526-SM-72D69
50-59 years, female
132.8
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
131.6
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
130.4
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
130.4
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
129.8
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
129.7
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
129.4
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
129.1
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
129.0
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
128.3
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
127.7
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
127.7
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
126.8
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
126.7
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
125.8
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
125.0
GTEX-12696-0826-SM-5EGGE
60-69 years, male
124.9
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
124.8
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
124.7
GTEX-144GL-1426-SM-79OMA
50-59 years, male
124.3
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
124.0
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
122.7
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
122.3
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
122.0
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
121.8
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
121.6
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
121.4
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
119.9
GTEX-RU72-1426-SM-46MUF
50-59 years, female
119.8
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
119.0
GTEX-1B933-1226-SM-731DW
50-59 years, female
118.7
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
118.5
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
118.1
GTEX-11ZUS-2526-SM-59872
30-39 years, male
117.6
GTEX-14XAO-0226-SM-68728
60-69 years, female
117.5
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
117.2
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
117.0
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
117.0
GTEX-R53T-0326-SM-48FEC
50-59 years, female
115.4
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
115.3
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
115.3
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
115.2
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
114.5
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
114.3
GTEX-13112-1426-SM-5EGH8
50-59 years, male
114.0
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
113.9
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
111.9
GTEX-14E7W-1526-SM-6871X
70-79 years, male
111.6
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
111.0
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
110.7
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
109.4
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
109.2
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
109.1
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
109.1
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
109.1
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
108.8
GTEX-P78B-1326-SM-3P611
40-49 years, female
108.6
GTEX-YECK-1926-SM-4W21H
60-69 years, male
108.4
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
108.2
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
107.5
GTEX-18465-1626-SM-7LG6N
50-59 years, male
107.2
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
107.2
GTEX-S33H-1626-SM-4AD68
30-39 years, male
106.8
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
106.1
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
105.7
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
105.1
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
104.8
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
104.6
GTEX-17HHE-0126-SM-79398
50-59 years, male
104.5
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
103.5
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
103.2
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
103.1
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
102.0
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
100.7
GTEX-QESD-2026-SM-447BI
20-29 years, male
100.6
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
100.0
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
99.6
GTEX-18A66-2026-SM-7189C
60-69 years, male
97.6
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
97.1
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
96.9
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
96.6
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
96.5
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
96.3
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
96.3
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
96.2
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
96.1
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
96.0
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
95.6
GTEX-O5YV-0726-SM-EV798
60-69 years, female
95.1
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
94.8
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
94.4
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
94.1
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
94.0
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
94.0
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
93.8
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
93.6
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
93.4
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
93.3
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
92.8
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
92.1
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
92.1
GTEX-14PJO-1726-SM-68719
60-69 years, male
91.8
GTEX-QEL4-1226-SM-447A4
50-59 years, male
91.7
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
91.6
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
91.4
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
91.0
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
90.6
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
89.7
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
89.0
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
88.8
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
88.3
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
88.3
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
87.2
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
86.4
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
86.1
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
85.0
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
84.5
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
84.4
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
84.3
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
84.2
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
84.0
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
83.9
GTEX-Q734-0326-SM-48U15
40-49 years, female
83.8
GTEX-1399T-0826-SM-5IFES
60-69 years, male
83.5
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
82.5
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
82.4
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
82.3
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
81.3
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
81.0
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
80.5
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
80.0
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
79.1
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
79.0
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
78.8
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
78.0
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
77.9
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
77.0
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
74.6
GTEX-11GSP-0626-SM-5986T
60-69 years, female
72.7
GTEX-S32W-1926-SM-4AD63
50-59 years, female
72.6
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
71.5
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
70.0
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
68.8
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
68.6
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
68.4
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
67.2
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
62.4
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
57.5
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
55.9
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
54.6
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
44.9
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
39.3
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
