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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:217.5 nTPM
HPA Brain:150.6 nTPM
GTEx:217.5 nTPM
FANTOM5:78.7 Scaled Tags Per Million
Pig:97.2 nTPM
Mouse:14.1 nTPM
Allen mouse:0.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

150.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 114.4
1870 Female, age 42, unknown 138.7
2666 Male, age 74, left hemisphere 131.6
1830 Male, age 51, unknown 130.2
2828 Female, age 72, unknown 124.7
1833 Male, age 53, unknown 123.7
2586 Male, age 75, left hemisphere 109.1
2411 Female, age 72, unknown 109.0
2019 Male, age 18, unknown 98.0
2219 Male, age 76, both hemispheres 91.6
1827 Male, age 72, unknown 87.9
Dorsal raphe nucleus
nTPM: 94.6
2750 Male, age 76, both hemispheres 132.3
1828 Male, age 53, unknown 100.3
2016 Female, age 72, unknown 97.8
2047 Male, age 72, unknown 75.8
2298 Female, age 72, unknown 66.7
Inferior colliculus
nTPM: 85.7
2849 Male, age 72, unknown 109.8
1890 Male, age 53, unknown 86.1
1848 Female, age 42, unknown 86.0
2097 Female, age 72, unknown 60.9
Median raphe nucleus
nTPM: 116.2
2220 Male, age 76, midline 116.2
Periaquaductal grey, anterior
nTPM: 73.3
1795 Male, age 51, unknown 79.4
1947 Male, age 18, unknown 71.4
2502 Female, age 75, unknown 69.2
Periaquaductal grey, dorsal
nTPM: 83.9
2464 Female, age 72, unknown 92.6
2850 Male, age 76, both hemispheres 88.1
1831 Male, age 72, unknown 80.2
1840 Male, age 53, unknown 74.7
Periaquaductal grey, lateral
nTPM: 76.7
2053 Male, age 18, unknown 87.0
2140 Male, age 76, both hemispheres 75.4
2272 Male, age 74, both hemispheres 67.6
Pretectal area
nTPM: 77.0
1815 Male, age 53, unknown 94.4
2825 Male, age 18, unknown 88.8
2316 Male, age 76, right hemisphere 87.5
2407 Male, age 75, both hemispheres 82.4
1817 Female, age 42, unknown 80.8
2224 Female, age 72, unknown 78.9
2667 Female, age 75, unknown 72.6
2007 Male, age 72, unknown 70.6
1944 Female, age 72, unknown 65.4
1816 Male, age 51, unknown 64.5
2273 Male, age 74, both hemispheres 61.0
Red nucleus
nTPM: 150.6
2769 Male, age 72, unknown 187.8
2227 Male, age 72, unknown 175.4
1865 Male, age 51, unknown 163.0
2588 Male, age 74, left hemisphere 162.9
2503 Female, age 72, unknown 161.8
2823 Male, age 76, right hemisphere 160.0
1904 Male, age 53, unknown 145.7
1821 Female, age 72, unknown 137.3
1954 Female, age 42, unknown 136.1
2785 Male, age 18, unknown 131.0
2725 Female, age 75, unknown 130.7
2584 Male, age 75, left hemisphere 115.8
Substantia nigra
nTPM: 97.3
2699 Male, age 18, unknown 132.4
2583 Male, age 75, right hemisphere 129.9
2665 Male, age 74, both hemispheres 110.3
1851 Male, age 51, unknown 101.7
2590 Female, age 75, unknown 98.2
1916 Female, age 42, unknown 95.4
1889 Female, age 72, unknown 83.1
1941 Male, age 53, unknown 81.7
2409 Female, age 72, unknown 76.2
2241 Male, age 72, unknown 64.3
Superior colliculus
nTPM: 96.6
1913 Female, age 42, unknown 135.5
1995 Male, age 72, unknown 126.0
2668 Female, age 75, unknown 115.6
2587 Male, age 74, left hemisphere 106.2
1839 Male, age 51, unknown 93.4
1796 Male, age 53, unknown 93.1
1895 Male, age 76, right hemisphere 81.3
2664 Male, age 75, both hemispheres 77.9
2261 Male, age 18, unknown 68.5
2087 Female, age 72, unknown 68.1
Ventral tegmental area
nTPM: 110.1
2223 Female, age 72, unknown 177.8
2218 Male, age 76, both hemispheres 105.5
2410 Female, age 72, unknown 104.7
2021 Male, age 53, unknown 95.0
1915 Female, age 42, unknown 90.9
1942 Male, age 51, unknown 87.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

217.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 217.5
Samples: 139

Max nTPM: 838.0
Min nTPM: 47.6
Std nTPM: 126.6
Median nTPM: 182.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 838.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 735.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 649.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 622.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 497.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 468.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 448.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 445.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 422.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 421.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 420.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 391.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 383.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 382.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 364.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 358.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 358.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 349.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 347.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 334.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 334.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 331.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 313.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 301.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 291.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 291.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 286.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 286.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 283.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 278.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 277.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 274.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 273.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 273.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 268.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 262.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 261.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 260.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 260.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 256.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 240.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 227.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 225.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 223.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 222.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 220.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 219.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 218.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 216.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 214.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 211.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 207.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 206.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 205.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 203.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 201.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 199.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 197.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 196.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 193.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 189.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 187.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 186.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 185.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 184.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 184.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 183.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 183.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 182.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 182.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 181.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 181.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 175.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 174.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 173.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 173.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 172.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 172.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 171.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 171.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 167.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 166.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 163.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 160.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 158.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 154.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 153.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 153.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 152.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 152.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 151.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 150.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 149.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 149.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 148.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 148.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 147.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 145.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 144.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 144.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 144.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 144.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 142.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 142.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 141.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 140.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 139.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 138.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 135.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 134.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 131.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 125.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 125.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 123.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 122.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 122.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 118.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 118.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 116.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 115.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 114.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 114.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 114.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 110.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 108.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 108.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 105.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 104.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 101.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 98.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 95.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 93.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 92.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 86.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 79.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 79.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 74.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 57.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 47.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

78.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 78.7
FF:10158-103A5 76 years, female 78.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

97.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 82.1
Samples: 4

Max nTPM: 99.3
Min nTPM: 61.7
Sample A Female 99.3
Sample B Female 61.7
Sample C Male 92.8
Sample D Male 74.6
Midbrain
nTPM: 97.2
Samples: 4

Max nTPM: 112.2
Min nTPM: 84.8
Sample A Female 112.2
Sample B Female 84.8
Sample C Male 91.8
Sample D Male 100.1
Periaqueductal gray
nTPM: 81.9
Samples: 3

Max nTPM: 92.0
Min nTPM: 73.6
Sample B Female 80.1
Sample C Male 92.0
Sample D Male 73.6
Superior colliculi
nTPM: 90.4
Samples: 4

Max nTPM: 115.4
Min nTPM: 58.7
Sample A Female 115.4
Sample B Female 58.7
Sample C Male 92.6
Sample D Male 94.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

14.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 14.1
Samples: 4

Max nTPM: 15.6
Min nTPM: 12.2
Sample A Male 15.1
Sample B Male 13.5
Sample C Female 12.2
Sample D Female 15.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.3
69202358 Antisense, RP_050324_03_E03, Mouse strain C57BL/6J (56 days, male) 0.4
72340126 Antisense, RP_051101_02_A06, Mouse strain C57BL/6J (56 days, male) 0.1

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