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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
127.5
nTPM
HPA:
63.1
nTPM
GTEx:
127.5
nTPM
FANTOM5:
271.3
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA068767
Cholangiocytes
Low
Hepatocytes
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
63.1
Female, age 60
Liver sample 21 nTPM: 74.1
Male, age 54
Liver sample 23 nTPM: 60.8
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 72
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 29.7
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 39.8
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 61.5
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 58.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 77.8
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 57.8
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 99.2
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
127.5
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 127.5
Samples: 226
Max nTPM: 213.4
Min nTPM: 70.3
Std nTPM: 24.8
Median nTPM: 124.6
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
213.4
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
211.2
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
198.8
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
197.1
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
186.4
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
185.6
GTEX-REY6-1226-SM-48FDR
60-69 years, male
178.5
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
175.4
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
175.2
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
174.6
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
171.5
GTEX-12696-0826-SM-5EGGE
60-69 years, male
169.9
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
168.1
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
168.1
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
166.9
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
165.0
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
164.6
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
163.1
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
162.5
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
162.4
GTEX-QESD-2026-SM-447BI
20-29 years, male
161.1
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
158.6
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
158.1
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
156.6
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
156.5
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
156.2
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
156.0
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
155.9
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
155.7
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
154.9
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
154.6
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
153.1
GTEX-14JG1-1626-SM-664NH
40-49 years, male
152.9
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
152.7
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
151.0
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
150.4
GTEX-R53T-0326-SM-48FEC
50-59 years, female
150.2
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
150.0
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
149.6
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
149.4
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
149.3
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
149.0
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
148.3
GTEX-YECK-1926-SM-4W21H
60-69 years, male
147.5
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
147.4
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
146.7
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
145.5
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
145.5
GTEX-1B932-1426-SM-793AN
40-49 years, female
145.2
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
145.1
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
144.9
GTEX-S32W-1926-SM-4AD63
50-59 years, female
144.0
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
143.9
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
143.6
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
143.6
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
142.0
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
141.8
GTEX-18A66-2026-SM-7189C
60-69 years, male
141.7
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
141.6
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
141.6
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
141.5
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
141.1
GTEX-S33H-1626-SM-4AD68
30-39 years, male
140.7
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
140.4
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
139.5
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
139.4
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
139.4
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
139.3
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
139.2
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
139.2
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
138.8
GTEX-P78B-1326-SM-3P611
40-49 years, female
138.6
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
138.4
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
138.0
GTEX-11ZUS-2526-SM-59872
30-39 years, male
137.8
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
137.2
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
136.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
136.7
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
136.5
GTEX-14XAO-0226-SM-68728
60-69 years, female
136.4
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
136.1
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
135.5
GTEX-QEL4-1226-SM-447A4
50-59 years, male
135.2
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
135.0
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
134.4
GTEX-18465-1626-SM-7LG6N
50-59 years, male
134.3
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
133.9
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
133.8
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
133.1
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
133.0
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
132.5
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
132.5
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
132.5
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
132.1
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
131.8
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
131.3
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
129.4
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
128.8
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
128.3
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
128.1
GTEX-RU72-1426-SM-46MUF
50-59 years, female
127.6
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
126.7
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
126.2
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
125.9
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
125.8
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
125.7
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
125.4
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
125.3
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
125.2
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
124.8
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
124.8
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
124.7
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
124.7
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
124.6
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
124.5
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
124.5
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
124.5
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
124.0
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
123.6
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
123.4
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
123.1
GTEX-18A7A-1526-SM-72D69
50-59 years, female
122.7
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
122.7
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
122.5
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
122.3
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
122.2
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
122.2
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
121.5
GTEX-X261-1726-SM-4PQYT
50-59 years, male
121.4
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
120.8
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
120.3
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
120.0
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
119.9
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
119.5
GTEX-17HHE-0126-SM-79398
50-59 years, male
119.3
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
119.1
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
118.9
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
118.9
GTEX-14PHX-0526-SM-664NW
50-59 years, male
118.8
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
118.6
GTEX-144GL-1426-SM-79OMA
50-59 years, male
118.5
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
118.1
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
118.1
GTEX-13112-1426-SM-5EGH8
50-59 years, male
118.0
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
117.8
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
117.6
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
117.3
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
117.3
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
116.8
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
116.6
GTEX-14E7W-1526-SM-6871X
70-79 years, male
116.6
GTEX-13113-1326-SM-5GCOI
60-69 years, female
116.2
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
114.4
GTEX-Q734-0326-SM-48U15
40-49 years, female
114.3
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
114.0
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
113.9
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
113.3
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
112.5
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
112.4
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
112.3
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
112.3
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
112.2
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
111.8
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
111.6
GTEX-O5YV-0726-SM-EV798
60-69 years, female
111.5
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
111.2
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
111.2
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
110.9
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
110.8
GTEX-RN64-1826-SM-48FDV
50-59 years, male
110.6
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
108.9
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
108.8
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
108.6
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
108.4
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
108.1
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
108.0
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
107.6
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
107.4
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
107.3
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
106.5
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
106.0
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
105.8
GTEX-11GSP-0626-SM-5986T
60-69 years, female
105.6
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
105.2
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
105.1
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
105.0
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
104.2
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
104.0
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
104.0
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
103.7
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
103.7
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
103.6
GTEX-17F96-1226-SM-79OK2
70-79 years, male
103.4
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
103.4
GTEX-1399T-0826-SM-5IFES
60-69 years, male
103.3
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
103.3
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
102.6
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
101.6
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
101.4
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
101.2
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
101.0
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
100.5
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
100.3
GTEX-14PJO-1726-SM-68719
60-69 years, male
99.5
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
99.4
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
98.7
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
97.9
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
97.6
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
96.8
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
96.4
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
95.7
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
94.7
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
93.9
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
92.8
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
91.3
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
86.7
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
85.9
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
85.7
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
83.7
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
82.8
GTEX-1B933-1226-SM-731DW
50-59 years, female
82.2
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
77.1
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
77.0
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
75.5
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
75.1
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
70.3
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
