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TMEM176B
HPA
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  • TMEM176B
TISSUE PRIMARY DATA SMALL INTESTINE Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN ORAL MUCOSA
OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Small intestine
Tissue proteome
Intestine
SMALL INTESTINE - Expression summary
Protein expression
Small intestinei

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

h
m
l
n
Glandular cells: High
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:278.7 nTPM
HPA:269.9 nTPM
GTEx:278.7 nTPM
FANTOM5:409.0 Scaled Tags Per Million

SMALL INTESTINE - Antibody stainingi

Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.

Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.

Antibody HPA047509
Glandular cells High



SMALL INTESTINE - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

269.9
overview
Male, age 65
Small intestine sample 232
nTPM: 173.3
Cell types%
Glandular cells:
55

Smooth muscle cells:
5

Other cell types:
40

overview
Male, age 39
Small intestine sample 233
nTPM: 361.3
Cell types%
Glandular cells:
40

Smooth muscle cells:
5

Other cell types:
55

overview
Male, age 68
Small intestine sample 234
nTPM: 276.6
Cell types%
Glandular cells:
30

Smooth muscle cells:
15

Other cell types:
55

N/A
Male, age 85
Small intestine sample 235
nTPM: 268.3

SMALL INTESTINE - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

278.7
GTEx sample id Sample description nTPM
Small Intestine - Terminal Ileum
Average nTPM: 278.7
Samples: 187

Max nTPM: 600.3
Min nTPM: 12.4
Std nTPM: 120.2
Median nTPM: 262.3
GTEX-X5EB-1626-SM-4E3IV 40-49 years, male 600.3
GTEX-13FTW-2026-SM-5IJE2 40-49 years, male 579.1
GTEX-ZTX8-0526-SM-59HLD 20-29 years, male 568.7
GTEX-1R9K5-2026-SM-E6CPS 50-59 years, male 566.5
GTEX-ZA64-1226-SM-5HL7B 20-29 years, male 564.6
GTEX-YEC4-1726-SM-4W21E 40-49 years, male 559.6
GTEX-1NSGN-2126-SM-DPRYN 50-59 years, male 545.4
GTEX-YFCO-1326-SM-664NV 40-49 years, male 527.8
GTEX-14DAR-1426-SM-5RQIR 50-59 years, male 524.3
GTEX-15G1A-1726-SM-6LPI4 30-39 years, male 522.6
GTEX-ZYFG-2026-SM-5E43Y 60-69 years, female 520.2
GTEX-1B8KE-1726-SM-7IGMN 50-59 years, male 509.1
GTEX-14PJ6-1726-SM-6AJBN 60-69 years, female 492.1
GTEX-13PL7-2626-SM-5IFH4 60-69 years, female 489.3
GTEX-111YS-1426-SM-5GID8 60-69 years, male 489.2
GTEX-Y9LG-1626-SM-5IFHM 30-39 years, male 482.9
GTEX-ZDTT-1726-SM-5HL69 60-69 years, male 457.1
GTEX-XBED-1426-SM-4AT4G 60-69 years, male 451.2
GTEX-13CF3-1226-SM-5LZXN 60-69 years, female 446.5
GTEX-Y5LM-1626-SM-4VDTB 40-49 years, female 438.7
GTEX-1GMR2-1026-SM-7MKHJ 50-59 years, male 435.8
GTEX-XXEK-1026-SM-4BRUW 50-59 years, male 433.2
GTEX-ZVZP-1826-SM-5GZXB 50-59 years, male 430.2
GTEX-1JMQK-2426-SM-CXZJU 60-69 years, male 428.2
GTEX-144GM-1026-SM-79OKU 20-29 years, male 417.2
GTEX-14PN3-2026-SM-68729 60-69 years, female 407.9
GTEX-YB5E-1526-SM-5IFIE 40-49 years, male 403.4
GTEX-14PJN-0826-SM-686ZL 30-39 years, male 398.9
GTEX-16MTA-1526-SM-6LPJB 50-59 years, male 394.6
GTEX-14XAO-1926-SM-6ETZO 60-69 years, female 391.3
GTEX-VJYA-0926-SM-4KL1N 60-69 years, male 390.9
GTEX-ZTSS-0926-SM-59865 40-49 years, male 389.3
GTEX-XUZC-1426-SM-4BRV3 30-39 years, female 387.7
GTEX-139YR-2226-SM-5IFFW 50-59 years, male 382.4
GTEX-YF7O-1826-SM-5IFIU 50-59 years, male 382.0
GTEX-1R9K4-2326-SM-E6CRB 60-69 years, male 377.0
GTEX-1122O-1326-SM-5H11F 60-69 years, female 375.5
GTEX-1MUQO-2426-SM-EAZ5A 60-69 years, male 374.5
GTEX-1J8Q3-2526-SM-CNNQ4 60-69 years, male 370.4
GTEX-ZTPG-2626-SM-57WFX 20-29 years, female 366.3
GTEX-145LT-1026-SM-5LU9O 40-49 years, male 364.4
GTEX-13113-1226-SM-5EGHT 60-69 years, female 363.2
GTEX-1AMFI-1926-SM-731F2 50-59 years, female 360.7
GTEX-11P7K-1626-SM-5GU63 30-39 years, male 358.2
GTEX-ZLV1-1126-SM-4WWBW 60-69 years, female 355.8
GTEX-ZXES-1526-SM-5NQ95 30-39 years, female 353.8
GTEX-ZVT2-2126-SM-5NQ93 50-59 years, female 353.2
GTEX-1R7EU-1326-SM-E6CQ6 60-69 years, male 351.8
GTEX-13D11-0726-SM-5LZZB 50-59 years, female 349.3
GTEX-1QP2A-2426-SM-EXOJA 50-59 years, male 347.2
GTEX-WQUQ-2426-SM-4MVNW 60-69 years, male 346.0
GTEX-11I78-1126-SM-5A5K5 50-59 years, female 343.6
GTEX-131XF-1326-SM-5GCMQ 60-69 years, male 341.1
GTEX-ZPCL-1726-SM-57WEO 60-69 years, female 340.1
GTEX-13RTK-0826-SM-5Q5C6 20-29 years, male 331.7
GTEX-ZLWG-1626-SM-DNZZ1 50-59 years, female 331.7
GTEX-14PKV-2026-SM-6AJ9A 20-29 years, female 330.3
GTEX-15EU6-1826-SM-7PC1W 50-59 years, male 329.7
GTEX-ZG7Y-1926-SM-DNZZ5 50-59 years, male 325.5
GTEX-16AAH-1426-SM-7KFTR 50-59 years, male 324.9
GTEX-1R7EV-1226-SM-DTX82 40-49 years, male 321.0
GTEX-1399R-2026-SM-5K7WN 30-39 years, male 319.9
GTEX-WY7C-1826-SM-4ONCE 50-59 years, male 319.6
GTEX-1K9T9-2726-SM-D4P3E 50-59 years, female 317.8
GTEX-WHSB-1026-SM-4M1XN 50-59 years, male 317.5
GTEX-1C64O-2526-SM-79ONO 60-69 years, male 316.0
GTEX-ZPIC-2326-SM-57WDW 40-49 years, female 314.4
GTEX-139T6-1026-SM-5IJGC 50-59 years, male 314.0
GTEX-133LE-1426-SM-5IFH1 20-29 years, female 311.3
GTEX-XAJ8-0526-SM-47JYK 40-49 years, male 304.0
GTEX-13X6H-1826-SM-7EWCZ 50-59 years, female 301.8
GTEX-11DXZ-1326-SM-5H11X 50-59 years, male 301.3
GTEX-18A66-2526-SM-7KFTZ 60-69 years, male 294.7
GTEX-14E6E-1626-SM-5RQI7 30-39 years, male 294.4
GTEX-1JK1U-1226-SM-CNNPN 60-69 years, male 293.2
GTEX-11EQ9-1326-SM-5985X 30-39 years, male 291.4
GTEX-ZZ64-0526-SM-5GZXM 20-29 years, male 290.4
GTEX-ZVP2-1726-SM-5GU5P 50-59 years, male 284.6
GTEX-1CAMR-0826-SM-7MKFK 20-29 years, male 283.1
GTEX-11NSD-1726-SM-5N9C3 20-29 years, male 279.0
GTEX-1CAMS-2426-SM-7DHMV 40-49 years, female 277.9
GTEX-14PK6-1626-SM-6871I 70-79 years, female 276.7
GTEX-1L5NE-1826-SM-EV79T 50-59 years, male 276.4
GTEX-VUSG-1726-SM-4KKZL 50-59 years, male 270.7
GTEX-ZEX8-1826-SM-57WBH 50-59 years, male 268.7
GTEX-X15G-1426-SM-4PQZK 50-59 years, female 267.9
GTEX-11DXX-1626-SM-5H11H 60-69 years, female 267.4
GTEX-WFJO-0926-SM-4LVM2 30-39 years, male 265.8
GTEX-13O21-1026-SM-5IJDU 50-59 years, male 265.1
GTEX-1J8QM-1026-SM-C1YQA 60-69 years, female 264.1
GTEX-XGQ4-1326-SM-4GIDU 50-59 years, male 263.4
GTEX-1LH75-1926-SM-DIPGD 50-59 years, female 263.4
GTEX-1BAJH-2526-SM-7IGOT 70-79 years, male 262.3
GTEX-1R9PM-1626-SM-DPRY9 20-29 years, male 262.3
GTEX-UPK5-2026-SM-4JBIM 40-49 years, male 261.7
GTEX-1QPFJ-2626-SM-DPRZU 30-39 years, female 256.6
GTEX-1MGNQ-2326-SM-EV7BG 40-49 years, male 256.5
GTEX-Y3IK-1726-SM-4YCCR 50-59 years, female 255.8
GTEX-1399S-2026-SM-5KM4B 30-39 years, female 255.1
GTEX-ZC5H-2326-SM-4WAYT 40-49 years, female 255.0
GTEX-1IKOE-1926-SM-ARU7V 30-39 years, female 251.5
GTEX-1GMR3-2726-SM-7MKFB 40-49 years, male 251.4
GTEX-148VJ-2226-SM-5NQ9M 70-79 years, male 250.3
GTEX-11P82-0826-SM-5P9GU 20-29 years, male 249.1
GTEX-ZP4G-1626-SM-57WGD 20-29 years, female 247.9
GTEX-1HSMQ-2226-SM-C1YRD 50-59 years, male 247.6
GTEX-1OJC3-1626-SM-E9U65 20-29 years, male 246.5
GTEX-1CB4F-1826-SM-7MGXI 60-69 years, male 246.2
GTEX-1497J-1926-SM-5TDCC 60-69 years, male 244.3
GTEX-145ME-0926-SM-5O9AR 40-49 years, female 242.9
GTEX-Z9EW-0926-SM-5CVMM 40-49 years, male 241.8
GTEX-16A39-1426-SM-6LLI6 30-39 years, female 241.6
GTEX-1RAZA-1826-SM-DTXA2 20-29 years, male 237.8
GTEX-1PDJ9-1826-SM-E9U66 20-29 years, male 236.9
GTEX-Y114-1426-SM-4TT6W 50-59 years, female 236.6
GTEX-1KXAM-2026-SM-DHXKI 60-69 years, male 236.2
GTEX-1B8KZ-1126-SM-7IGLX 50-59 years, male 234.0
GTEX-14PJ3-1326-SM-664O7 50-59 years, male 233.2
GTEX-1H1DE-1426-SM-9JGHV 20-29 years, male 228.3
GTEX-WRHK-1026-SM-4MVOD 20-29 years, female 227.3
GTEX-WFG8-1626-SM-4LVMB 20-29 years, male 227.1
GTEX-14BMU-1426-SM-5TDE5 20-29 years, female 225.5
GTEX-13111-1426-SM-5DUW3 50-59 years, male 225.4
GTEX-17MFQ-1026-SM-7KFSZ 20-29 years, male 223.9
GTEX-WH7G-1626-SM-4LVMY 40-49 years, male 222.7
GTEX-12BJ1-1926-SM-5HL9Z 60-69 years, male 218.1
GTEX-13NYB-1826-SM-5J1N3 40-49 years, male 218.0
GTEX-1C475-1426-SM-793CH 40-49 years, female 215.5
GTEX-1JN76-1126-SM-C1YRL 20-29 years, female 211.5
GTEX-131XG-1726-SM-5LZUR 50-59 years, female 205.3
GTEX-1192X-2526-SM-59868 50-59 years, male 205.1
GTEX-13QBU-1926-SM-5IJEW 40-49 years, female 203.3
GTEX-1PIEJ-1526-SM-E6CP8 20-29 years, female 203.3
GTEX-1F75I-2526-SM-9WPOZ 40-49 years, male 202.8
GTEX-11XUK-1426-SM-5EQMG 40-49 years, female 202.0
GTEX-1EMGI-2826-SM-7IGMR 60-69 years, male 200.5
GTEX-13FH7-1226-SM-5IJFK 50-59 years, female 199.9
GTEX-1QW4Y-1226-SM-EWRMY 30-39 years, male 199.4
GTEX-14PKU-1626-SM-6871C 40-49 years, female 197.2
GTEX-ZF29-1626-SM-4WKFJ 60-69 years, female 195.1
GTEX-WFG7-1726-SM-4LVME 20-29 years, male 192.1
GTEX-1399U-2126-SM-5IFEZ 50-59 years, female 191.5
GTEX-ZLFU-1526-SM-4WWBT 40-49 years, male 190.6
GTEX-1RAZQ-2226-SM-DPRZR 30-39 years, male 190.5
GTEX-ZQG8-2526-SM-57WEQ 60-69 years, female 188.8
GTEX-1AX8Z-2526-SM-731E3 60-69 years, male 187.2
GTEX-13O61-1326-SM-5KM31 60-69 years, male 187.1
GTEX-1JJE9-2226-SM-CXZJM 70-79 years, male 186.9
GTEX-11TUW-1926-SM-5BC58 60-69 years, male 183.7
GTEX-1RAZR-1826-SM-E6CRE 40-49 years, male 182.3
GTEX-Y111-2226-SM-4SOJB 50-59 years, male 181.9
GTEX-15DZA-0826-SM-6AJBF 30-39 years, female 181.7
GTEX-1LBAC-1526-SM-CXZKU 20-29 years, male 179.6
GTEX-Y5V5-1826-SM-4VDS5 60-69 years, female 177.6
GTEX-1H11D-2526-SM-9JGGU 40-49 years, male 175.9
GTEX-1GL5R-2026-SM-7MKHP 50-59 years, male 174.8
GTEX-183FY-1626-SM-793D8 20-29 years, male 174.6
GTEX-1S5ZA-1326-SM-EV7BB 20-29 years, male 172.8
GTEX-17HHE-1726-SM-79OKT 50-59 years, male 171.3
GTEX-18QFQ-1626-SM-72D7H 30-39 years, male 161.4
GTEX-14C39-1826-SM-5ZZW4 40-49 years, male 157.3
GTEX-16NGA-1126-SM-7KFSY 40-49 years, female 151.8
GTEX-1QP28-1726-SM-E6CRK 50-59 years, female 149.0
GTEX-11VI4-1626-SM-5EQKO 40-49 years, female 144.6
GTEX-111CU-1326-SM-5NQ8L 50-59 years, male 144.2
GTEX-WEY5-1526-SM-4LMJF 40-49 years, female 135.5
GTEX-XMK1-1826-SM-4B66F 40-49 years, male 130.0
GTEX-12WSK-1526-SM-5CVNO 40-49 years, female 129.2
GTEX-1S82Z-1826-SM-E9TIK 30-39 years, female 122.9
GTEX-WFON-1526-SM-4LVMP 40-49 years, male 117.8
GTEX-1OKEX-1126-SM-DTXEB 60-69 years, male 117.5
GTEX-1R9JW-1926-SM-EVR4J 30-39 years, female 109.9
GTEX-ZAB5-1526-SM-5HL9P 50-59 years, male 109.5
GTEX-17KNJ-1626-SM-718AL 50-59 years, male 108.9
GTEX-1LGOU-1426-SM-D3L8N 20-29 years, female 106.6
GTEX-117YX-0326-SM-5GICL 50-59 years, male 104.6
GTEX-1QCLZ-2126-SM-EWRNC 60-69 years, female 101.2
GTEX-13OVI-1926-SM-5IJCG 60-69 years, female 100.3
GTEX-WYJK-1526-SM-4ONCW 50-59 years, male 93.6
GTEX-ZF2S-1726-SM-57WFT 50-59 years, female 93.6
GTEX-XPVG-1726-SM-4B65W 50-59 years, male 89.6
GTEX-1I1GT-1826-SM-ARZLW 60-69 years, female 82.9
GTEX-ZQUD-0926-SM-57WE3 30-39 years, male 79.4
GTEX-131XE-0926-SM-5HL7J 50-59 years, male 76.1
GTEX-Y3I4-1326-SM-4TT8Z 50-59 years, male 73.2
GTEX-11LCK-1926-SM-5A5KE 30-39 years, male 70.3
GTEX-13W3W-2026-SM-5K7UL 60-69 years, female 12.4
Show allShow less

SMALL INTESTINE - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

409.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Small intestine
Scaled Tags Per Million: 409.0
FF:10024-101D6 15,40,85 years, mixed 409.0

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