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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
High
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
265.1
nTPM
HPA:
265.1
nTPM
GTEx:
100.2
nTPM
FANTOM5:
293.6
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA001550
Antibody CAB010102
Cholangiocytes
Medium
High
Hepatocytes
Medium
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
265.1
Female, age 60
Liver sample 21 nTPM: 123.4
Male, age 54
Liver sample 23 nTPM: 261.8
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 253.8
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 197.6
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 396.9
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 227.5
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 213.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 366.9
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 334.6
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 275.4
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
100.2
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 100.2
Samples: 226
Max nTPM: 281.6
Min nTPM: 20.4
Std nTPM: 46.4
Median nTPM: 95.8
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
281.6
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
261.9
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
257.4
GTEX-17F96-1226-SM-79OK2
70-79 years, male
225.8
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
220.4
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
208.5
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
203.3
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
195.7
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
192.7
GTEX-18A7A-1526-SM-72D69
50-59 years, female
189.1
GTEX-14JG1-1626-SM-664NH
40-49 years, male
185.1
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
176.3
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
176.1
GTEX-R53T-0326-SM-48FEC
50-59 years, female
174.8
GTEX-QESD-2026-SM-447BI
20-29 years, male
172.9
GTEX-17HHE-0126-SM-79398
50-59 years, male
171.9
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
170.3
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
169.8
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
168.2
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
166.9
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
164.6
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
162.7
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
160.5
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
157.3
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
155.1
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
155.1
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
153.5
GTEX-14E7W-1526-SM-6871X
70-79 years, male
152.8
GTEX-X261-1726-SM-4PQYT
50-59 years, male
152.5
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
151.8
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
148.3
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
148.0
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
147.0
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
146.7
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
145.9
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
145.6
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
145.4
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
144.1
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
140.8
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
138.1
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
137.2
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
135.9
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
135.6
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
135.1
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
134.4
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
132.6
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
132.5
GTEX-13112-1426-SM-5EGH8
50-59 years, male
130.7
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
130.1
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
129.5
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
129.3
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
128.3
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
127.7
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
127.5
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
127.0
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
126.6
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
126.2
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
125.3
GTEX-14PHX-0526-SM-664NW
50-59 years, male
124.9
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
124.9
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
124.2
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
124.0
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
123.1
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
122.2
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
122.0
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
121.6
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
120.3
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
118.5
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
117.7
GTEX-18465-1626-SM-7LG6N
50-59 years, male
116.8
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
115.9
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
115.5
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
114.8
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
113.6
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
113.3
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
113.1
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
112.9
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
112.8
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
112.5
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
112.4
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
112.3
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
112.2
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
111.4
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
110.6
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
110.2
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
110.1
GTEX-144GL-1426-SM-79OMA
50-59 years, male
109.6
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
108.3
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
108.2
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
107.5
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
106.9
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
106.4
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
105.9
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
105.0
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
105.0
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
104.7
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
104.5
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
103.7
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
103.5
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
103.1
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
102.9
GTEX-YECK-1926-SM-4W21H
60-69 years, male
102.8
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
102.3
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
100.9
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
100.9
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
100.5
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
99.7
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
97.7
GTEX-1B933-1226-SM-731DW
50-59 years, female
97.2
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
97.0
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
96.9
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
96.4
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
96.2
GTEX-11GSP-0626-SM-5986T
60-69 years, female
95.5
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
95.0
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
94.9
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
94.1
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
94.1
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
93.3
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
93.1
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
92.5
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
92.5
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
92.4
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
92.3
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
91.5
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
91.4
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
90.5
GTEX-P78B-1326-SM-3P611
40-49 years, female
90.2
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
90.1
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
90.0
GTEX-1399T-0826-SM-5IFES
60-69 years, male
89.9
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
89.9
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
89.6
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
87.8
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
87.2
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
86.3
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
85.7
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
85.5
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
84.8
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
82.7
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
82.4
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
81.7
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
81.4
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
81.1
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
81.0
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
81.0
GTEX-11ZUS-2526-SM-59872
30-39 years, male
80.6
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
79.7
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
78.1
GTEX-RU72-1426-SM-46MUF
50-59 years, female
77.7
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
77.3
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
76.4
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
76.2
GTEX-12696-0826-SM-5EGGE
60-69 years, male
75.5
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
75.4
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
74.1
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
74.1
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
74.0
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
73.6
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
72.3
GTEX-RN64-1826-SM-48FDV
50-59 years, male
72.2
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
71.5
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
69.4
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
69.3
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
68.5
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
68.2
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
67.7
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
67.2
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
67.0
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
67.0
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
66.0
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
64.3
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
63.1
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
63.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
62.4
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
60.4
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
60.2
GTEX-18A66-2026-SM-7189C
60-69 years, male
59.5
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
58.8
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
58.3
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
57.8
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
57.5
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
57.4
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
56.8
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
55.4
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
55.1
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
54.8
GTEX-REY6-1226-SM-48FDR
60-69 years, male
54.6
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
53.7
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
53.5
GTEX-13113-1326-SM-5GCOI
60-69 years, female
52.9
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
52.3
GTEX-QEL4-1226-SM-447A4
50-59 years, male
51.5
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
51.4
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
50.9
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
50.1
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
48.2
GTEX-Q734-0326-SM-48U15
40-49 years, female
47.5
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
47.5
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
46.5
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
44.3
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
43.9
GTEX-S33H-1626-SM-4AD68
30-39 years, male
42.9
GTEX-14XAO-0226-SM-68728
60-69 years, female
42.1
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
40.7
GTEX-S32W-1926-SM-4AD63
50-59 years, female
39.6
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
38.9
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
38.7
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
38.2
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
38.0
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
38.0
GTEX-1B932-1426-SM-793AN
40-49 years, female
37.8
GTEX-O5YV-0726-SM-EV798
60-69 years, female
37.3
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
36.9
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
35.8
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
35.4
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
35.2
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
34.4
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
33.8
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
32.7
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
32.2
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
30.9
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
27.5
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
24.3
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
21.7
GTEX-14PJO-1726-SM-68719
60-69 years, male
20.4
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
