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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:340.6 nTPM
HPA Brain:918.4 nTPM
GTEx:340.6 nTPM
FANTOM5:1146.1 Scaled Tags Per Million
Pig:250.4 nTPM
Mouse:141.6 nTPM
Allen mouse:7.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

918.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 615.1
2019 Male, age 18, unknown 796.6
1830 Male, age 51, unknown 777.3
1833 Male, age 53, unknown 710.1
1870 Female, age 42, unknown 665.6
2411 Female, age 72, unknown 651.6
2828 Female, age 72, unknown 604.0
2666 Male, age 74, left hemisphere 601.0
2586 Male, age 75, left hemisphere 583.4
1827 Male, age 72, unknown 407.3
2219 Male, age 76, both hemispheres 354.2
Dorsal raphe nucleus
nTPM: 443.9
2750 Male, age 76, both hemispheres 851.9
2016 Female, age 72, unknown 404.7
1828 Male, age 53, unknown 395.9
2047 Male, age 72, unknown 311.0
2298 Female, age 72, unknown 256.2
Inferior colliculus
nTPM: 364.7
1890 Male, age 53, unknown 409.7
2849 Male, age 72, unknown 399.1
1848 Female, age 42, unknown 392.4
2097 Female, age 72, unknown 257.7
Median raphe nucleus
nTPM: 483.7
2220 Male, age 76, midline 483.7
Periaquaductal grey, anterior
nTPM: 358.4
2502 Female, age 75, unknown 455.1
1947 Male, age 18, unknown 323.2
1795 Male, age 51, unknown 296.9
Periaquaductal grey, dorsal
nTPM: 285.2
2464 Female, age 72, unknown 413.0
1831 Male, age 72, unknown 303.1
2850 Male, age 76, both hemispheres 221.9
1840 Male, age 53, unknown 202.8
Periaquaductal grey, lateral
nTPM: 306.8
2272 Male, age 74, both hemispheres 398.3
2053 Male, age 18, unknown 317.3
2140 Male, age 76, both hemispheres 204.7
Pretectal area
nTPM: 413.3
1815 Male, age 53, unknown 578.3
2007 Male, age 72, unknown 563.3
1817 Female, age 42, unknown 529.3
2316 Male, age 76, right hemisphere 490.2
2407 Male, age 75, both hemispheres 455.8
2825 Male, age 18, unknown 382.2
1944 Female, age 72, unknown 329.7
1816 Male, age 51, unknown 321.5
2667 Female, age 75, unknown 317.0
2273 Male, age 74, both hemispheres 296.7
2224 Female, age 72, unknown 282.4
Red nucleus
nTPM: 918.4
2823 Male, age 76, right hemisphere 1124.4
1865 Male, age 51, unknown 1045.1
1904 Male, age 53, unknown 1029.2
2785 Male, age 18, unknown 1006.4
2769 Male, age 72, unknown 966.6
2588 Male, age 74, left hemisphere 947.8
2503 Female, age 72, unknown 934.2
1821 Female, age 72, unknown 921.6
2227 Male, age 72, unknown 908.6
1954 Female, age 42, unknown 779.8
2584 Male, age 75, left hemisphere 697.3
2725 Female, age 75, unknown 660.1
Substantia nigra
nTPM: 469.9
2590 Female, age 75, unknown 598.9
1889 Female, age 72, unknown 570.7
2583 Male, age 75, right hemisphere 527.8
1851 Male, age 51, unknown 524.5
2409 Female, age 72, unknown 500.6
2699 Male, age 18, unknown 461.0
2665 Male, age 74, both hemispheres 429.6
1941 Male, age 53, unknown 380.5
1916 Female, age 42, unknown 367.0
2241 Male, age 72, unknown 338.9
Superior colliculus
nTPM: 488.6
1913 Female, age 42, unknown 672.6
1995 Male, age 72, unknown 669.4
2587 Male, age 74, left hemisphere 570.0
1839 Male, age 51, unknown 502.2
1895 Male, age 76, right hemisphere 500.8
2668 Female, age 75, unknown 492.1
1796 Male, age 53, unknown 407.2
2087 Female, age 72, unknown 369.2
2664 Male, age 75, both hemispheres 359.6
2261 Male, age 18, unknown 342.3
Ventral tegmental area
nTPM: 540.0
2223 Female, age 72, unknown 766.2
2410 Female, age 72, unknown 685.7
2218 Male, age 76, both hemispheres 501.7
2021 Male, age 53, unknown 460.4
1942 Male, age 51, unknown 429.8
1915 Female, age 42, unknown 396.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

340.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 340.6
Samples: 139

Max nTPM: 846.6
Min nTPM: 111.4
Std nTPM: 140.9
Median nTPM: 311.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 846.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 764.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 719.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 647.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 629.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 612.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 611.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 608.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 597.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 582.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 581.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 571.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 567.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 563.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 559.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 559.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 559.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 540.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 510.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 503.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 477.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 474.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 464.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 459.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 448.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 447.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 442.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 440.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 437.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 436.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 435.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 428.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 423.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 421.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 420.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 418.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 418.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 418.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 415.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 402.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 401.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 386.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 384.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 376.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 369.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 365.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 364.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 361.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 359.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 359.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 356.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 356.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 355.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 353.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 351.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 350.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 349.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 333.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 332.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 332.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 331.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 328.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 328.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 327.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 326.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 326.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 317.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 316.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 316.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 311.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 310.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 310.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 306.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 305.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 304.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 290.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 290.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 289.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 289.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 288.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 286.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 285.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 284.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 283.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 282.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 281.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 281.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 276.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 272.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 272.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 271.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 270.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 267.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 265.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 264.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 263.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 261.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 260.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 260.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 254.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 254.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 252.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 249.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 245.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 244.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 244.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 238.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 236.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 234.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 234.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 233.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 224.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 223.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 221.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 217.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 214.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 208.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 206.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 191.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 190.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 188.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 187.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 183.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 183.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 181.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 178.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 177.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 176.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 172.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 171.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 170.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 167.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 164.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 149.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 137.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 120.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 114.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 114.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 111.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1146.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1146.1
FF:10158-103A5 76 years, female 1146.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

250.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 224.8
Samples: 4

Max nTPM: 295.4
Min nTPM: 172.5
Sample A Female 250.1
Sample B Female 181.0
Sample C Male 172.5
Sample D Male 295.4
Midbrain
nTPM: 250.4
Samples: 4

Max nTPM: 573.5
Min nTPM: 110.0
Sample A Female 573.5
Sample B Female 193.7
Sample C Male 124.3
Sample D Male 110.0
Periaqueductal gray
nTPM: 145.3
Samples: 3

Max nTPM: 174.8
Min nTPM: 120.2
Sample B Female 174.8
Sample C Male 120.2
Sample D Male 141.0
Superior colliculi
nTPM: 202.3
Samples: 4

Max nTPM: 242.9
Min nTPM: 182.7
Sample A Female 242.9
Sample B Female 189.5
Sample C Male 182.7
Sample D Male 194.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

141.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 141.6
Samples: 4

Max nTPM: 142.9
Min nTPM: 140.3
Sample A Male 141.5
Sample B Male 142.9
Sample C Female 140.3
Sample D Female 141.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

7.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.6
70429303 Antisense, RP_050614_01_D08, Mouse strain C57BL/6J (56 days, male) 7.6

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