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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:307.0 nTPM
HPA Brain:134.6 nTPM
GTEx:307.0 nTPM
FANTOM5:74.7 Scaled Tags Per Million
Pig:64.6 nTPM
Mouse:115.8 nTPM
Allen mouse:0.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

134.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 130.7
2586 Male, age 75, left hemisphere 178.3
2666 Male, age 74, left hemisphere 142.7
1830 Male, age 51, unknown 136.4
2019 Male, age 18, unknown 135.1
2828 Female, age 72, unknown 134.5
1833 Male, age 53, unknown 120.3
2411 Female, age 72, unknown 119.1
1827 Male, age 72, unknown 116.9
1870 Female, age 42, unknown 116.5
2219 Male, age 76, both hemispheres 107.4
Dorsal raphe nucleus
nTPM: 119.0
2750 Male, age 76, both hemispheres 121.7
1828 Male, age 53, unknown 121.5
2047 Male, age 72, unknown 121.1
2016 Female, age 72, unknown 118.3
2298 Female, age 72, unknown 112.2
Inferior colliculus
nTPM: 110.3
2849 Male, age 72, unknown 118.5
1890 Male, age 53, unknown 114.4
1848 Female, age 42, unknown 108.5
2097 Female, age 72, unknown 99.8
Median raphe nucleus
nTPM: 110.8
2220 Male, age 76, midline 110.8
Periaquaductal grey, anterior
nTPM: 120.6
2502 Female, age 75, unknown 124.0
1795 Male, age 51, unknown 119.8
1947 Male, age 18, unknown 118.0
Periaquaductal grey, dorsal
nTPM: 111.5
2850 Male, age 76, both hemispheres 114.4
2464 Female, age 72, unknown 113.5
1831 Male, age 72, unknown 111.7
1840 Male, age 53, unknown 106.5
Periaquaductal grey, lateral
nTPM: 117.9
2140 Male, age 76, both hemispheres 130.3
2272 Male, age 74, both hemispheres 111.8
2053 Male, age 18, unknown 111.6
Pretectal area
nTPM: 116.6
2316 Male, age 76, right hemisphere 132.3
2407 Male, age 75, both hemispheres 130.3
2007 Male, age 72, unknown 124.0
1815 Male, age 53, unknown 121.0
1817 Female, age 42, unknown 116.9
2667 Female, age 75, unknown 112.4
2825 Male, age 18, unknown 112.3
1944 Female, age 72, unknown 109.0
1816 Male, age 51, unknown 108.3
2224 Female, age 72, unknown 108.0
2273 Male, age 74, both hemispheres 107.9
Red nucleus
nTPM: 134.6
2584 Male, age 75, left hemisphere 162.4
2588 Male, age 74, left hemisphere 147.5
2785 Male, age 18, unknown 145.7
2769 Male, age 72, unknown 141.2
1865 Male, age 51, unknown 138.9
2503 Female, age 72, unknown 136.3
2227 Male, age 72, unknown 135.5
1904 Male, age 53, unknown 132.5
2725 Female, age 75, unknown 127.7
2823 Male, age 76, right hemisphere 118.9
1954 Female, age 42, unknown 115.5
1821 Female, age 72, unknown 113.0
Substantia nigra
nTPM: 117.1
2665 Male, age 74, both hemispheres 130.9
2583 Male, age 75, right hemisphere 130.5
2699 Male, age 18, unknown 127.6
2590 Female, age 75, unknown 124.5
2409 Female, age 72, unknown 121.2
1851 Male, age 51, unknown 118.3
1941 Male, age 53, unknown 115.1
1889 Female, age 72, unknown 109.3
1916 Female, age 42, unknown 101.6
2241 Male, age 72, unknown 91.6
Superior colliculus
nTPM: 124.5
2664 Male, age 75, both hemispheres 148.1
1913 Female, age 42, unknown 142.4
1995 Male, age 72, unknown 139.4
2587 Male, age 74, left hemisphere 122.9
2668 Female, age 75, unknown 122.1
1839 Male, age 51, unknown 117.8
1796 Male, age 53, unknown 116.3
2087 Female, age 72, unknown 115.1
2261 Male, age 18, unknown 110.9
1895 Male, age 76, right hemisphere 110.2
Ventral tegmental area
nTPM: 116.2
2021 Male, age 53, unknown 128.9
2223 Female, age 72, unknown 119.3
1942 Male, age 51, unknown 118.5
2410 Female, age 72, unknown 113.7
2218 Male, age 76, both hemispheres 109.4
1915 Female, age 42, unknown 107.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

307.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 307.0
Samples: 139

Max nTPM: 979.7
Min nTPM: 112.8
Std nTPM: 114.4
Median nTPM: 291.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 979.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 661.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 609.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 533.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 502.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 493.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 483.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 481.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 475.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 472.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 470.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 467.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 459.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 456.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 455.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 445.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 444.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 444.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 440.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 438.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 424.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 406.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 400.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 396.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 384.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 381.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 378.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 374.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 374.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 372.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 371.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 367.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 366.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 362.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 356.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 355.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 354.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 351.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 345.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 345.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 338.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 338.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 334.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 334.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 329.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 328.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 327.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 326.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 323.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 323.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 322.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 321.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 319.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 317.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 316.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 315.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 314.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 313.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 312.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 309.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 306.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 306.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 305.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 303.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 302.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 302.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 300.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 298.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 293.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 291.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 289.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 286.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 286.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 284.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 284.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 282.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 278.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 277.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 275.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 274.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 274.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 273.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 270.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 268.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 268.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 268.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 264.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 262.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 260.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 256.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 255.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 254.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 253.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 252.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 245.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 245.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 240.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 239.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 239.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 233.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 232.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 226.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 225.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 222.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 220.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 219.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 218.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 216.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 216.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 214.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 214.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 212.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 210.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 210.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 205.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 204.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 203.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 201.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 198.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 198.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 197.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 196.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 195.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 192.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 192.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 191.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 189.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 185.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 185.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 182.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 182.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 181.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 180.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 171.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 159.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 140.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 123.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 123.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 112.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

74.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 74.7
FF:10158-103A5 76 years, female 74.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

64.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 64.6
Samples: 4

Max nTPM: 73.8
Min nTPM: 54.7
Sample A Female 73.8
Sample B Female 68.3
Sample C Male 54.7
Sample D Male 61.5
Midbrain
nTPM: 63.7
Samples: 4

Max nTPM: 110.1
Min nTPM: 37.2
Sample A Female 110.1
Sample B Female 61.6
Sample C Male 45.7
Sample D Male 37.2
Periaqueductal gray
nTPM: 53.8
Samples: 3

Max nTPM: 60.2
Min nTPM: 47.4
Sample B Female 53.9
Sample C Male 60.2
Sample D Male 47.4
Superior colliculi
nTPM: 62.3
Samples: 4

Max nTPM: 74.5
Min nTPM: 52.7
Sample A Female 68.5
Sample B Female 74.5
Sample C Male 52.7
Sample D Male 53.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

115.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 115.8
Samples: 4

Max nTPM: 122.4
Min nTPM: 110.6
Sample A Male 122.4
Sample B Male 110.6
Sample C Female 113.4
Sample D Female 116.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.0
73497547 Antisense, RP_051121_01_C07, Mouse strain C57BL/6J (56 days, male) 0.0

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