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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:149.2 nTPM
HPA Brain:107.8 nTPM
GTEx:149.2 nTPM
FANTOM5:155.6 Scaled Tags Per Million
Pig:88.1 nTPM
Mouse:80.7 nTPM
Allen mouse:7.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

107.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 107.0
2666 Male, age 74, left hemisphere 124.9
1833 Male, age 53, unknown 114.9
1827 Male, age 72, unknown 113.9
1830 Male, age 51, unknown 111.3
2586 Male, age 75, left hemisphere 110.7
1870 Female, age 42, unknown 102.6
2828 Female, age 72, unknown 102.4
2219 Male, age 76, both hemispheres 101.0
2019 Male, age 18, unknown 100.8
2411 Female, age 72, unknown 87.9
Dorsal raphe nucleus
nTPM: 91.7
1828 Male, age 53, unknown 101.8
2750 Male, age 76, both hemispheres 98.4
2016 Female, age 72, unknown 95.9
2047 Male, age 72, unknown 82.0
2298 Female, age 72, unknown 80.3
Inferior colliculus
nTPM: 98.8
2849 Male, age 72, unknown 116.3
1890 Male, age 53, unknown 98.2
2097 Female, age 72, unknown 92.1
1848 Female, age 42, unknown 88.7
Median raphe nucleus
nTPM: 100.4
2220 Male, age 76, midline 100.4
Periaquaductal grey, anterior
nTPM: 94.1
1947 Male, age 18, unknown 98.9
1795 Male, age 51, unknown 92.2
2502 Female, age 75, unknown 91.2
Periaquaductal grey, dorsal
nTPM: 103.3
2850 Male, age 76, both hemispheres 113.6
1831 Male, age 72, unknown 109.8
2464 Female, age 72, unknown 98.2
1840 Male, age 53, unknown 91.7
Periaquaductal grey, lateral
nTPM: 99.0
2140 Male, age 76, both hemispheres 106.4
2272 Male, age 74, both hemispheres 101.2
2053 Male, age 18, unknown 89.4
Pretectal area
nTPM: 102.7
1815 Male, age 53, unknown 118.3
2407 Male, age 75, both hemispheres 117.7
2316 Male, age 76, right hemisphere 108.7
2667 Female, age 75, unknown 107.8
2825 Male, age 18, unknown 107.2
1816 Male, age 51, unknown 106.4
1817 Female, age 42, unknown 98.4
2273 Male, age 74, both hemispheres 94.0
2007 Male, age 72, unknown 93.0
2224 Female, age 72, unknown 89.5
1944 Female, age 72, unknown 89.0
Red nucleus
nTPM: 107.8
2823 Male, age 76, right hemisphere 119.7
2584 Male, age 75, left hemisphere 119.3
2588 Male, age 74, left hemisphere 118.5
2725 Female, age 75, unknown 116.2
2769 Male, age 72, unknown 110.9
2227 Male, age 72, unknown 106.6
1821 Female, age 72, unknown 103.7
2503 Female, age 72, unknown 103.4
1865 Male, age 51, unknown 102.5
1904 Male, age 53, unknown 101.8
1954 Female, age 42, unknown 96.7
2785 Male, age 18, unknown 94.2
Substantia nigra
nTPM: 103.7
2699 Male, age 18, unknown 126.7
2665 Male, age 74, both hemispheres 121.7
1916 Female, age 42, unknown 111.8
1851 Male, age 51, unknown 102.9
2583 Male, age 75, right hemisphere 102.6
1941 Male, age 53, unknown 97.4
2590 Female, age 75, unknown 97.2
2409 Female, age 72, unknown 93.7
1889 Female, age 72, unknown 91.4
2241 Male, age 72, unknown 91.4
Superior colliculus
nTPM: 102.1
2664 Male, age 75, both hemispheres 125.7
1913 Female, age 42, unknown 113.6
1839 Male, age 51, unknown 106.1
1895 Male, age 76, right hemisphere 103.0
1995 Male, age 72, unknown 101.5
2261 Male, age 18, unknown 99.7
2668 Female, age 75, unknown 97.4
2087 Female, age 72, unknown 96.8
1796 Male, age 53, unknown 88.4
2587 Male, age 74, left hemisphere 88.4
Ventral tegmental area
nTPM: 95.6
1915 Female, age 42, unknown 102.3
2218 Male, age 76, both hemispheres 101.7
2021 Male, age 53, unknown 98.8
2223 Female, age 72, unknown 98.3
1942 Male, age 51, unknown 89.9
2410 Female, age 72, unknown 82.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

149.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 149.2
Samples: 139

Max nTPM: 241.6
Min nTPM: 82.2
Std nTPM: 28.3
Median nTPM: 145.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 241.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 229.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 227.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 211.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 205.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 205.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 201.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 198.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 194.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 191.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 191.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 188.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 187.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 187.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 186.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 185.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 182.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 182.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 182.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 178.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 176.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 176.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 176.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 175.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 174.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 174.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 172.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 169.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 168.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 168.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 166.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 166.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 166.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 166.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 165.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 165.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 164.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 163.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 163.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 162.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 161.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 161.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 161.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 161.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 161.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 160.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 158.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 158.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 157.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 157.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 155.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 155.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 154.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 154.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 154.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 153.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 152.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 152.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 151.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 151.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 151.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 151.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 151.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 150.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 149.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 149.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 149.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 148.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 148.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 145.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 145.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 144.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 144.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 144.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 144.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 144.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 143.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 143.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 143.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 142.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 141.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 141.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 139.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 139.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 139.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 138.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 138.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 138.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 138.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 137.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 135.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 134.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 132.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 132.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 131.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 131.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 131.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 131.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 131.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 131.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 130.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 130.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 130.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 129.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 129.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 129.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 129.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 129.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 128.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 128.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 126.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 126.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 126.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 125.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 124.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 123.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 123.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 122.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 122.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 122.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 120.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 120.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 120.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 118.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 118.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 117.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 116.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 114.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 113.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 111.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 109.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 108.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 107.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 100.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 99.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 96.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 93.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 90.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 82.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

155.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 155.6
FF:10158-103A5 76 years, female 155.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

88.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 88.2
Samples: 4

Max nTPM: 101.6
Min nTPM: 78.9
Sample A Female 78.9
Sample B Female 83.1
Sample C Male 89.0
Sample D Male 101.6
Midbrain
nTPM: 79.4
Samples: 4

Max nTPM: 90.4
Min nTPM: 68.3
Sample A Female 72.4
Sample B Female 86.4
Sample C Male 68.3
Sample D Male 90.4
Periaqueductal gray
nTPM: 79.1
Samples: 3

Max nTPM: 79.8
Min nTPM: 78.5
Sample B Female 78.9
Sample C Male 78.5
Sample D Male 79.8
Superior colliculi
nTPM: 79.2
Samples: 4

Max nTPM: 92.0
Min nTPM: 70.3
Sample A Female 80.3
Sample B Female 70.3
Sample C Male 74.1
Sample D Male 92.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

80.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 80.7
Samples: 4

Max nTPM: 91.5
Min nTPM: 73.9
Sample A Male 91.5
Sample B Male 81.3
Sample C Female 76.0
Sample D Female 73.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

7.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.1
74431266 Antisense, RP_060207_01_F12, Mouse strain C57BL/6J (56 days, male) 12.0
70919579 Antisense, RP_050713_01_F03, Mouse strain C57BL/6J (56 days, male) 2.1

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